2023 - Research.com Chemistry in Australia Leader Award
His scientific interests lie mostly in Cyclotide, Cyclotides, Biochemistry, Cystine knot and Stereochemistry. His Cyclotide study introduces a deeper knowledge of Peptide. The study incorporates disciplines such as Drug, Scaffold, Helix, Nicotinic acetylcholine receptor and In vivo in addition to Peptide.
The Cyclotides study combines topics in areas such as Combinatorial chemistry, Violaceae, Botany and Biological activity. David J. Craik has researched Cystine knot in several fields, including Plant protein, Protein folding, Structural motif, Beta sheet and Computational biology. His biological study spans a wide range of topics, including Peptide bond, Conotoxin and Native chemical ligation, Cysteine.
David J. Craik focuses on Biochemistry, Peptide, Stereochemistry, Cyclotides and Cyclotide. His Peptide research is multidisciplinary, relying on both Protein structure, Biophysics and Membrane. His research in Stereochemistry intersects with topics in Conotoxin, Molecule and Cysteine.
His study in Cyclotides is interdisciplinary in nature, drawing from both Violaceae, Structural motif, Combinatorial chemistry, Cystine knot and Computational biology. His Cyclotide research integrates issues from Cystine Knot Motifs, Protein engineering, Plant protein and Botany. His Nuclear magnetic resonance spectroscopy study combines topics in areas such as Crystallography and Protein secondary structure.
David J. Craik mainly investigates Peptide, Biochemistry, Cyclic peptide, Cyclotides and Cyclotide. His Peptide research includes elements of Sodium channel, Biophysics, Membrane, Stereochemistry and Pharmacology. His study in Amino acid, Peptide sequence, Receptor, Proteases and Enzyme is carried out as part of his Biochemistry studies.
The various areas that he examines in his Cyclic peptide study include Serine protease, Structure–activity relationship, Trypsin, Epitope and Peptidomimetic. David J. Craik has included themes like Violaceae, Botany, Combinatorial chemistry, Cystine knot and Drug in his Cyclotides study. His Cyclotide study incorporates themes from Endopeptidase and Cysteine.
His primary scientific interests are in Peptide, Biochemistry, Cyclic peptide, Cyclotides and Cyclotide. His Peptide research incorporates themes from Biophysics, Lipid bilayer, Stereochemistry and Binding site. Many of his studies on Biochemistry apply to Cancer cell as well.
His Cyclic peptide study integrates concerns from other disciplines, such as Epitope, In vivo, Pharmacology and Trypsin. His Cyclotides research is multidisciplinary, incorporating perspectives in Amino acid, Botany, Combinatorial chemistry, Cystine knot and Drug. His Cyclotide research includes themes of Endopeptidase, Protein engineering, Cysteine, Enzyme and Bovine serum albumin.
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The Future of Peptide‐based Drugs
David J. Craik;David P. Fairlie;Spiros Liras;David Price.
Chemical Biology & Drug Design (2013)
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers.
Natural Product Reports (2013)
Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif
David J Craik;Norelle L Daly;Trudy Bond;Clement Waine.
Journal of Molecular Biology (1999)
A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides.
Paul K. Pallaghy;Katherine J. Nielsen;David J. Craik;Raymond S. Norton.
Protein Science (1994)
Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
Murray Coles;Wendy Bicknell;Andrew A. Watson;David P. Fairlie.
The cystine knot motif in toxins and implications for drug design.
David J. Craik;Norelle L. Daly;Clement Waine.
Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.
Michelle L Colgrave;David J Craik.
Functional-Group Contributions to Drug Receptor Interactions
P. R. Andrews;D. J. Craik;J. L. Martin.
Journal of Medicinal Chemistry (1984)
Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis
Cameron Jennings;Jenny West;Clement Waine;David Craik.
Proceedings of the National Academy of Sciences of the United States of America (2001)
ELUCIDATION OF THE PRIMARY AND THREE-DIMENSIONAL STRUCTURE OF THE UTEROTONIC POLYPEPTIDE KALATA B1
Olav Saether;David J. Craik;Iain D. Campbell;Knut Sletten.
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