World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
61
Citations
13094
World Ranking
3063
National Ranking
381

Research.com Recognitions

  • 2017 - Fellow of the Royal Society of Edinburgh

Overview

David Horn is affiliated with the University of Dundee in the United Kingdom. Their research primarily focuses on fields related to Medicine and Biochemistry, Genetics and Molecular Biology, contributing significantly to the understanding of parasitic diseases caused by trypanosomatids.

The scientist's recent publications include the following:

  • Anti-trypanosomatid drug discovery: progress and challenges, 2022, Nature Reviews Microbiology
  • Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes, 2021, Nature Microbiology
  • Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes, 2020, Journal of Biological Chemistry
  • A profile of research on the parasitic trypanosomatids and the diseases they cause, 2022, PLoS neglected tropical diseases
  • Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs, 2020, PLoS Pathogens

Their frequent co-authors include:

  • Michele Tinti (15 collaborations)
  • Joana Faria (11 collaborations)
  • Mark C. Field (8 collaborations)
  • Sebastian Hutchinson (6 collaborations)
  • Susan Wyllie (5 collaborations)

Their work is often published in notable venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory) with 9 publications
  • Nature Communications with 4 publications
  • PLoS neglected tropical diseases with 3 publications
  • Nature Reviews Microbiology with 2 publications
  • PLoS Pathogens with 2 publications

David Horn's research spans several main topics, notably:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Insect symbiosis and bacterial influences
  • CRISPR and Genetic Engineering
  • Biochemical and Molecular Research
  • Lysosomal Storage Disorders Research
  • Chromosomal and Genetic Variations

Their research subfields include Epidemiology, Molecular Biology, Public Health, Environmental and Occupational Health, Insect Science, and Physiology.

David Horn has also contributed to academic dissemination through book publishing, having one book titled Para-Site-Seeing published in 2020 by University of Dundee eBooks.

In recognition of their scientific contributions, they were awarded the Fellowship of the Royal Society of Edinburgh in 2017.

Best Publications

  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Daniella C. Bartholomeu;Daniel Nilsson

  • The genome of the kinetoplastid parasite, Leishmania major.

    Alasdair C. Ivens;Christopher S. Peacock;Elizabeth A. Worthey;Lee Murphy

  • Comparative genomics of trypanosomatid parasitic protozoa.

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Gaëlle Blandin;Matthew Berriman

  • High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

    Sam Alsford;Daniel J. Turner;Samson O. Obado;Alejandro Sanchez-Flores

  • Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

    Mark C. Field;David Horn;Alan H. Fairlamb;Michael A. J. Ferguson

  • High-throughput decoding of antitrypanosomal drug efficacy and resistance

    Sam Alsford;Sabine E. Eckert;Nicola Baker;Lucy Glover

  • Antigenic variation in African trypanosomes

    David Horn

  • Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei

    Binny M. Mony;Paula MacGregor;Alasdair Ivens;Federico Rojas

  • A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei

    Vincent P. Alibu;Lilian Storm;Simon Haile;Christine Clayton

  • Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects.

    Sam Alsford;Taemi Kawahara;Lucy Glover;David Horn

  • A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei

    David Horn;George A.M. Cross

  • Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei.

    Sam Alsford;David Horn

  • Molecular mechanisms underlying the control of antigenic variation in African trypanosomes

    David Horn;Richard McCulloch

  • Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

    Jane C. Munday;Anthonius A. Eze;Anthonius A. Eze;Nicola Baker;Lucy Glover

  • Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

    Susan Wyllie;Stephen Brand;Michael Thomas;Manu De Rycker

  • A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation

    Sam Alsford;Taemi Kawahara;Cyril Isamah;David Horn

  • Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6

    Nicola Baker;Sam Alsford;David Horn

  • RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome.

    Shane R. Wilkinson;David Horn;S.Radhika Prathalingam;John M. Kelly

  • NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions.

    Kelly N. DuBois;Sam Alsford;Jennifer M. Holden;Johanna Buisson

  • Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes

    Lucy Glover;Richard McCulloch;David Horn

Frequent Co-Authors

Mark C. Field
Mark C. Field University of Dundee
Pascal Mäser
Pascal Mäser Swiss Tropical and Public Health Institute
Harry P. de Koning
Harry P. de Koning University of Glasgow
David S. Latchman
David S. Latchman University College London
John M. Kelly
John M. Kelly London School of Hygiene & Tropical Medicine
Michael P. Barrett
Michael P. Barrett University of Glasgow
Ian H. Gilbert
Ian H. Gilbert University of Dundee
Michael A. J. Ferguson
Michael A. J. Ferguson University of Dundee
Alan H. Fairlamb
Alan H. Fairlamb University of Dundee
George A. M. Cross
George A. M. Cross Rockefeller University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Genetics is a dynamic field that opens doors to diverse careers in healthcare and research. Exploring online degrees can greatly expand your options, whether you’re interested in advancing clinically or moving into healthcare leadership.

For those considering parallel healthcare roles, nursing remains a popular choice. It’s now even more accessible thanks to nursing program no teas requirements, which can streamline your entry into the field. If you’re seeking affordable leadership roles, numerous most affordable online mha programs in Healthcare Administration can help you progress to managerial positions within medical or research settings.

Fast-track programs are also available if you want to enter the workforce sooner. Consider flexible online lpn programs to quickly secure a footing in healthcare environments related to genetics. Meanwhile, for professionals aspiring to the highest academic qualifications, cheapest online nursing phd programs allow you to pursue advanced research or academic roles with a focus on cost-effective study.

Navigating these educational pathways can enhance your understanding of genetics while maximizing career flexibility in the ever-evolving health sciences sector.

Best Scientists Citing David Horn

Trending Scientists