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Molecular Biology

D-Index
91
Citations
43384
World Ranking
714
National Ranking
56

Research.com Recognitions

  • 2010 - Fellow of the Royal Society of Edinburgh

Overview

Jeremy C. Mottram is affiliated with the University of York in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with significant contributions to Epidemiology, Public Health, Environmental and Occupational Health, Molecular Biology, Cell Biology, and Parasitology.

The scientist's research focuses on several main topics including:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Biochemical and Molecular Research
  • Parasites and Host Interactions
  • Lysosomal Storage Disorders Research
  • Cellular transport and secretion
  • Peptidase Inhibition and Analysis

Jeremy C. Mottram has published numerous papers in multiple venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • Nature Communications
  • Zenodo (CERN European Organization for Nuclear Research)
  • Trends in Parasitology

Recent notable papers by Jeremy C. Mottram include:

  • New Drugs for Human African Trypanosomiasis: A Twenty First Century Success Story, 2020, Tropical Medicine and Infectious Disease
  • Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival, 2021, Nature Communications
  • Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors, 2020, Nature Microbiology
  • Essential roles for deubiquitination in Leishmania life cycle progression, 2020, PLoS Pathogens
  • Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice, 2021, Nature Communications

Frequent co-authors collaborating with Jeremy C. Mottram include:

  • Carolina Moura Costa Catta-Preta
  • Anthony J. Wilkinson
  • Eva Gluenz
  • Rachel Neish
  • Vincent Geoghegan

In 2010, Jeremy C. Mottram was awarded the title of Fellow of the Royal Society of Edinburgh.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Daniella C. Bartholomeu;Daniel Nilsson

  • The genome of the kinetoplastid parasite, Leishmania major.

    Alasdair C. Ivens;Christopher S. Peacock;Elizabeth A. Worthey;Lee Murphy

  • Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

    Jane M. Carlton;Robert . Hirt;Joana C. Silva;Arthur L. Delcher

  • Comparative genomics of trypanosomatid parasitic protozoa.

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Gaëlle Blandin;Matthew Berriman

  • Comparative genomic analysis of three Leishmania species that cause diverse human disease

    Christopher S Peacock;Kathy Seeger;David Harris;Lee Murphy

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania

    Matthew B. Rogers;James D. Hilley;Nicholas J. Dickens;Jon Wilkes

  • Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

    Tim Downing;Hideo Imamura;Saskia Decuypere;Taane G. Clark

  • Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi.

    Marilyn Parsons;Marilyn Parsons;Elizabeth A Worthey;Pauline N Ward;Jeremy C Mottram

  • Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets

    Graham H. Coombs;Daniel E. Goldberg;Michael Klemba;Colin Berry

  • Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

    Shilpi Khare;Advait S. Nagle;Agnes Biggart;Yin H. Lai

  • Leishmania mexicana Cysteine Proteinase-Deficient Mutants Have Attenuated Virulence for Mice and Potentiate a Th1 Response

    James Alexander;Graham H. Coombs;Jeremy C. Mottram

  • Cysteine peptidases as virulence factors of Leishmania

    Jeremy C Mottram;Graham H Coombs;James Alexander

  • Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors

    Marie Knockaert;N. Gray;E. Damiens;Y.-T. Chang

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

    J C Mottram;A E Souza;J E Hutchison;R Carter

  • Protein kinases as drug targets in trypanosomes and Leishmania.

    Christina Naula;Marilyn Parsons;Marilyn Parsons;Jeremy C. Mottram

  • Endosome Sorting and Autophagy Are Essential for Differentiation and Virulence of Leishmania major

    Sébastien Besteiro;Roderick A.M. Williams;Lesley S. Morrison;Graham H. Coombs

Frequent Co-Authors

Graham H. Coombs
Graham H. Coombs University of Strathclyde
Luiz Juliano
Luiz Juliano Federal University of Sao Paulo
Maria A. Juliano
Maria A. Juliano Federal University of Sao Paulo
Morten Meldal
Morten Meldal University of Copenhagen
Michael P. Barrett
Michael P. Barrett University of Glasgow
James Alexander
James Alexander Centers for Disease Control and Prevention
Marilyn Parsons
Marilyn Parsons University of Washington
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Evelina Gatti
Evelina Gatti Aix-Marseille University
Petr Volf
Petr Volf Charles University

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