D-Index & Metrics Best Publications
Chemistry
Australia
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 114 Citations 43,769 904 World Ranking 354 National Ranking 9
Biology and Biochemistry D-index 119 Citations 46,936 960 World Ranking 445 National Ranking 9

Research.com Recognitions

Awards & Achievements

2023 - Research.com Chemistry in Australia Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

His scientific interests lie mostly in Cyclotide, Cyclotides, Biochemistry, Cystine knot and Stereochemistry. His Cyclotide study introduces a deeper knowledge of Peptide. The study incorporates disciplines such as Drug, Scaffold, Helix, Nicotinic acetylcholine receptor and In vivo in addition to Peptide.

The Cyclotides study combines topics in areas such as Combinatorial chemistry, Violaceae, Botany and Biological activity. David J. Craik has researched Cystine knot in several fields, including Plant protein, Protein folding, Structural motif, Beta sheet and Computational biology. His biological study spans a wide range of topics, including Peptide bond, Conotoxin and Native chemical ligation, Cysteine.

His most cited work include:

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (1048 citations)
  • The Future of Peptide‐based Drugs (966 citations)
  • Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. (583 citations)

What are the main themes of his work throughout his whole career to date?

David J. Craik focuses on Biochemistry, Peptide, Stereochemistry, Cyclotides and Cyclotide. His Peptide research is multidisciplinary, relying on both Protein structure, Biophysics and Membrane. His research in Stereochemistry intersects with topics in Conotoxin, Molecule and Cysteine.

His study in Cyclotides is interdisciplinary in nature, drawing from both Violaceae, Structural motif, Combinatorial chemistry, Cystine knot and Computational biology. His Cyclotide research integrates issues from Cystine Knot Motifs, Protein engineering, Plant protein and Botany. His Nuclear magnetic resonance spectroscopy study combines topics in areas such as Crystallography and Protein secondary structure.

He most often published in these fields:

  • Biochemistry (33.27%)
  • Peptide (30.45%)
  • Stereochemistry (25.58%)

What were the highlights of his more recent work (between 2015-2021)?

  • Peptide (30.45%)
  • Biochemistry (33.27%)
  • Cyclic peptide (16.54%)

In recent papers he was focusing on the following fields of study:

David J. Craik mainly investigates Peptide, Biochemistry, Cyclic peptide, Cyclotides and Cyclotide. His Peptide research includes elements of Sodium channel, Biophysics, Membrane, Stereochemistry and Pharmacology. His study in Amino acid, Peptide sequence, Receptor, Proteases and Enzyme is carried out as part of his Biochemistry studies.

The various areas that he examines in his Cyclic peptide study include Serine protease, Structure–activity relationship, Trypsin, Epitope and Peptidomimetic. David J. Craik has included themes like Violaceae, Botany, Combinatorial chemistry, Cystine knot and Drug in his Cyclotides study. His Cyclotide study incorporates themes from Endopeptidase and Cysteine.

Between 2015 and 2021, his most popular works were:

  • Accurate de novo design of hyperstable constrained peptides. (170 citations)
  • Designing macrocyclic disulfide-rich peptides for biotechnological applications. (66 citations)
  • Cyclotides as drug design scaffolds. (55 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

His primary scientific interests are in Peptide, Biochemistry, Cyclic peptide, Cyclotides and Cyclotide. His Peptide research incorporates themes from Biophysics, Lipid bilayer, Stereochemistry and Binding site. Many of his studies on Biochemistry apply to Cancer cell as well.

His Cyclic peptide study integrates concerns from other disciplines, such as Epitope, In vivo, Pharmacology and Trypsin. His Cyclotides research is multidisciplinary, incorporating perspectives in Amino acid, Botany, Combinatorial chemistry, Cystine knot and Drug. His Cyclotide research includes themes of Endopeptidase, Protein engineering, Cysteine, Enzyme and Bovine serum albumin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Future of Peptide‐based Drugs

David J. Craik;David P. Fairlie;Spiros Liras;David Price.
Chemical Biology & Drug Design (2013)

1677 Citations

Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers.
Natural Product Reports (2013)

1636 Citations

Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif

David J Craik;Norelle L Daly;Trudy Bond;Clement Waine.
Journal of Molecular Biology (1999)

863 Citations

A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides.

Paul K. Pallaghy;Katherine J. Nielsen;David J. Craik;Raymond S. Norton.
Protein Science (1994)

622 Citations

Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

Murray Coles;Wendy Bicknell;Andrew A. Watson;David P. Fairlie.
Biochemistry (1998)

620 Citations

The cystine knot motif in toxins and implications for drug design.

David J. Craik;Norelle L. Daly;Clement Waine.
Toxicon (2001)

601 Citations

Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

Michelle L Colgrave;David J Craik.
Biochemistry (2004)

580 Citations

Functional-Group Contributions to Drug Receptor Interactions

P. R. Andrews;D. J. Craik;J. L. Martin.
Journal of Medicinal Chemistry (1984)

578 Citations

Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis

Cameron Jennings;Jenny West;Clement Waine;David Craik.
Proceedings of the National Academy of Sciences of the United States of America (2001)

553 Citations

ELUCIDATION OF THE PRIMARY AND THREE-DIMENSIONAL STRUCTURE OF THE UTEROTONIC POLYPEPTIDE KALATA B1

Olav Saether;David J. Craik;Iain D. Campbell;Knut Sletten.
Biochemistry (1995)

502 Citations

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