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Biology and Biochemistry

D-Index
64
Citations
13964
World Ranking
9718
National Ranking
4277

Overview

Alessandro Vindigni is affiliated with Washington University in St. Louis in the United States and has a strong research focus within the fields of Biochemistry, Genetics, and Molecular Biology. The majority of their work is concentrated on Molecular Biology, with additional studies in Oncology, Immunology, Cancer Research, and Cell Biology.

Their research topics cover a variety of areas including DNA Repair Mechanisms, CRISPR and Genetic Engineering, Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, PARP inhibition in cancer therapy, Mitochondrial Function and Pathology, as well as Microtubule and mitosis dynamics.

Frequent coauthors in Vindigni's publications include:

  • Alice Meroni
  • Annabel Quinet
  • Emily Cybulla
  • Jessica Jackson
  • Sumedha Agashe

The most common venues publishing their work are:

  • Molecular Cell
  • The Journal of Cell Biology
  • Gynecologic Oncology
  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)

Significant recent papers by Alessandro Vindigni include:

  • "Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells" (2021, Molecular Cell)
  • "Leveraging the replication stress response to optimize cancer therapy" (2022, Nature reviews. Cancer)
  • "CARM1 regulates replication fork speed and stress response by stimulating PARP1" (2021, Molecular Cell)
  • "To skip or not to skip: choosing repriming to tolerate DNA damage" (2021, Molecular Cell)
  • "RAD51 bypasses the CMG helicase to promote replication fork reversal" (2023, Science)

Best Publications

  • Cobalt(II)‐Nitronyl Nitroxide Chains as Molecular Magnetic Nanowires

    Andrea Caneschi;Dante Gatteschi;Nikolia Lalioti;Claudio Sangregorio

  • Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells

    Ralph Zellweger;Damian Dalcher;Karun Mutreja;Matteo Berti

  • DNA repair is limiting for haematopoietic stem cells during ageing

    Anastasia Nijnik;Lisa Woodbine;Caterina Marchetti;Caterina Marchetti;Sara Dawson

  • Prevention of Vascular and Neural Dysfunction in Diabetic Rats by C-Peptide

    Y. Ido;A. Vindigni;K. Chang;L. Stramm

  • Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

    Matteo Berti;Arnab Ray Chaudhuri;Saravanabhavan Thangavel;Shivasankari Gomathinayagam

  • Single chain magnets: where to from here?

    Lapo Bogani;Lapo Bogani;Alessandro Vindigni;Roberta Sessoli;Dante Gatteschi

  • MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells

    Delphine Lemaçon;Jessica Jackson;Annabel Quinet;Joshua R. Brickner

  • DNA2 drives processing and restart of reversed replication forks in human cells

    Saravanabhavan Thangavel;Matteo Berti;Maryna Levikova;Cosimo Pinto

  • The Na+ Binding Site of Thrombin

    Enrico Di Cera;Enriqueta R. Guinto;Alessandro Vindigni;Quoc D. Dang

  • Replication stress: getting back on track.

    Matteo Berti;Matteo Berti;Alessandro Vindigni

  • Replication Fork Reversal: Players and Guardians

    Annabel Quinet;Delphine Lemaçon;Alessandro Vindigni

  • A topological mechanism for TRF2-enhanced strand invasion

    Simon Amiard;Michel Doudeau;Sébastien Pinte;Anaïs Poulet

  • An allosteric switch controls the procoagulant and anticoagulant activities of thrombin

    O D Dang;A Vindigni;E Di Cera

  • One-dimensional supramolecular organization of single-molecule magnets.

    Lollita Lecren;Wolfgang Wernsdorfer;Yang-Guang Li;Alessandro Vindigni

  • PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells

    Annabel Quinet;Stephanie Tirman;Stephanie Tirman;Jessica Jackson;Saša Šviković

  • The canted antiferromagnetic approach to single-chain magnets.

    Kevin Bernot;Javier Luzon;Roberta Sessoli;Alessandro Vindigni

  • The HRDC domain of BLM is required for the dissolution of double Holliday junctions.

    Leonard Wu;Kok Lung Chan;Christine Ralf;Douglas A Bernstein

  • DNA Fiber Analysis: Mind the Gap!

    Annabel Quinet;Denisse Carvajal-Maldonado;Delphine Lemacon;Alessandro Vindigni

  • Interaction of the Ku heterodimer with the DNA ligase IV/Xrcc4 complex and its regulation by DNA-PK.

    Silvia Costantini;Lisa Woodbine;Lucia Andreoli;Penny A. Jeggo

  • Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1

    Sudha Sharma;Joshua A. Sommers;Saba Choudhary;Jinnifer Korin Faulkner

Frequent Co-Authors

Opher Gileadi
Opher Gileadi Karolinska Institute
Roberta Sessoli
Roberta Sessoli University of Florence
Anton Simeonov
Anton Simeonov National Institutes of Health
Dante Gatteschi
Dante Gatteschi University of Florence
Andrea Caneschi
Andrea Caneschi University of Florence
Arturo Falaschi
Arturo Falaschi International Centre for Genetic Engineering and Biotechnology
Enrico Di Cera
Enrico Di Cera Saint Louis University
Massimo Lopes
Massimo Lopes University of Zurich
Claudio Sangregorio
Claudio Sangregorio National Research Council (CNR)
Ian D. Hickson
Ian D. Hickson University of Copenhagen

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