D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 98 Citations 30,629 413 World Ranking 1106 National Ranking 64

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Junken Aoki focuses on Lysophosphatidic acid, Biochemistry, Cell biology, Autotaxin and Receptor. His work deals with themes such as Lysophosphatidylcholine, Cancer research, Lipid signaling and Cell growth, which intersect with Lysophosphatidic acid. His Molecular biology research extends to the thematically linked field of Biochemistry.

His work in Cell biology covers topics such as Unsaturated fatty acid which are related to areas like Saturated fatty acid. His Autotaxin research incorporates elements of Autocrine signalling, Cancer cell, Immunology, Lysophospholipids and Motility. His work focuses on many connections between Receptor and other disciplines, such as Transfection, that overlap with his field of interest in Agonist, Cell migration and Glioma.

His most cited work include:

  • The Transcriptional Landscape of the Mammalian Genome (2876 citations)
  • Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. (774 citations)
  • Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist (500 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Lysophosphatidic acid, Biochemistry, Cell biology, Autotaxin and Receptor. His study looks at the relationship between Lysophosphatidic acid and fields such as Cancer research, as well as how they intersect with chemical problems. His Biochemistry research focuses on Molecular biology and how it connects with Gene.

His study in Signal transduction and Intracellular falls under the purview of Cell biology. His Autotaxin research is multidisciplinary, relying on both Neuropathic pain, Autocrine signalling, Immunology, Pathogenesis and Motility. Junken Aoki interconnects Stereochemistry and Pharmacology in the investigation of issues within Receptor.

He most often published in these fields:

  • Lysophosphatidic acid (43.01%)
  • Biochemistry (39.19%)
  • Cell biology (36.65%)

What were the highlights of his more recent work (between 2018-2021)?

  • Receptor (34.32%)
  • Cell biology (36.65%)
  • Lysophosphatidic acid (43.01%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Receptor, Cell biology, Lysophosphatidic acid, G protein-coupled receptor and Autotaxin. Junken Aoki has included themes like Transforming growth factor, Pharmacology and Binding site in his Receptor study. His Cell biology research includes themes of Endothelial stem cell, In situ hybridization, Dendritic cell, Lymphatic system and Cell type.

Lysophosphatidic acid is the topic of his studies on Biochemistry and Internal medicine. His G protein-coupled receptor study integrates concerns from other disciplines, such as Ligand, Biophysics, Inverse agonist and Heterotrimeric G protein, G protein. His Autotaxin research integrates issues from Phenotype, Gene, Zebrafish and Pathogenesis.

Between 2018 and 2021, his most popular works were:

  • Illuminating G-Protein-Coupling Selectivity of GPCRs. (122 citations)
  • Conformational transitions of a neurotensin receptor 1-Gi1complex. (66 citations)
  • GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites. (52 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Cell biology, Receptor, G protein-coupled receptor, Lysophosphatidic acid and Internal medicine. His research in Cell biology intersects with topics in Agonist, Partial agonist, Mechanism of action and Lymphatic system. His Receptor research incorporates themes from Endogeny and Binding site.

His G protein-coupled receptor research is multidisciplinary, relying on both Phenotype, HEK 293 cells, Transmembrane domain and Heterotrimeric G protein, G protein. Particularly relevant to LPAR1 is his body of work in Lysophosphatidic acid. His Internal medicine research integrates issues from Endocrinology, Cauda equina and Neuropathic pain.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Transcriptional Landscape of the Mammalian Genome

P. Carninci;T. Kasukawa;S. Katayama;J. Gough.
Science (2005)

3849 Citations

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production.

Makiko Umezu-Goto;Yasuhiro Kishi;Akitsu Taira;Kotaro Hama.
Journal of Cell Biology (2002)

950 Citations

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist

Thomas M. McIntyre;Aaron V. Pontsler;Adriana R. Silva;Andy St. Hilaire.
Proceedings of the National Academy of Sciences of the United States of America (2003)

658 Citations

LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing.

Xiaoqin Ye;Kotaro Hama;James J. A. Contos;Brigitte Anliker.
Nature (2005)

618 Citations

Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid

Koji Bandoh;Junken Aoki;Hiroyuki Hosono;Susumu Kobayashi.
Journal of Biological Chemistry (1999)

613 Citations

Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein.

Kenichi Takahashi;Hiroyuki Nakanishi;Masako Miyahara;Kenji Mandai.
Journal of Cell Biology (1999)

612 Citations

Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways

Junken Aoki;Akitsu Taira;Yasukazu Takanezawa;Yasuhiro Kishi.
Journal of Biological Chemistry (2002)

482 Citations

Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid

Masayuki Tanaka;Shinichi Okudaira;Yasuhiro Kishi;Ryunosuke Ohkawa.
Journal of Biological Chemistry (2006)

480 Citations

Two pathways for lysophosphatidic acid production.

Junken Aoki;Asuka Inoue;Asuka Inoue;Shinichi Okudaira;Shinichi Okudaira.
Biochimica et Biophysica Acta (2008)

446 Citations

TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

Asuka Inoue;Jun Ishiguro;Hajime Kitamura;Naoaki Arima.
Nature Methods (2012)

347 Citations

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