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D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10724
World Ranking
12719
National Ranking
987

R. A. John Challiss publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where R. A. John Challiss sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 236 publications — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

R. A. John Challiss D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where R. A. John Challiss sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 59 D-Index — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

R. A. John Challiss is affiliated with the University of Leicester in the United Kingdom. Their research primarily focuses on biochemistry, genetics, molecular biology, and neuroscience, with particular emphasis on molecular biology and cellular and molecular neuroscience.

The scientist's main topics of work include receptor mechanisms and signaling, neuroscience and neuropharmacology research, nicotinic acetylcholine receptors study, monoclonal and polyclonal antibodies research, neuropeptides and animal physiology, neuroinflammation and neurodegeneration mechanisms, and protein kinase regulation and GTPase signaling.

Significant publications by R. A. John Challiss cover various aspects of receptor biology and pharmacology. Some recent papers include:

  • Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs, 2020, Nature Chemical Biology
  • β1-adrenoceptor-stimulated lactate production in cultured astrocytes is predominantly glycogen-independent, 2020, Biochemical Pharmacology
  • Acetylcholine receptors (muscarinic) in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Acetylcholine receptors (muscarinic) in GtoPdb v.2021.2, 2021, IUPHAR/BPS Guide to Pharmacology CITE
  • Acetylcholine receptors (muscarinic) in GtoPdb v.2021.3, 2021, IUPHAR/BPS Guide to Pharmacology CITE

Frequent publication venues for their work include:

  • IUPHAR/BPS Guide to Pharmacology CITE
  • Biochemical Pharmacology
  • Nature Chemical Biology

Collaborations are a component of their research, working often with Sophie J. Bradley, Arthur Christopoulos, Andrew B. Tobin, N.J.M. Birdsall, and David A. Brown.

Best Publications

  • Neuronal Ca2+ stores : activation and function

    Peter B. Simpson;R.A. John Challiss;Stefan R. Nahorski

  • Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences

    Stefan R. Nahorski;C. Ian Ragan;R.A.John Challiss

  • Mass measurements of inositol(1,4,5)trisphosphate in rat cerebral cortex slices using a radioreceptor assay: Effects of neurotransmitters and depolarization

    R.A. John Challiss;Ian H. Batty;Stefan R. Nahorski

  • Intracellular signalling. Receptor-specific messenger oscillations.

    Mark S. Nash;Kenneth W. Young;R. A. John Challiss;Stefan R. Nahorski

  • Nitric oxide is a volume transmitter regulating postsynaptic excitability at a glutamatergic synapse.

    Joern R. Steinert;Cornelia Kopp-Scheinpflug;Claire Baker;R.A. John Challiss

  • Differential Regulation of Muscarinic Acetylcholine Receptor-sensitive Polyphosphoinositide Pools and Consequences for Signaling in Human Neuroblastoma Cells

    Gary B. Willars;Stefan R. Nahorski;R.A. John Challiss

  • Heterogeneity of [3H]inositol 1,4,5-trisphosphate binding sites in adrenal-cortical membranes. Characterization and validation of a radioreceptor assay.

    R A J Challiss;E R Chilvers;A L Willcocks;S R Nahorski

  • Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen-activated protein kinase

    Jennifer L. Albert;John P. Boyle;Jonathan A. Roberts;R. A. John Challiss

  • Non-visual GRKs: are we seeing the whole picture?

    Jonathon M. Willets;R.A.John Challiss;Stefan R. Nahorski

  • Phosphorus-31 NMR magnetization-transfer measurements of ATP turnover during steady-state isometric muscle contraction in the rat hind limb in vivo

    K.M. Brindle;M.J. Blackledge;R.A.J. Challiss;G.K. Radda

  • Increased Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Expression Mediates Intrinsic Airway Smooth Muscle Hypercontractility in Asthma

    Amanda Sutcliffe;Fay Hollins;Edith Gomez;Ruth Saunders

  • The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats

    G. Dimitriadis;M. Parry-Billings;S. Bevan;B. Leighton

  • Determinants of Metabotropic Glutamate Receptor-5-mediated Ca2+ and Inositol 1,4,5-Trisphosphate Oscillation Frequency RECEPTOR DENSITY VERSUS AGONIST CONCENTRATION

    Mark S. Nash;Michael J. Schell;Peter J. Atkinson;Neil R. Johnston

  • Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slices.

    E D Kennedy;R A J Challiss;C I Ragan;S R Nahorski

  • New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor

    Robert A Wilcox;William U Primrose;Stefan R Nahorski;R.A.John Challiss

  • Group-I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways.

    Sukhwinder Thandi;Jonathan L. Blank;R. A. John Challiss

  • Mechanisms Underlying the Neuronal Calcium Sensor-1-evoked Enhancement of Exocytosis in PC12 Cells

    Schuichi Koizumi;Patrizia Rosa;Gary B. Willars;R.A. John Challiss

  • The effect of prostaglandins E1, E2 and F2α and indomethacin on the sensitivity of glycolysis and glycogen synthesis to insulin in stripped soleus muscles of the rat

    B Leighton;L Budohoski;F J Lozeman;R A J Challiss

  • Substrate cycles: their role in improving sensitivity in metabolic control

    E.A. Newsholme;R.A.J. Challiss;B. Crabtree

  • G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype.

    Elizabeth C Akam;R A John Challiss;Stefan R Nahorski

Frequent Co-Authors

Stefan R. Nahorski
Stefan R. Nahorski University of Leicester
Edwin R. Chilvers
Edwin R. Chilvers Imperial College London
Andrew B. Tobin
Andrew B. Tobin University of Glasgow
Ian D. Forsythe
Ian D. Forsythe University of Leicester
Jürgen Wess
Jürgen Wess National Institutes of Health
Mark A. Giembycz
Mark A. Giembycz University of Calgary
Christopher E. Brightling
Christopher E. Brightling University of Leicester
Martin D. Bootman
Martin D. Bootman The Open University
Richard M. Eglen
Richard M. Eglen Corning (United States)
Elizabeth Scarr
Elizabeth Scarr University of Melbourne

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