2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
2023 - Research.com Chemistry in Switzerland Leader Award
Reto Brun works mostly in the field of Pharmacokinetics, limiting it down to topics relating to Pharmacology and, in certain cases, Drug, as a part of the same area of interest. While working on this project, Reto Brun studies both Drug and Pharmacology. Antiprotozoal, Biological activity and Cytotoxicity are closely tied to his In vitro research. Reto Brun integrates Biochemistry and Microbiology in his research. In his research, Reto Brun performs multidisciplinary study on Microbiology and Biochemistry. He conducts interdisciplinary study in the fields of Immunology and Pathology through his works. Reto Brun combines Pathology and Immunology in his research. Reto Brun performs integrative study on Gene and Genetics. He performs integrative Genetics and Gene research in his work.
Reto Brun is investigating In vitro as part of his inquiry into Antiprotozoal, Cytotoxicity and IC50. Reto Brun performs multidisciplinary study in the fields of Biochemistry and Microbiology via his papers. In his research, Reto Brun undertakes multidisciplinary study on Microbiology and Biochemistry. In his study, Reto Brun carries out multidisciplinary Stereochemistry and Organic chemistry research. While working in this field, Reto Brun studies both Organic chemistry and Stereochemistry. His study connects Trypanosoma brucei rhodesiense and Immunology. His research brings together the fields of Immunology and Trypanosoma brucei rhodesiense. He performs multidisciplinary studies into Gene and Enzyme in his work. Reto Brun connects Enzyme with Gene in his research.
His Alkaloid research focuses on Stereochemistry and how it connects with Tetrahydroisoquinoline. His Tetrahydroisoquinoline study often links to related topics such as Stereochemistry. The In vitro portion of his research involves studies in Antiprotozoal, Cytotoxicity, IC50 and Biological activity. Cytotoxicity is closely attributed to In vitro in his work. His research on Biochemistry frequently connects to adjacent areas such as Antiprotozoal. Reto Brun connects Gene with Enzyme in his study. With his scientific publications, his incorporates both Enzyme and Gene. His research brings together the fields of Trypanosoma brucei rhodesiense and Immunology. Trypanosoma brucei rhodesiense is closely attributed to Immunology in his study.
In his research, Alkaloid is intimately related to Botany, which falls under the overarching field of Liana. His Botany research extends to the thematically linked field of Alkaloid. His Stereochemistry study frequently links to related topics such as Isoquinoline. His Isoquinoline study often links to related topics such as Stereochemistry. Many of his studies on Biochemistry involve topics that are commonly interrelated, such as Biological activity. His research on Biological activity often connects related topics like In vitro. His research brings together the fields of Antiprotozoal and In vitro. His Antiprotozoal study often links to related topics such as Biochemistry. Pharmacology and Pathology are two areas of study in which Reto Brun engages in interdisciplinary work.
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Spiroindolones, a Potent Compound Class for the Treatment of Malaria
Matthias Rottmann;Matthias Rottmann;Case McNamara;Bryan K.S. Yeung;Marcus C.S. Lee.
Antimalarial drug discovery: efficacy models for compound screening
David A. Fidock;Philip J. Rosenthal;Simon L. Croft;Reto Brun.
Nature Reviews Drug Discovery (2004)
Human African trypanosomiasis
Reto Brun;Johannes Blum;Francois Chappuis;Francois Chappuis;Christian Burri.
The Lancet (2010)
The Alamar Blue® assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro
B Räz;M Iten;Y Grether-Bühler;R Kaminsky.
Acta Tropica (1997)
Identification of an antimalarial synthetic trioxolane drug development candidate.
Jonathan L Vennerstrom;Sarah Arbe-Barnes;Reto Brun;Susan A Charman.
Kinetoplastids: related protozoan pathogens, different diseases
Ken Stuart;Reto Brun;Simon Croft;Alan Fairlamb.
Journal of Clinical Investigation (2008)
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
Susan A. Charman;Sarah Arbe-Barnes;Ian C. Bathurst;Reto Brun.
Proceedings of the National Academy of Sciences of the United States of America (2011)
Spirotetrahydro β-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria.
Bryan K S Yeung;Bin Zou;Matthias Rottmann;Suresh B Lakshminarayana.
Journal of Medicinal Chemistry (2010)
Antitrypanosomal and Antileishmanial Activities of Flavonoids and Their Analogues: In Vitro, In Vivo, Structure-Activity Relationship, and Quantitative Structure-Activity Relationship Studies
Deniz Tasdemir;Marcel Kaiser;Reto Brun;Vanessa Yardley.
Antimicrobial Agents and Chemotherapy (2006)
The Potential of Secondary Metabolites from Plants as Drugs or Leads Against Protozoan Neglected Diseases – Part I
T. J. Schmidt;S. A. Khalid;A. J. Romanha;T. Ma. Alves.
Current Medicinal Chemistry (2012)
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