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Biology and Biochemistry

D-Index
59
Citations
10191
World Ranking
12765
National Ranking
994

Overview

Andrew B. Tobin is affiliated with the University of Glasgow in the United Kingdom. Their research spans multiple interdisciplinary fields, primarily focusing on biochemistry, genetics, molecular biology, medicine, and neuroscience. The scientist's work encompasses various subfields including molecular biology, cellular and molecular neuroscience, physiology, public health, environmental and occupational health, and spectroscopy.

The primary topics explored by Andrew B. Tobin include receptor mechanisms and signaling, neuroscience and neuropharmacology research, neuropeptides and animal physiology, nicotinic acetylcholine receptors study, prion diseases and protein misfolding, computational drug discovery methods, and malaria research and control.

Frequent publication venues for Tobin's work highlight contributions in bioRxiv (Cold Spring Harbor Laboratory), ACS Pharmacology & Translational Science, Journal of Biological Chemistry, IUPHAR/BPS Guide to Pharmacology CITE, and Nature.

Selected recent papers authored or co-authored by Andrew B. Tobin are:

  • "Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival," 2021, Nature Communications
  • "Combinatorial expression of GPCR isoforms affects signalling and drug responses," 2020, Nature
  • "From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer's disease," 2021, Cell
  • "Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity," 2020, Cell Chemical Biology
  • "Therapeutic Opportunities and Challenges in Targeting the Orphan G Protein-Coupled Receptor GPR35," 2020, ACS Pharmacology & Translational Science

Andrew B. Tobin frequently collaborates with several co-authors, including Graeme Milligan, Arthur Christopoulos, Sophie J. Bradley, Patrick M. Sexton, and Céline Valant. These collaborations contribute to a strong network in their fields of study.

Best Publications

  • Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum

    Lev Solyakov;Jean Halbert;Jean Halbert;Mahmood M Alam;Jean-Phillipe Semblat;Jean-Phillipe Semblat

  • The experimental power of FR900359 to study Gq-regulated biological processes

    Ramona Schrage;Anna Lena Schmitz;Evelyn Gaffal;Suvi Annala

  • Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

    Andrew B. Tobin;Adrian J. Butcher;Kok Choi Kong

  • G-protein-coupled receptor phosphorylation: where, when and by whom.

    A B Tobin

  • The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

    Brian D Hudson;Bharat Shimpukade;Amanda E Mackenzie;Adrian J Butcher

  • Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.

    Adrian J. Butcher;Rudi Prihandoko;Kok Choi Kong;Phillip McWilliams

  • β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

    Susanne Nuber;Ulrike Zabel;Kristina Lorenz;Kristina Lorenz;Andreas Nuber

  • The Pharmacology and Function of Receptors for Short-Chain Fatty Acids.

    Daniele Bolognini;Andrew B Tobin;Graeme Milligan;Catherine E Moss

  • Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion

    Mahmood M Alam;Lev Solyakov;Andrew R Bottrill;Christian Flueck

  • Identification and preliminary characterization of protein-cysteine farnesyltransferase.

    V Manne;D Roberts;A Tobin;E O'Rourke

  • DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo

    Karen J Thompson;Elham Khajehali;Sophie J Bradley;Jovana S Navarrete;Jovana S Navarrete

  • Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias.

    Karen J. Gregory;Nathan E. Hall;Andrew B. Tobin;Patrick M. Sexton

  • Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling *

    Elisa Alvarez-Curto;Asuka Inoue;Asuka Inoue;Laura Jenkins;Sheikh Zahir Raihan

  • The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner.

    Benoit Poulin;Adrian J. Butcher;Phillip McWilliams;Julie-Myrtille Bourgognon

  • Protein kinases of malaria parasites: an update.

    Christian Doerig;Oliver Billker;Timothy Haystead;Pushkar Sharma

  • Antimuscarinic antibodies in Sjögren's syndrome: Where are we, and where are we going?

    Luke Dawson;Andrew Tobin;Peter Smith;Tom Gordon

  • Desensitization of cell signalling mediated by phosphoinositidase C

    Richard J.H. Wojcikiewicz;Andrew B. Tobin;Stefan R. Nahorski

  • Rapid agonist-mediated phosphorylation of m3-muscarinic receptors revealed by immunoprecipitation.

    A B Tobin;S R Nahorski

  • Post-translational protein modifications in malaria parasites

    Christian D Doerig;Julian C Rayner;Artur Scherf;Andrew B Tobin

  • Phosphorylation and regulation of a G protein–coupled receptor by protein kinase CK2

    Ignacio Torrecilla;Elizabeth J. Spragg;Benoit Poulin;Phillip J. McWilliams

Frequent Co-Authors

Graeme Milligan
Graeme Milligan University of Glasgow
Christian Doerig
Christian Doerig RMIT University
Arthur Christopoulos
Arthur Christopoulos Monash University
Patrick M. Sexton
Patrick M. Sexton Monash University
Stefan R. Nahorski
Stefan R. Nahorski University of Leicester
Trond Ulven
Trond Ulven University of Copenhagen
R. A. John Challiss
R. A. John Challiss University of Leicester
Jürgen Wess
Jürgen Wess National Institutes of Health
Martin J. Lohse
Martin J. Lohse ISAR Bioscience Institute
M. Madan Babu
M. Madan Babu St. Jude Children's Research Hospital

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