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Asuka Inoue

Asuka Inoue

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
17308
World Ranking
8163
National Ranking
547

Overview

Asuka Inoue is affiliated with Tohoku University in Japan and has produced a significant body of research in the fields of Biochemistry, Genetics, and Molecular Biology, particularly focusing on Molecular Biology and Cellular and Molecular Neuroscience.

The primary areas of Inoue's work include Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Protein Kinase Regulation and GTPase Signaling, Pancreatic function and diabetes, Monoclonal and Polyclonal Antibodies Research, Chemokine receptors and signaling, and Mass Spectrometry Techniques and Applications.

Inoue has published frequently in several scientific venues, with a notable number of papers appearing in bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, The FASEB Journal, Journal of Biological Chemistry, and Cell Reports.

Recent publications by Inoue include the following:

  • Structure of the neurotensin receptor 1 in complex with β-arrestin 1, 2020, Nature
  • Activation of the GLP-1 receptor by a non-peptidic agonist, 2020, Nature
  • Structural insights into differences in G protein activation by family A and family B GPCRs, 2020, Science
  • Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling, 2021, Cell Reports
  • Insights into distinct signaling profiles of the µOR activated by diverse agonists, 2022, Nature Chemical Biology

Inoue has collaborated extensively with various scientists, frequently working with Kouki Kawakami, Junken Aoki, Ryoji Kise, Osamu Nureki, and Tatsuya Ikuta.

Best Publications

  • LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing.

    Xiaoqin Ye;Kotaro Hama;James J. A. Contos;Brigitte Anliker

  • Non-cell-autonomous control of vascular stem cell fate by a CLE peptide/receptor system

    Yuki Hirakawa;Hidefumi Shinohara;Yuki Kondo;Asuka Inoue

  • Illuminating G-Protein-Coupling Selectivity of GPCRs.

    Asuka Inoue;Asuka Inoue;Francesco Raimondi;Francois Marie Ngako Kadji;Gurdeep Singh

  • Two pathways for lysophosphatidic acid production.

    Junken Aoki;Asuka Inoue;Asuka Inoue;Shinichi Okudaira;Shinichi Okudaira

  • TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

    Asuka Inoue;Jun Ishiguro;Hajime Kitamura;Naoaki Arima

  • Lack of beta-arrestin signaling in the absence of active G proteins

    Manuel Grundmann;Nicole Merten;Davide Malfacini;Asuka Inoue;Asuka Inoue

  • Structure of the neurotensin receptor 1 in complex with β-arrestin 1.

    Weijiao Huang;Matthieu Masureel;Qianhui Qu;John Janetzko

  • The experimental power of FR900359 to study Gq-regulated biological processes

    Ramona Schrage;Anna Lena Schmitz;Evelyn Gaffal;Suvi Annala

  • Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis

    Thomas J. Cahill;Alex R.B. Thomsen;Jeffrey T. Tarrasch;Bianca Plouffe

  • The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

    Shigetomo Fukuhara;Szandor Simmons;Shunsuke Kawamura;Asuka Inoue

  • Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells.

    Qingwen Wan;Najeah Okashah;Asuka Inoue;Rony Nehmé

  • Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

    Hiroshi Nishimasu;Shinichi Okudaira;Kotaro Hama;Emiko Mihara

  • Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family.

    Junken Aoki;Asuka Inoue;Kumiko Makide;Naoya Saiki

  • Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK.

    Morgan O’Hayre;Kelsie Eichel;Silvia Avino;Silvia Avino;Xuefeng Zhao;Xuefeng Zhao;Xuefeng Zhao

  • Targeting GLP-1 receptor trafficking to improve agonist efficacy.

    Ben Jones;Teresa Buenaventura;Nisha Kanda;Pauline Chabosseau

  • Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MS

    Michiyo Okudaira;Asuka Inoue;Akira Shuto;Keita Nakanaga

  • Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase.

    Keiichi Iwanami;Isao Matsumoto;Isao Matsumoto;Yoko Tanaka-Watanabe;Asuka Inoue

  • Novel lysophosphoplipid receptors: their structure and function.

    Kumiko Makide;Kumiko Makide;Akiharu Uwamizu;Yuji Shinjo;Jun Ishiguro

  • LPA‐producing enzyme PA‐PLA1α regulates hair follicle development by modulating EGFR signalling

    Asuka Inoue;Asuka Inoue;Naoaki Arima;Jun Ishiguro;Glenn D Prestwich

  • Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling *

    Elisa Alvarez-Curto;Asuka Inoue;Asuka Inoue;Laura Jenkins;Sheikh Zahir Raihan

Frequent Co-Authors

Junken Aoki
Junken Aoki Tohoku University
Osamu Nureki
Osamu Nureki University of Tokyo
J. Silvio Gutkind
J. Silvio Gutkind University of California, San Diego
Gabriele M. König
Gabriele M. König University of Bonn
Tomohiko Ohwada
Tomohiko Ohwada University of Tokyo
Evi Kostenis
Evi Kostenis University of Bonn
Hiroyuki Arai
Hiroyuki Arai University of Tokyo
Terence E. Hébert
Terence E. Hébert McGill University
Guy A. Rutter
Guy A. Rutter Imperial College London
So Iwata
So Iwata Kyoto University

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