World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
59
Citations
10694
World Ranking
2032
National Ranking
1008

Overview

Michael M. Seidman is affiliated with the National Institutes of Health in the United States. Their research primarily falls within the domain of Biochemistry, Genetics, and Molecular Biology, with a specific emphasis on Molecular Biology as shown by their extensive publication record in this subfield. Their work also spans Cell Biology, Plant Science, Oncology, and Cancer Research.

The scientist's research interests focus on several main topics including DNA Repair Mechanisms, Genomics and Chromatin Dynamics, and DNA and Nucleic Acid Chemistry. Additional topics covered in their publications include Epigenetics and DNA Methylation, Microtubule and mitosis dynamics, CRISPR and Genetic Engineering, and Chromosomal and Genetic Variations.

Michael M. Seidman's frequent coauthors include Marina A. Bellani, Durga Pokharel, Althaf Shaik, Himabindu Gali, and Ryan C. James. The collaboration patterns reflect ongoing partnerships within their research network. The venues where their work is commonly published include bioRxiv (Cold Spring Harbor Laboratory), DNA repair, Nature Communications, Frontiers in Genetics, and Cell Reports.

Recent publications by Michael M. Seidman illustrate a focus on DNA repair and replication processes. Some of these include:

  • Repair of genomic interstrand crosslinks, 2024, DNA repair
  • RNF4 Regulates the BLM Helicase in Recovery From Replication Fork Collapse, 2021, Frontiers in Genetics
  • RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair, 2021, Cell Reports
  • DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain, 2020, Nature Communications
  • FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links, 2020, Nucleic Acids Research

The repetition of themes related to DNA damage repair and cellular replication mechanisms reflects the core of their research contributions. The range of publication venues and topics underscores a multidisciplinary approach within molecular biology and genetics.

Best Publications

  • Mutagenesis in Mammalian Cells Induced by Triple Helix Formation and Transcription-Coupled Repair

    Gan Wang;Michael M. Seidman;Peter M. Glazer

  • The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2.

    Patricia L Opresko;Marit Otterlei;Jesper Graakjær;Per Bruheim

  • A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells.

    Michael M. Seidman;Kathleen Dixon;Abdur Razzaque;Robert J. Zagursky

  • Targeted Mutagenesis in Mammalian Cells Mediated by Intracellular Triple Helix Formation

    Gan Wang;D. D. Levy;M. M. Seidman;P. M. Glazer

  • Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells

    Douglas E. Brash;Saraswathy Seetharam;Kenneth H. Kraemer;Michael M. Seidman

  • Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells

    Anders Bredberg;Kenneth H. Kraemer;Michael M. Seidman

  • Targeted gene knockout mediated by triple helix forming oligonucleotides.

    A. Majumdar;A. Khorlin;N. Dyatkina;F.-L. M. Lin

  • A histone-fold complex and FANCM form a conserved DNA remodeling complex to maintain genome stability

    Zhijiang Yan;Mathieu Delannoy;Chen Ling;Danielle Daee

  • The potential for gene repair via triple helix formation.

    Michael M. Seidman;Peter M. Glazer

  • Rearrangement and mutagenesis of a shuttle vector plasmid after passage in mammalian cells

    Abdur Razzaque;Hiroshi Mizusawa;Michael M. Seidman

  • DNA interstrand crosslink repair in mammalian cells: step by step

    Parameswary A Muniandy;Jia Liu;Alokes Majumdar;Su-ting Liu

  • The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks.

    Jing Huang;Shuo Liu;Marina A. Bellani;Arun Kalliat Thazhathveetil

  • Use of supF, an Escherichia coli tyrosine suppressor tRNA gene, as a mutagenic target in shuttle-vector plasmids.

    Kenneth H. Kraemer;Michael M. Seidman

  • Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents – A Potential Therapy for Cancer

    Nidal E Muvarak;Khadiza Chowdhury;Khadiza Chowdhury;Limin Xia;Carine Robert;Carine Robert

  • Triple-Helix Formation Induces Recombination in Mammalian Cells via a Nucleotide Excision Repair-Dependent Pathway

    A. Fawad Faruqi;Hirock J. Datta;Dana Carroll;Michael M. Seidman

  • CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes.

    Limin Xia;Limin Xia;Wenjie Huang;Marina Bellani;Michael M. Seidman

  • Unwinding of a DNA Triple Helix by the Werner and Bloom Syndrome Helicases

    Robert M. Brosh;Alokes Majumdar;Shital Desai;Ian D. Hickson

  • Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.

    M. M. Seidman;A. Bredberg;Saraswathy Seetharam;K. H. Kraemer

  • The asymmetric segregation of parental nucleosomes during chromosome replication

    Michael M. Seidman;Arnold J. Levine;Harold Weintraub

  • Linkage between Werner Syndrome Protein and the Mre11 Complex via Nbs1

    Wen-Hsing Cheng;Cayetano von Kobbe;Patricia L. Opresko;L. Matthew Arthur

Frequent Co-Authors

Kenneth H. Kraemer
Kenneth H. Kraemer National Institutes of Health
Peter M. Glazer
Peter M. Glazer Yale University
Paul S. Miller
Paul S. Miller Johns Hopkins University
Vilhelm A. Bohr
Vilhelm A. Bohr University of Copenhagen
Weidong Wang
Weidong Wang National Institutes of Health
Robert M. Brosh
Robert M. Brosh National Institutes of Health
Douglas E. Brash
Douglas E. Brash Yale University
Lei Li
Lei Li The University of Texas MD Anderson Cancer Center
Patricia L. Opresko
Patricia L. Opresko University of Pittsburgh
David M. Wilson
David M. Wilson AstraZeneca (United Kingdom)

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