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Biology and Biochemistry

D-Index
90
Citations
28801
World Ranking
2441
National Ranking
1296

Overview

Andrew J. Morris is affiliated with the University of Kentucky in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on several subfields including Molecular Biology, Health, Toxicology and Mutagenesis, Cell Biology, Environmental Chemistry, and Epidemiology.

The scientist's work covers a range of main topics such as:

  • Per- and polyfluoroalkyl substances research
  • Sphingolipid Metabolism and Signaling
  • Toxic Organic Pollutants Impact
  • Endoplasmic Reticulum Stress and Disease
  • Adipose Tissue and Metabolism
  • ATP Synthase and ATPases Research
  • Air Quality and Health Impacts

Recent notable papers include:

  • The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans, 2020, Journal of Clinical Investigation
  • Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression, 2020, Nature Communications
  • Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells, 2021, Cell Reports
  • Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK-SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue, 2021, Cells
  • Roles for lysophosphatidic acid signaling in vascular development and disease, 2020, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Frequent co-authors in their publications include Susan S. Smyth, Terry D. Hinds, Pan Deng, M. Abdul Mottaleb, and Clark Sims.

The scientist's publications have appeared repeatedly in venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), The FASEB Journal, arXiv (Cornell University), and ISEE Conference Abstracts.

Best Publications

  • Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation

    Akira Honda;Masahiro Nogami;Takeaki Yokozeki;Masakazu Yamazaki

  • Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

    William C. Colley;Tsung-Chang Sung;Richard Roll;John Jenco

  • Human ADP-ribosylation Factor-activated Phosphatidylcholine-specific Phospholipase D Defines a New and Highly Conserved Gene Family

    Scott M. Hammond;Yelena M. Altshuller;Tsung Chang Sung;Simon A. Rudge

  • Characterization of Two Alternately Spliced Forms of Phospholipase D1 ACTIVATION OF THE PURIFIED ENZYMES BY PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE, ADP-RIBOSYLATION FACTOR, AND RHO FAMILY MONOMERIC GTP-BINDING PROTEINS AND PROTEIN KINASE C-α

    Scott M. Hammond;John M. Jenco;Shigeru Nakashima;Karen Cadwallader

  • Physiological regulation of G protein-linked signaling.

    Andrew J. Morris;Craig C. Malbon

  • Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins.

    John M. Jenco;Andrew Rawlingson;Brenda Daniels;Andrew J. Morris

  • Bayesian refinement of association signals for 14 loci in 3 common diseases.

    Julian B. Maller;Gilean McVean;Gilean McVean;Jake Byrnes;Damjan Vukcevic

  • Synucleins are a novel class of substrates for G protein-coupled receptor kinases.

    Alexey N. Pronin;Andrew J. Morris;Andrei Surguchov;Jeffrey L. Benovic

  • ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

    Martin J. Law;Karen M. Lower;Hsiao P.J. Voon;Jim R. Hughes

  • XX sex chromosome complement promotes atherosclerosis in mice.

    Yasir AlSiraj;Xuqi Chen;Sean E. Thatcher;Ryan E. Temel

  • Mutagenesis of phospholipase D defines a superfamily including a trans-Golgi viral protein required for poxvirus pathogenicity.

    Tsung Chang Sung;Rachel L. Roper;Yue Zhang;Simon A. Rudge

  • THE PLECKSTRIN HOMOLOGY DOMAIN OF PHOSPHOLIPASE C-DELTA 1 BINDS WITH HIGH AFFINITY TO PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE IN BILAYER MEMBRANES

    Pilar Garcia;Rakesh Gupta;Shefali Shah;Andrew J. Morris

  • Mammalian phospholipase D structure and regulation.

    Michael A Frohman;Tsung-Chang Sung;Andrew J Morris

  • Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

    Brett H. Herzog;Jianxin Fu;Jianxin Fu;Stephen J. Wilson;Paul R. Hess

  • Structural basis of substrate discrimination and integrin binding by autotaxin

    Jens Hausmann;Satwik Kamtekar;Evangelos Christodoulou;Jacqueline E Day

  • Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network

    Ye Guang Chen;Anirban Siddhanta;Cary D. Austin;Scott M. Hammond

  • piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling.

    Huiyan Huang;Qun Gao;Xiaoxue Peng;Seok Yong Choi;Seok Yong Choi

  • Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

    Sifan Chen;Sifan Chen;Ayana Henderson;Michael C. Petriello;Michael C. Petriello;Kymberleigh A. Romano

  • Measurement of Phospholipase D Activity

    Andrew J. Morris;Michael A. Frohman;JoAnne Engebrecht

  • Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells

    Nicolas Vitale;Anne‐Sophie Caumont;Sylvette Chasserot‐Golaz;Guangwei Du

Frequent Co-Authors

Michael A. Frohman
Michael A. Frohman Stony Brook University
Bernhard Hennig
Bernhard Hennig University of Kentucky
Jon S. Thorson
Jon S. Thorson University of Kentucky
Mariusz Z. Ratajczak
Mariusz Z. Ratajczak University of Louisville
Janina Ratajczak
Janina Ratajczak University of Louisville
James C. Hower
James C. Hower University of Kentucky
Lisa A. Cassis
Lisa A. Cassis University of Kentucky
Viswanathan Natarajan
Viswanathan Natarajan University of Illinois at Chicago
Sidney W. Whiteheart
Sidney W. Whiteheart University of Kentucky
B. Mark Evers
B. Mark Evers University of Kentucky

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