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Biology and Biochemistry

D-Index
68
Citations
14996
World Ranking
7876
National Ranking
202

Overview

Giovanni Maga is affiliated with the National Research Council (CNR) in Italy and specializes in research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, including Molecular Biology, Infectious Diseases, Organic Chemistry, Public Health, Environmental and Occupational Health, and Epidemiology.

The focus of Giovanni Maga's research covers a range of important topics, notably:

  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • SARS-CoV-2 and COVID-19 Research
  • Mosquito-borne diseases and control
  • Viral gastroenteritis research and epidemiology
  • Viral Infections and Immunology Research
  • HIV Research and Treatment

They have contributed to multiple publications, with frequent appearances in the following venues:

  • European Journal of Medicinal Chemistry
  • International Journal of Molecular Sciences
  • ChemMedChem
  • Nucleic Acids Research
  • Cancers

Giovanni Maga's recent papers include:

  • "A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping," 2020, published in Cells
  • "A Structural View at SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping," 2020, published in Preprints.org
  • "DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins," 2020, published in European Journal of Medicinal Chemistry
  • "Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins," 2020, published in Frontiers in Chemistry
  • "Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses," 2021, published in ChemMedChem

Their frequent collaborators include:

  • Emmanuele Crespan
  • Elena Dreassi
  • Anna Garbelli
  • Valentina Riva
  • Maurizio Zazzi

Best Publications

  • Proliferating cell nuclear antigen (PCNA): a dancer with many partners.

    Giovanni Maga;Ulrich Hübscher

  • Eukaryotic DNA polymerases.

    Ulrich Hübscher;Giovanni Maga;Silvio Spadari

  • Specific Structural Determinants Are Responsible for the Antioxidant Activity and the Cell Cycle Effects of Resveratrol

    Lucia A. Stivala;Monica Savio;Federico Carafoli;Paola Perucca

  • A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping.

    Maria Romano;Alessia Ruggiero;Flavia Squeglia;Giovanni Maga

  • 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins

    Giovanni Maga;Giuseppe Villani;Emmanuele Crespan;Ursula Wimmer

  • The RNA helicase, nucleotide 5'-triphosphatase, and RNA 5'-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core.

    Delphine Benarroch;Barbara Selisko;Giada A. Locatelli;Giovanni Maga

  • Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide.

    Rino Ragno;Antonio Coluccia;Giuseppe La Regina;Gabriella De Martino

  • Indolylarylsulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: New Cyclic Substituents at Indole-2-carboxamide

    Giuseppe La Regina;Antonio Coluccia;Andrea Brancale;Francesco Piscitelli

  • DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene

    J S Hoffmann;M J Pillaire;G Maga;V Podust

  • Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: Past, present, and future perspectives

    Giuseppe Campiani;Anna Ramunno;Giovanni Maga;Vito Nacci

  • L-thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth.

    Silvio Spadari;Giovanni Maga;Federico Focher;Giovanni Ciarrocchi

  • Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.

    Giovanni Maga;Mario Amacker;Nancy Ruel;Ulrich Hübscher

  • Human DNA Polymerase λ Functionally and Physically Interacts with Proliferating Cell Nuclear Antigen in Normal and Translesion DNA Synthesis

    Giovanni Maga;Giuseppe Villani;Kristijan Ramadan;Igor Shevelev

  • Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins

    B. Pascucci;G. Maga;U. Hübscher;M. Bjoras

  • A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells.

    R. Fotedar;R. Mossi;P. Fitzgerald;T. Rousselle

  • Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.

    Annalaura Brai;Roberta Fazi;Cristina Tintori;Claudio Zamperini

  • Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent

    G Campiani;F Aiello;M Fabbrini;E Morelli

  • DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading.

    Giovanni Maga;Manuel Stucki;Silvio Spadari;Ulrich Hübscher

  • Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners.

    Isabelle Frouin;Giovanni Maga;Marco Denegri;Federica Riva

  • Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions.

    Kristijan Ramadan;Giovanni Maga;Igor V Shevelev;Igor V Shevelev;Giuseppe Villani

Frequent Co-Authors

Maurizio Botta
Maurizio Botta University of Siena
Ulrich Hübscher
Ulrich Hübscher University of Zurich
Silvia Schenone
Silvia Schenone University of Genoa
Fabrizio Manetti
Fabrizio Manetti University of Siena
José A. Esté
José A. Esté Autonomous University of Barcelona
Ettore Novellino
Ettore Novellino University of Naples Federico II
Romano Silvestri
Romano Silvestri Sapienza University of Rome
Giuseppe Campiani
Giuseppe Campiani University of Siena
Fausto Baldanti
Fausto Baldanti University of Pavia
Marino Artico
Marino Artico Sapienza University of Rome

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