Harry P. de Koning

Overview

Best Publications

• The animal trypanosomiases and their chemotherapy: a review.

  Federica Giordani;Liam J. Morrison;Tim G. Rowan;Harry P. De Koning

  422
  Citations

• Drugs and drug resistance in African trypanosomiasis.

  Vincent Delespaux;Harry P. de Koning

  369
  Citations

• Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

  Patrick G. Bray;Michael P. Barrett;Stephen A. Ward;Harry P. de Koning

  314
  Citations

• Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story

  Nicola Baker;Harry P. de Koning;Pascal Mäser;Pascal Mäser;David Horn

  290
  Citations

• Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species

  Chatchawan Changtam;Harry P. de Koning;Hasan Ibrahim;M. Sohail Sajid

  224
  Citations

• Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.

  Enock Matovu;Mhairi L. Stewart;Federico Geiser;Reto Brun

  210
  Citations

• Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals.

  H P De Koning

  209
  Citations

• Nucleobase transporters (review).

  H de Koning;G Diallinas

  201
  Citations

• Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy.

  Harry P. de Koning;Daniel J. Bridges;Richard J.S. Burchmore

  187
  Citations

• Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

  Hideo Imamura;Tim Downing;Tim Downing;Frederik Van den Broeck;Mandy J Sanders

  182
  Citations

• Transporters in African trypanosomes: role in drug action and resistance.

  Harry P de Koning

  179
  Citations

• Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes.

  Nicola Baker;Lucy Glover;Jane C. Munday;David Aguinaga Andrés

  175
  Citations

• Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

  Jane C. Munday;Anthonius A. Eze;Anthonius A. Eze;Nicola Baker;Lucy Glover

  158
  Citations

• Loss of the High-Affinity Pentamidine Transporter Is Responsible for High Levels of Cross-Resistance between Arsenical and Diamidine Drugs in African Trypanosomes

  Daniel J. Bridges;Matthew K. Gould;Barbara Nerima;Pascal Mäser

  151
  Citations

• Diamidines for human African trypanosomiasis.

  Mary F Paine;Michael Zhuo Wang;Claudia N Generaux;David W Boykin

  140
  Citations

• Different Substrate Recognition Motifs of Human and Trypanosome Nucleobase Transporters SELECTIVE UPTAKE OF PURINE ANTIMETABOLITES

  Lynsey J. M. Wallace;Denise Candlish;Harry P. De Koning

  140
  Citations

• Aquaporin 2 Mutations in Trypanosoma brucei gambiense Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol

  Fabrice E. Graf;Philipp Ludin;Philipp Ludin;Tanja Wenzler;Tanja Wenzler;Marcel Kaiser;Marcel Kaiser

  135
  Citations

• Characterization of a nucleoside/proton symporter in procyclic trypanosoma brucei brucei

  Harry P. de Koning;Christopher J. Watson;Simon M. Jarvis

  132
  Citations

• The Trypanocide Diminazene Aceturate Is Accumulated Predominantly through the TbAT1 Purine Transporter: Additional Insights on Diamidine Resistance in African Trypanosomes

  Harry P. de Koning;Laura F. Anderson;Mhairi Stewart;Richard J. S. Burchmore

  116
  Citations

• Characterization of the choline carrier of Plasmodium falciparum : a route for the selective delivery of novel antimalarial drugs

  Giancarlo A. Biagini;Erica M. Pasini;Ruth Hughes;Harry P. De Koning

  113
  Citations