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Shinya Yamanaka

Shinya Yamanaka

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
131
Citations
137736
World Ranking
179
National Ranking
15

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2012 - Nobel Prize for the discovery that mature cells can be reprogrammed to become pluripotent
  • 2011 - Member of the National Academy of Sciences
  • 2008 - Robert Koch Prize

Overview

Shinya Yamanaka is affiliated with Kyoto University in Japan and has significantly contributed to the fields of biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology and physiology, with subfields including infectious diseases, insect science, and genetics.

The scientist's main topics of study cover several areas:

  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • Biomedical Ethics and Regulation
  • SARS-CoV-2 and COVID-19 Research
  • Renal and related cancers
  • RNA Research and Splicing
  • Insect Utilization and Effects

Yamanaka's frequent co-authors include:

  • Kazutoshi Takahashi
  • Megumi Narita
  • Mio Iwasaki
  • Michiko Nakamura
  • Chikako Okubo

Their work has been published in various venues, with recurrent appearances in:

  • Stem Cell Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports Methods
  • Journal Of Biochemical Technology
  • Cell stem cell

Recent papers authored or co-authored by Yamanaka include:

  • "Pluripotent Stem Cell-Based Cell Therapy-Promise and Challenges" (2020) published in Cell stem cell
  • "First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol" (2021), published in Regenerative Therapy
  • "A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population" (2022), published in Med
  • "Dual inhibition of TMPRSS2 and Cathepsin B prevents SARS-CoV-2 infection in iPS cells" (2021), published in Molecular Therapy - Nucleic Acids
  • "Improved Sendai viral system for reprogramming to naive pluripotency" (2022), published in Cell Reports Methods

Yamanaka's research integrates advancements in stem cell technologies and regenerative medicine, with clinical applications such as stem cell transplantation and infectious disease prevention. The scientist's work encompasses both experimental methodologies and ethical considerations related to biomedical research.

Awards received by Yamanaka include:

  • The Nobel Prize in 2012 for the discovery that mature cells can be reprogrammed to become pluripotent
  • Membership in the National Academy of Sciences in 2011
  • The Robert Koch Prize in 2008

Best Publications

  • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

    Kazutoshi Takahashi;Shinya Yamanaka

  • Induction of Pluripotent Stem Cells From Adult Human Fibroblasts by Defined Factors

    Kazutoshi Takahashi;Koji Tanabe;Mari Ohnuki;Megumi Narita

  • Generation of germline-competent induced pluripotent stem cells

    Keisuke Okita;Tomoko Ichisaka;Shinya Yamanaka

  • The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells

    Kaoru Mitsui;Yoshimi Tokuzawa;Hiroaki Itoh;Kohichi Segawa

  • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

    Masato Nakagawa;Michiyo Koyanagi;Koji Tanabe;Kazutoshi Takahashi

  • Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.

    Atsunori Fukuhara;Morihiro Matsuda;Masako Nishizawa;Katsumori Segawa

  • Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

    Keisuke Okita;Masato Nakagawa;Hong Hyenjong;Tomoko Ichisaka

  • A more efficient method to generate integration-free human iPS cells

    Keisuke Okita;Yasuko Matsumura;Yoshiko Sato;Aki Okada

  • Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

    Hyenjong Hong;Kazutoshi Takahashi;Tomoko Ichisaka;Takashi Aoi

  • Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells

    Takashi Aoi;Kojiro Yae;Masato Nakagawa;Tomoko Ichisaka

  • Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration

    Michiko Mandai;Akira Watanabe;Yasuo Kurimoto;Yasuhiko Hirami

  • Induced pluripotent stem cell technology: a decade of progress

    Yanhong Shi;Haruhisa Inoue;Joseph C. Wu;Shinya Yamanaka

  • Induction of pluripotent stem cells from fibroblast cultures.

    Kazutoshi Takahashi;Keisuke Okita;Masato Nakagawa;Shinya Yamanaka

  • Nanog is the gateway to the pluripotent ground state.

    Jose Silva;Jose Silva;Jennifer Nichols;Jennifer Nichols;Thorold W. Theunissen;Thorold W. Theunissen;Ge Guo;Ge Guo

  • Variation in the safety of induced pluripotent stem cell lines

    Kyoko Miura;Yohei Okada;Takashi Aoi;Aki Okada

  • Strategies and New Developments in the Generation of Patient-Specific Pluripotent Stem Cells

    Shinya Yamanaka

  • Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells

    Yoshinori Yoshida;Kazutoshi Takahashi;Keisuke Okita;Tomoko Ichisaka

  • Induced Pluripotent Stem Cells: Past, Present, and Future

    Shinya Yamanaka

  • Nuclear reprogramming to a pluripotent state by three approaches

    Shinya Yamanaka;Helen M. Blau

  • Visfatin : A protein secreted by visceral fat that mimics the effects of insulin

    Atsunori Fukuhara;Morihiro Matsuda;Masako Nishizawa;Katsumori Segawa

Frequent Co-Authors

Kazutoshi Takahashi
Kazutoshi Takahashi New York Stem Cell Foundation
Keisuke Okita
Keisuke Okita Kyoto University
Masato Nakagawa
Masato Nakagawa Kyoto University
Katsuyuki Miura
Katsuyuki Miura Shiga University of Medical Science
Akira Watanabe
Akira Watanabe Kyoto University
Hideyuki Okano
Hideyuki Okano Keio University
Tatsutoshi Nakahata
Tatsutoshi Nakahata Kyoto University
Takuya Yamamoto
Takuya Yamamoto Kyoto University
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
Toshio Heike
Toshio Heike Kyoto University

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