D-Index & Metrics Best Publications
Microbiology
Belgium
2022

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 110 Citations 47,476 634 World Ranking 51 National Ranking 2
Medicine D-index 110 Citations 48,549 668 World Ranking 2383 National Ranking 22

Research.com Recognitions

Awards & Achievements

2022 - Research.com Microbiology in Belgium Leader Award

2010 - Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson for his landmark discoveries in anti-HIV medications, including nucleotide analogues, and inventions or co-inventions of several approved drugs for anti-viral therapy.

1994 - Fellow of the American Association for the Advancement of Science (AAAS)

1989 - Member of Academia Europaea

Overview

What is he best known for?

The fields of study he is best known for:

  • Virus
  • Enzyme
  • Gene

Erik De Clercq focuses on Virology, Virus, Stereochemistry, Molecular biology and Biochemistry. His Virology research includes themes of Reverse transcriptase and Immunology. His Reverse transcriptase research incorporates themes from Nevirapine and Drug resistance.

His study brings together the fields of Microbiology and Virus. His research in Stereochemistry intersects with topics in Biological activity, Structure–activity relationship, Chemical synthesis and Enzyme inhibitor. His studies deal with areas such as Cell culture, Integrase, DNA, Chemokine and CC chemokine receptors as well as Molecular biology.

His most cited work include:

  • Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds (1426 citations)
  • Therapeutic options for the 2019 novel coronavirus (2019-nCoV). (811 citations)
  • Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives (670 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Stereochemistry, Virology, Virus, Biochemistry and Reverse transcriptase. His Stereochemistry research incorporates elements of Biological activity, Structure–activity relationship and Chemical synthesis. Erik De Clercq interconnects Bicyclic molecule, Enzyme inhibitor and Reverse-transcriptase inhibitor in the investigation of issues within Chemical synthesis.

Erik De Clercq has researched Virology in several fields, including Molecular biology and In vitro. Erik De Clercq does research in Virus, focusing on Vesicular stomatitis virus specifically. His Reverse transcriptase study combines topics from a wide range of disciplines, such as Mutant and Enzyme.

He most often published in these fields:

  • Stereochemistry (36.79%)
  • Virology (35.50%)
  • Virus (19.80%)

What were the highlights of his more recent work (between 2010-2021)?

  • Stereochemistry (36.79%)
  • Reverse transcriptase (13.61%)
  • Virology (35.50%)

In recent papers he was focusing on the following fields of study:

Erik De Clercq mostly deals with Stereochemistry, Reverse transcriptase, Virology, Mutant and Combinatorial chemistry. As a part of the same scientific study, Erik De Clercq usually deals with the Stereochemistry, concentrating on Structure–activity relationship and frequently concerns with Cell culture. His Reverse transcriptase study integrates concerns from other disciplines, such as Nevirapine, EC50 and Potency.

The study incorporates disciplines such as Pharmacology and Nucleoside in addition to Virology. His Mutant research includes elements of Mutation, Molecular biology, Docking and Enzyme. His research on Virus concerns the broader Immunology.

Between 2010 and 2021, his most popular works were:

  • Therapeutic options for the 2019 novel coronavirus (2019-nCoV). (811 citations)
  • Approved Antiviral Drugs over the Past 50 Years (524 citations)
  • Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends (157 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Virus
  • Gene

Erik De Clercq mainly focuses on Stereochemistry, Virology, Reverse transcriptase, Nucleoside Reverse Transcriptase Inhibitor and Diarylpyrimidines. The various areas that he examines in his Stereochemistry study include Combinatorial chemistry, Delavirdine and Structure–activity relationship. His studies in Virology integrate themes in fields like Immunology, Pharmacology and Nucleoside.

His Reverse transcriptase research is multidisciplinary, incorporating perspectives in EC50, Biological activity, Docking and Strain. His Pyrimidine research is multidisciplinary, incorporating elements of Aryl and In vitro. His Virus research integrates issues from Favipiravir and BCX4430.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels;Jan Balzarini;Masanori Baba;Robert Snoeck.
Journal of Virological Methods (1988)

2327 Citations

Angiogenesis : regulators and clinical applications

Sandra Liekens;Erik De Clercq;Johan Neyts.
Biochemical Pharmacology (2001)

1089 Citations

A novel selective broad-spectrum anti-DNA virus agent.

Erik De Clercq;Antonin Holý;Ivan Rosenberg;Takashi Sakuma.
Nature (1986)

1045 Citations

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Rudi Pauwels;Koen Andries;Jan Desmyter;Dominique Schols.
Nature (1990)

1040 Citations

Toward improved anti-HIV chemotherapy: therapeutic strategies for intervention with HIV infections.

Erik De Clercq.
Journal of Medicinal Chemistry (1995)

888 Citations

Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4

Dominique Schols;Sofie Struyf;Jo Van Damme;José A. Esté.
Journal of Experimental Medicine (1997)

817 Citations

Therapeutic options for the 2019 novel coronavirus (2019-nCoV).

Guangdi Li;Erik De Clercq.
Nature Reviews Drug Discovery (2020)

811 Citations

Approved Antiviral Drugs over the Past 50 Years

Erik De Clercq;Guangdi Li;Guangdi Li.
Clinical Microbiology Reviews (2016)

799 Citations

Antiviral agents active against influenza A viruses

Erik De Clercq.
Nature Reviews Drug Discovery (2006)

780 Citations

Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV.

Erik De Clercq.
International Journal of Antimicrobial Agents (2009)

722 Citations

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