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Molecular Biology

D-Index
48
Citations
9525
World Ranking
2680
National Ranking
1305

Patricia L. Opresko publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Patricia L. Opresko sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 126 publications — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Patricia L. Opresko D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Patricia L. Opresko sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 48 D-Index — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Patricia L. Opresko is affiliated with the University of Pittsburgh in the United States. Their research primarily falls within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus in the subfields of Molecular Biology, Physiology, Oncology, Aging, and Biotechnology.

The scientist's work spans several main topics, including:

  • Telomeres, Telomerase, and Senescence
  • DNA Repair Mechanisms
  • Advanced biosensing and bioanalysis techniques
  • DNA and Nucleic Acid Chemistry
  • RNA Interference and Gene Delivery
  • PARP inhibition in cancer therapy
  • CRISPR and Genetic Engineering

Patricia L. Opresko has published extensively in various scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Environmental and Molecular Mutagenesis
  • Nature Communications
  • Nucleic Acids Research
  • Biophysical Journal

Among the recent papers authored or co-authored by Opresko are:

  • New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary (2022, Aging)
  • Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening (2022, Nature Structural & Molecular Biology)
  • Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins (2022, Nature Communications)
  • Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs (2020, Nature Communications)
  • Roles for the 8-Oxoguanine DNA Repair System in Protecting Telomeres From Oxidative Stress (2021, Frontiers in Cell and Developmental Biology)

Their collaborations include frequent co-authors such as Ryan Barnes, Samantha L. Sanford, Ariana C. Detwiler, Mariarosaria De Rosa, and Marcel P. Bruchez. These collaborations have contributed to multiple papers across the highlighted research topics.

Best Publications

  • Human RecQ helicases in DNA repair, recombination, and replication.

    Deborah L. Croteau;Venkateswarlu Popuri;Patricia L. Opresko;Vilhelm A. Bohr

  • Telomere-binding Protein TRF2 Binds to and Stimulates the Werner and Bloom Syndrome Helicases

    Patricia L. Opresko;Cayetano von Kobbe;Jean-Philippe Laine;Jean-Philippe Laine;Jeanine Harrigan

  • The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2.

    Patricia L Opresko;Marit Otterlei;Jesper Graakjær;Per Bruheim

  • Cumulative Inflammatory Load Is Associated with Short Leukocyte Telomere Length in the Health, Aging and Body Composition Study

    Aoife O'Donovan;Aoife O'Donovan;Matthew S. Pantell;Eli Puterman;Firdaus S. Dhabhar

  • Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2

    Patricia L. Opresko;Jinshui Fan;Shamika Danzy;David M. Wilson

  • Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.

    Robert M. Brosh;Cayetano von Kobbe;Joshua A. Sommers;Parimal Karmakar

  • Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

    Patricia L. Opresko;Wen-Hsing Cheng;Cayetano von Kobbe;Jeanine A. Harrigan

  • POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.

    Patricia L. Opresko;Penelope A. Mason;Elaine R. Podell;Ming Lei

  • Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis

    Elise Fouquerel;Ryan P. Barnes;Shikhar Uttam;Simon C. Watkins

  • Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.

    Cayetano von Kobbe;Jeanine A. Harrigan;Alfred May;Patricia L. Opresko

  • Oxidative guanine base damage regulates human telomerase activity

    Elise Fouquerel;Justin Lormand;Arindam Bose;Hui-Ting Lee

  • The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase β

    Jeanine A. Harrigan;David M. Wilson;Rajendra Prasad;Patricia L. Opresko

  • The Werner Syndrome Protein Stimulates DNA Polymerase β Strand Displacement Synthesis via Its Helicase Activity

    Jeanine A. Harrigan;Patricia L. Opresko;Cayetano von Kobbe;Padmini S. Kedar

  • Telomere-associated aging disorders

    Patricia L. Opresko;Jerry W. Shay

  • Linkage between Werner Syndrome Protein and the Mre11 Complex via Nbs1

    Wen-Hsing Cheng;Cayetano von Kobbe;Patricia L. Opresko;L. Matthew Arthur

  • Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins.

    Cayetano von Kobbe;Parimal Karmakar;Lale Dawut;Patricia Opresko

  • POT1-TPP1 Regulates Telomeric Overhang Structural Dynamics

    Helen Hwang;Noah Buncher;Patricia L. Opresko;Sua Myong

  • Educational attainment and late life telomere length in the Health, Aging and Body Composition Study.

    Nancy Adler;Matthew S. Pantell;Aoife O’Donovan;Aoife O’Donovan;Elizabeth Blackburn

  • Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.

    Patricia L. Opresko;Jean-Philippe Laine;Jean-Philippe Laine;Robert M. Brosh;Michael M. Seidman

  • Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres

    Laura Garcia-Exposito;Elodie Bournique;Valérie Bergoglio;Arindam Bose

Frequent Co-Authors

Vilhelm A. Bohr
Vilhelm A. Bohr University of Copenhagen
Sua Myong
Sua Myong Johns Hopkins University
Robert M. Brosh
Robert M. Brosh National Institutes of Health
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Bruce A. Armitage
Bruce A. Armitage Carnegie Mellon University
Anne B. Newman
Anne B. Newman University of Pittsburgh
Richard M. Cawthon
Richard M. Cawthon University of Utah
Aoife O'Donovan
Aoife O'Donovan University of California, San Francisco
Tamara B. Harris
Tamara B. Harris National Institutes of Health
Susan Smith
Susan Smith New York University

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