World's Best Scientists 2026 revealed!
Award Badge
Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Chemistry

D-Index
93
Citations
30352
World Ranking
1799
National Ranking
37

Biology and Biochemistry

D-Index
100
Citations
39910
World Ranking
1503
National Ranking
33

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Reto Brun is affiliated with the University of Basel in Switzerland and contributes to research primarily in the fields of medicine and chemistry, with a focus on organic chemistry and epidemiology. Their work encompasses infectious diseases, public health, environmental and occupational health, and molecular biology.

Their research topics are centered around trypanosoma species and their implications, leishmaniasis studies, and HIV/AIDS drug development and treatment. In addition, they investigate the synthesis and biological activity of compounds, synthesis and characterization of heterocyclic compounds, and conduct biochemical and molecular research.

Reto Brun has published in several academic venues. The most frequent venues include:

  • UNC Libraries
  • European Journal of Medicinal Chemistry
  • Journal of Medicinal Chemistry
  • OPAL (Open@LaTrobe) (La Trobe University)
  • CHIMIA International Journal for Chemistry

Frequent coauthors collaborating with Reto Brun are:

  • David W. Boykin
  • Richard R. Tidwell
  • Tanja Wenzler
  • Arlene S. Bridges
  • Kirsten Gillingwater

Recent publications by Reto Brun include:

  • Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles, 2021, European Journal of Medicinal Chemistry
  • Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis, 2022, Journal of Medicinal Chemistry
  • Investigation of the effect of structure modification of furamidine on the DNA minor groove binding and antiprotozoal activity, 2023, European Journal of Medicinal Chemistry
  • Synthesis and Antiprotozoal Activity of Cationic 1,4-Diphenyl-1 H -1,2,3-triazoles, 2020, OPAL (Open@LaTrobe) (La Trobe University)
  • New antiparasitic flexible triaryl diamidines, their prodrugs and aza analogues: Synthesis, in vitro and in vivo biological evaluation, and molecular modelling studies, 2021, European Journal of Medicinal Chemistry

Best Publications

  • Spiroindolones, a Potent Compound Class for the Treatment of Malaria

    Matthias Rottmann;Matthias Rottmann;Case McNamara;Bryan K.S. Yeung;Marcus C.S. Lee

  • Antimalarial drug discovery: efficacy models for compound screening

    David A. Fidock;Philip J. Rosenthal;Simon L. Croft;Reto Brun

  • Human African trypanosomiasis

    Reto Brun;Johannes Blum;Francois Chappuis;Francois Chappuis;Christian Burri

  • The Alamar Blue® assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

    B Räz;M Iten;Y Grether-Bühler;R Kaminsky

  • Identification of an antimalarial synthetic trioxolane drug development candidate.

    Jonathan L Vennerstrom;Sarah Arbe-Barnes;Reto Brun;Susan A Charman

  • Kinetoplastids: related protozoan pathogens, different diseases

    Ken Stuart;Reto Brun;Simon Croft;Alan Fairlamb

  • Antitrypanosomal and Antileishmanial Activities of Flavonoids and Their Analogues: In Vitro, In Vivo, Structure-Activity Relationship, and Quantitative Structure-Activity Relationship Studies

    Deniz Tasdemir;Marcel Kaiser;Reto Brun;Vanessa Yardley

  • Spirotetrahydro β-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria.

    Bryan K S Yeung;Bin Zou;Matthias Rottmann;Suresh B Lakshminarayana

  • Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

    Susan A. Charman;Sarah Arbe-Barnes;Ian C. Bathurst;Reto Brun

  • Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

    M P Barrett;D W Boykin;R Brun;R R Tidwell

  • Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness

    Els Torreele;Bernadette Bourdin Trunz;David Tweats;David Tweats;Marcel Kaiser;Marcel Kaiser

  • Trypanosoma evansi and T. equiperdum: distribution, biology, treatment and phylogenetic relationship (a review)

    Reto Brun;Hermann Hecker;Zhao-Rong Lun

  • SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.

    Robert T. Jacobs;Bakela Nare;Stephen A. Wring;Matthew D. Orr

  • The Potential of Secondary Metabolites from Plants as Drugs or Leads Against Protozoan Neglected Diseases – Part I

    T. J. Schmidt;S. A. Khalid;A. J. Romanha;T. Ma. Alves

  • A simple monophasic medium for axenic culture of hemoflagellates.

    Randy L. Berens;Reto Brun;Stuart M. Krassner

  • Eflornithine for the treatment of human African trypanosomiasis.

    Christian Burri;Reto Brun

  • Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.

    Gerhard Bringmann;Michael Dreyer;Johan H. Faber;Petur Weihe Dalsgaard

  • Evaluation of African medicinal plants for their in vitro trypanocidal activity

    F. Freiburghaus;R. Kaminsky;M.H.H. Nkunya;R. Brun

  • The phenomenon of treatment failures in Human African Trypanosomiasis

    Reto Brun;Reto Schumacher;Cecile Schmid;Christina Kunz

  • Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

    Kisaburo Nagamune;Tomoyoshi Nozaki;Yusuke Maeda;Kazuhito Ohishi

  • 45 – Human African Trypanosomiasis

    Christian Burri;François Chappuis;Reto Brun

Frequent Co-Authors

Marcel Kaiser
Marcel Kaiser Swiss Tropical and Public Health Institute
Gerhard Bringmann
Gerhard Bringmann University of Würzburg
Sergio Wittlin
Sergio Wittlin Swiss Tropical and Public Health Institute
David W. Boykin
David W. Boykin Georgia State University
Ian H. Gilbert
Ian H. Gilbert University of Dundee
Richard R. Tidwell
Richard R. Tidwell University of North Carolina at Chapel Hill
W. David Wilson
W. David Wilson Georgia State University
Matthias Hamburger
Matthias Hamburger University of Basel
Pascal Mäser
Pascal Mäser Swiss Tropical and Public Health Institute
Michael P. Barrett
Michael P. Barrett University of Glasgow

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Reto Brun

Trending Scientists

Recently Published Articles