What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Integrase, Viral replication, Molecular biology, Virology and Virus.
His studies in Integrase integrate themes in fields like Mutation, Virus Integration, HIV integration and Integrase inhibitor.
His Viral replication study combines topics in areas such as Reverse transcriptase, Polymerase chain reaction, Biochemistry, DNA and Nuclear transport.
His Molecular biology research is multidisciplinary, relying on both PSIP1, Regulation of gene expression, Gene, Transduction and Viral vector.
Zeger Debyser has researched Virology in several fields, including Cell culture, Small molecule and Binding site.
His work deals with themes such as In vitro, Mechanism of action and Recombinant virus, which intersect with Virus.
His most cited work include:
- HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells (576 citations)
- LEDGF/p75 Is Essential for Nuclear and Chromosomal Targeting of HIV-1 Integrase in Human Cells (430 citations)
- Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication (355 citations)
What are the main themes of his work throughout his whole career to date?
Zeger Debyser mainly focuses on Virology, Integrase, Molecular biology, Cell biology and Viral replication.
His Virology study combines topics from a wide range of disciplines, such as Reverse transcriptase and Gene.
His Integrase course of study focuses on Stereochemistry and Structure–activity relationship.
His work focuses on many connections between Molecular biology and other disciplines, such as Viral vector, that overlap with his field of interest in Genetic enhancement, Transduction and Gene expression.
His Cell biology research is multidisciplinary, incorporating perspectives in Alpha-synuclein and Bioluminescence imaging.
His Viral replication research includes themes of Virus Integration and Nuclear transport.
He most often published in these fields:
- Virology (31.58%)
- Integrase (30.92%)
- Molecular biology (16.78%)
What were the highlights of his more recent work (between 2015-2021)?
- Integrase (30.92%)
- Virology (31.58%)
- Cell biology (14.80%)
In recent papers he was focusing on the following fields of study:
Integrase, Virology, Cell biology, Chromatin and Computational biology are his primary areas of study.
Zeger Debyser combines subjects such as Virus, Viral replication, Nuclear transport and Provirus with his study of Integrase.
He has included themes like Virus Integration and Molecular biology in his Viral replication study.
His work on Retrovirology is typically connected to Doxycycline as part of general Virology study, connecting several disciplines of science.
His Cell biology study integrates concerns from other disciplines, such as Cell culture, Protein domain, PSIP1 and Binding domain.
Zeger Debyser interconnects Insertional mutagenesis, Small Molecule Libraries, Genetic enhancement and Transduction in the investigation of issues within Computational biology.
Between 2015 and 2021, his most popular works were:
- Preclinical Evaluation of a P2X7 Receptor–Selective Radiotracer: PET Studies in a Rat Model with Local Overexpression of the Human P2X7 Receptor and in Nonhuman Primates (54 citations)
- LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV (51 citations)
- Proceedings of the Frontiers of Retrovirology Conference 2016 (33 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Integrase, Virology, Chromatin, Cell biology and Provirus.
His Integrase research is multidisciplinary, incorporating elements of Plasma protein binding, Virus, Viral replication, Computational biology and Drug discovery.
His studies deal with areas such as Nuclear transport and Virus Integration as well as Viral replication.
His research in Virology intersects with topics in Record locking, Viral rebound and Treatment interruption.
His Cell biology research includes elements of Binding domain, PSIP1, Molecular biology, Fusion protein and Leukemia.
His Provirus research also works with subjects such as
- Transcription which is related to area like Regulation of gene expression and Gene silencing,
- HIV integration that intertwine with fields like Virus latency, Acquired immunodeficiency syndrome and Integrase inhibitor.
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