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D-Index & Metrics

Molecular Biology

D-Index
60
Citations
11690
World Ranking
1974
National Ranking
982

Overview

Lei Li is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with additional contributions to agricultural and biological sciences.

Lei Li's work spans multiple subfields, including molecular biology, plant science, ecology, evolution, behavior and systematics, cellular and molecular neuroscience, and cancer research.

The main topics in their research include:

  • DNA repair mechanisms
  • CRISPR and genetic engineering
  • Fungal plant pathogen control
  • Neurobiology and insect physiology research
  • Plant molecular biology research
  • RNA modifications and cancer
  • Epigenetics and DNA methylation

The scientist has published recent papers in recognized scientific journals. These include:

  • Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure, 2020, Nature Genetics
  • AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity, 2022, Molecular Cell
  • A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia, 2020, Molecular Cell
  • The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks, 2020, Cell Reports
  • C17orf53 is identified as a novel gene involved in inter-strand crosslink repair, 2020, DNA repair

Lei Li frequently collaborates with other researchers in their field. Their regular co-authors include Yanyan Tian, Erica J. Lynn, Xi Shen, Rui Wang, and Junjie Chen.

Their publications commonly appear in venues such as Molecular Cell, bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature Genetics, and Cell Reports.

Best Publications

  • Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

    Theo A Knijnenburg;Linghua Wang;Michael T Zimmermann;Nyasha Chambwe

  • The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

    Karla A. Henning;Lei Li;Narayan Iyer;Lisa D. McDaniel

  • Specific association between the human DNA repair proteins XPA and ERCC1

    Lei Li;Stephen J. Elledge;Carolyn A. Peterson;Elise S. Bales

  • Combination of EGFR, HER-2/neu, and HER-3 Is a Stronger Predictor for the Outcome of Oral Squamous Cell Carcinoma Than Any Individual Family Members

    Weiya Xia;Yiu Keung Lau;Hua Zhong Zhang;Fen Yuan Xiao

  • Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck.

    Erich M. Sturgis;Edward J. Castillo;Lei Li;Rong Zheng

  • An interaction between the DNA repair factor XPA and replication protein A appears essential for nucleotide excision repair.

    Lei Li;Xiaoyan Lu;Carolyn A. Peterson;Randy J. Legerski

  • BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

    Leonard Wu;Csanad Z. Bachrati;Jiongwen Ou;Chang Xu

  • XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis.

    Erich M. Sturgis;Rong Zheng;Lei Li;Edward J. Castillo

  • A histone-fold complex and FANCM form a conserved DNA remodeling complex to maintain genome stability

    Zhijiang Yan;Mathieu Delannoy;Chen Ling;Danielle Daee

  • Inhibition of Nucleotide Excision Repair by the Cyclin-dependent Kinase Inhibitor p21

    Zhen-Qiang Pan;Joyce T. Reardon;Lei Li;Hernan Flores-Rozas

  • Strong correlation between c-erbB-2 overexpression and overall survival of patients with oral squamous cell carcinoma.

    Weiya Xia;Yiu Keung Lau;Hua Zhong Zhang;Ai Ru Liu

  • BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

    Jinhu Yin;Alexandra Sobeck;Chang Xu;Amom Ruhikanta Meetei

  • Involvement of Nucleotide Excision Repair in a Recombination-Independent and Error-Prone Pathway of DNA Interstrand Cross-Link Repair

    Xin Wang;Carolyn A. Peterson;Huyong Zheng;Rodney S. Nairn

  • Nucleotide Excision Repair- and Polymerase η-Mediated Error-Prone Removal of Mitomycin C Interstrand Cross-Links

    Huyong Zheng;Xin Wang;Amy J. Warren;Randy J. Legerski

  • High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma

    Weiya Xia;Yiu Keung Lau;Mickey C.T. Hu;Lei Li

  • Mutations in XPA That Prevent Association with ERCC1 Are Defective in Nucleotide Excision Repair

    Lei Li;Carolyn A. Peterson;Xiaoyan Lu;Randy J. Legerski

  • Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1

    J.-S. Rhee;L. Y. Li;L. Y. Li;O.-H. Shin;J.-C. Rah

  • Characterization of molecular defects in xeroderma pigmentosum group C.

    Lei Li;Elise S. Bales;Carolyn A. Peterson;Randy J. Legerski

  • The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links

    Nianxiang Zhang;Ramandeep Kaur;Xiaoyan Lu;Xi Shen

  • Cellular responses to ionizing radiation damage

    Lei Li;Michael Story;D. Randy J. Legerski

Frequent Co-Authors

Junjie Chen
Junjie Chen The University of Texas MD Anderson Cancer Center
Qingyi Wei
Qingyi Wei Duke University
Weidong Wang
Weidong Wang National Institutes of Health
Asif Rashid
Asif Rashid The University of Texas MD Anderson Cancer Center
Pierre D. McCrea
Pierre D. McCrea The University of Texas MD Anderson Cancer Center
Michael M. Seidman
Michael M. Seidman National Institutes of Health
Lee Zou
Lee Zou Duke University
Xiaoping Su
Xiaoping Su The University of Texas MD Anderson Cancer Center
Patrizia Farci
Patrizia Farci National Institutes of Health
Stephen J. Elledge
Stephen J. Elledge Harvard University

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