Stephen A. Ward

Overview

Best Publications

• Artemisinins target the SERCA of Plasmodium falciparum

  U. Eckstein-Ludwig;R. J. Webb;I. D. A. van Goethem;J. M. East

  1352
  Citations

• The molecular mechanism of action of artemisinin - the debate continues.

  Paul M. O’Neill;Victoria E. Barton;Stephen A. Ward

  775
  Citations

• Correction: Corrigendum: Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer’s Disease

  Omar Kassaar;Marta Pereira Morais;Suying Xu;Emily L. Adam

  498
  Citations

• A research agenda for malaria eradication: drugs.

  PL Alonso;Q Bassat

  406
  Citations

• 4-Aminoquinolines—Past, present, and future; A chemical perspective

  P M O'Neill;P G Bray;S R Hawley;S A Ward

  392
  Citations

• Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

  Patrick G. Bray;Michael P. Barrett;Stephen A. Ward;Harry P. de Koning

  314
  Citations

• Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7

  Hanafy M. Ismail;Victoria Barton;Matthew Phanchana;Sitthivut Charoensutthivarakul

  298
  Citations

• A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance

  Viswanathan Lakshmanan;Patrick G Bray;Dominik Verdier-Pinard;David J Johnson

  288
  Citations

• Access to Hematin: The Basis of Chloroquine Resistance

  Patrick G. Bray;Mathirut Mungthin;Robert G. Ridley;Stephen A. Ward

  288
  Citations

• Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance.

  Patrick G. Bray;Rowena E. Martin;Leann Tilley;Stephen A. Ward

  275
  Citations

• Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

  David J. Johnson;David J. Johnson;David A. Fidock;Mathirut Mungthin;Viswanathan Lakshmanan

  242
  Citations

• Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities.

  Stephen A Ward;Stephen A Ward;Thomas Walle;Thomas Walle;U Kristina Walle;U Kristina Walle;Grant R Wilkinson;Grant R Wilkinson

  238
  Citations

• Relationship between Antimalarial Drug Activity, Accumulation, and Inhibition of Heme Polymerization in Plasmodium falciparum In Vitro

  Shaun R. Hawley;Patrick G. Bray;Mathirut Mungthin;Jill D. Atkinson

  236
  Citations

• Chloroquine resistance before and after its withdrawal in Kenya

  Leah Mwai;Leah Mwai;Edwin Ochong;Abdi Abdirahman;Steven M Kiara

  230
  Citations

• Pharmacokinetics of primaquine in man: identification of the carboxylic acid derivative as a major plasma metabolite.

  GW Mihaly;SA Ward;G Edwards;ML Orme

  216
  Citations

• P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

  Jones K;Bray Pg;Khoo Sh;Davey Ra

  208
  Citations

• Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit

  Robert L. Clark;Tacey E.K. White;Sally A. Clode;Ian Gaunt

  208
  Citations

• Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum.

  Patrick G. Bray;Omar Janneh;Kaylene J. Raynes;Mathirut Mungthin

  205
  Citations

• Pharmacokinetics of halofantrine in man: effects of food and dose size.

  KA Milton;G Edwards;SA Ward;ML Orme

  204
  Citations

• Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance

  Stephen A Ward;Esperanca J P Sevene;Ian M Hastings;François Nosten;François Nosten

  200
  Citations