Nouri Neamati mostly deals with Integrase, Stereochemistry, Biochemistry, Small molecule and Molecular model. Nouri Neamati has included themes like Pharmacophore, Docking, Pharmacology and Enzyme in his Integrase study. His Stereochemistry research incorporates elements of Potency, Chemical synthesis, In vivo and Active site.
His research in Biochemistry intersects with topics in Cancer cell and Cancer. Nouri Neamati combines subjects such as Molecular biology and STAT3, Signal transduction, Cell biology with his study of Small molecule. His Molecular model study combines topics from a wide range of disciplines, such as Quantitative structure–activity relationship, Binding site and Biological activity.
Integrase, Stereochemistry, Biochemistry, Enzyme and Cancer research are his primary areas of study. When carried out as part of a general Integrase research project, his work on Hiv 1 integrase is frequently linked to work in Integrase inhibitor, therefore connecting diverse disciplines of study. His Stereochemistry study integrates concerns from other disciplines, such as Biological activity, Structure–activity relationship and Chemical synthesis.
His Enzyme research includes elements of Lentivirus, Viral replication and Nucleotidyltransferase. The concepts of his Cancer research study are interwoven with issues in Cancer cell, Cancer, Pancreatic cancer, Cell culture and Cisplatin. His studies deal with areas such as Drug and Drug discovery as well as Virology.
Nouri Neamati focuses on Cancer research, Cancer, Pancreatic cancer, Pharmacology and Stereochemistry. His Cancer research study incorporates themes from Cancer cell, Prostate, Prostate cancer and Cell growth. His Cancer research integrates issues from Cell, Traditional medicine and Immunology.
His Pharmacology study combines topics in areas such as Cell culture and Kinase activity. His Stereochemistry research incorporates elements of Integrase, Chelation and Active site. His Integrase research is included under the broader classification of Biochemistry.
Nouri Neamati mainly focuses on Biochemistry, Cancer, Integrase, Cell culture and Viral replication. His Biochemistry study frequently links to related topics such as Cancer therapy. His research integrates issues of Oxidative phosphorylation, Protein disulfide-isomerase and Immunology in his study of Cancer.
His study in Integrase is interdisciplinary in nature, drawing from both Plasma protein binding, Transcription factor, Peptide sequence, Peptide and Carboxamide. His work deals with themes such as Active site, Enzyme and Pharmacophore, Natural product, Stereochemistry, which intersect with Viral replication. His specific area of interest is Stereochemistry, where Nouri Neamati studies Thiazole.
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Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism
Divya Pathania;Melissa Millard;Nouri Neamati.
Advanced Drug Delivery Reviews (2009)
Identification of N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4
Qian Zhao;Liying Ma;Shibo Jiang;Hong Lu.
Virology (2005)
Small Molecule Inhibitors of CXCR4
Bikash Debnath;Shili Xu;Fedora Grande;Antonio Garofalo.
Theranostics (2013)
Rational Design and Synthesis of Novel Dimeric Diketoacid-Containing Inhibitors of HIV-1 Integrase: Implication for Binding to Two Metal Ions on the Active Site of Integrase
Ya Qiu Long;Xiao Hua Jiang;Raveendra Dayam;Tino Sanchez.
Journal of Medicinal Chemistry (2004)
Role of the CXCL8-CXCR1/2 axis in cancer and inflammatory diseases
Helen Ha;Bikash Debnath;Nouri Neamati.
Theranostics (2017)
In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide.
Yanbin Ji;Subhabrata Majumder;Melissa Millard;Radhika Borra.
Journal of the American Chemical Society (2013)
Structural Determinants for HIV-1 Integrase Inhibition by β-Diketo Acids
Christophe Marchand;Xuechun Zhang;Godwin C.G. Pais;Kiriana Cowansage.
Journal of Biological Chemistry (2002)
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors
Erik Serrao;Srinivas Odde;Kavya Ramkumar;Nouri Neamati.
Retrovirology (2009)
Protein disulfide isomerase: A promising target for cancer therapy
Shili Xu;Saranya Sankar;Nouri Neamati.
Drug Discovery Today (2014)
Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
Jinxia Deng;Tino Sanchez;Laith Q. Al-Mawsawi;Raveendra Dayam.
Bioorganic & Medicinal Chemistry (2007)
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