Junken Aoki focuses on Lysophosphatidic acid, Biochemistry, Cell biology, Autotaxin and Receptor. His work deals with themes such as Lysophosphatidylcholine, Cancer research, Lipid signaling and Cell growth, which intersect with Lysophosphatidic acid. His Molecular biology research extends to the thematically linked field of Biochemistry.
His work in Cell biology covers topics such as Unsaturated fatty acid which are related to areas like Saturated fatty acid. His Autotaxin research incorporates elements of Autocrine signalling, Cancer cell, Immunology, Lysophospholipids and Motility. His work focuses on many connections between Receptor and other disciplines, such as Transfection, that overlap with his field of interest in Agonist, Cell migration and Glioma.
His main research concerns Lysophosphatidic acid, Biochemistry, Cell biology, Autotaxin and Receptor. His study looks at the relationship between Lysophosphatidic acid and fields such as Cancer research, as well as how they intersect with chemical problems. His Biochemistry research focuses on Molecular biology and how it connects with Gene.
His study in Signal transduction and Intracellular falls under the purview of Cell biology. His Autotaxin research is multidisciplinary, relying on both Neuropathic pain, Autocrine signalling, Immunology, Pathogenesis and Motility. Junken Aoki interconnects Stereochemistry and Pharmacology in the investigation of issues within Receptor.
The scientist’s investigation covers issues in Receptor, Cell biology, Lysophosphatidic acid, G protein-coupled receptor and Autotaxin. Junken Aoki has included themes like Transforming growth factor, Pharmacology and Binding site in his Receptor study. His Cell biology research includes themes of Endothelial stem cell, In situ hybridization, Dendritic cell, Lymphatic system and Cell type.
Lysophosphatidic acid is the topic of his studies on Biochemistry and Internal medicine. His G protein-coupled receptor study integrates concerns from other disciplines, such as Ligand, Biophysics, Inverse agonist and Heterotrimeric G protein, G protein. His Autotaxin research integrates issues from Phenotype, Gene, Zebrafish and Pathogenesis.
His primary scientific interests are in Cell biology, Receptor, G protein-coupled receptor, Lysophosphatidic acid and Internal medicine. His research in Cell biology intersects with topics in Agonist, Partial agonist, Mechanism of action and Lymphatic system. His Receptor research incorporates themes from Endogeny and Binding site.
His G protein-coupled receptor research is multidisciplinary, relying on both Phenotype, HEK 293 cells, Transmembrane domain and Heterotrimeric G protein, G protein. Particularly relevant to LPAR1 is his body of work in Lysophosphatidic acid. His Internal medicine research integrates issues from Endocrinology, Cauda equina and Neuropathic pain.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The Transcriptional Landscape of the Mammalian Genome
P. Carninci;T. Kasukawa;S. Katayama;J. Gough.
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production.
Makiko Umezu-Goto;Yasuhiro Kishi;Akitsu Taira;Kotaro Hama.
Journal of Cell Biology (2002)
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
Thomas M. McIntyre;Aaron V. Pontsler;Adriana R. Silva;Andy St. Hilaire.
Proceedings of the National Academy of Sciences of the United States of America (2003)
LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing.
Xiaoqin Ye;Kotaro Hama;James J. A. Contos;Brigitte Anliker.
Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid
Koji Bandoh;Junken Aoki;Hiroyuki Hosono;Susumu Kobayashi.
Journal of Biological Chemistry (1999)
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein.
Kenichi Takahashi;Hiroyuki Nakanishi;Masako Miyahara;Kenji Mandai.
Journal of Cell Biology (1999)
Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways
Junken Aoki;Akitsu Taira;Yasukazu Takanezawa;Yasuhiro Kishi.
Journal of Biological Chemistry (2002)
Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid
Masayuki Tanaka;Shinichi Okudaira;Yasuhiro Kishi;Ryunosuke Ohkawa.
Journal of Biological Chemistry (2006)
Two pathways for lysophosphatidic acid production.
Junken Aoki;Asuka Inoue;Asuka Inoue;Shinichi Okudaira;Shinichi Okudaira.
Biochimica et Biophysica Acta (2008)
TGFα shedding assay: an accurate and versatile method for detecting GPCR activation
Asuka Inoue;Jun Ishiguro;Hajime Kitamura;Naoaki Arima.
Nature Methods (2012)
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