His main research concerns Biochemistry, Mucosal associated invariant T cell, Peptide, Antigen and Immunology. Proteases, Protease, In vitro, Enzyme and Receptor are subfields of Biochemistry in which his conducts study. His Peptide study integrates concerns from other disciplines, such as Protein structure, Helix and Stereochemistry.
His Stereochemistry study combines topics from a wide range of disciplines, such as Cyclic peptide, Amyloid beta and Protein secondary structure. He has researched Antigen in several fields, including T cell and Immune system. His research integrates issues of Cancer research, Pharmacology and Ischemia in his study of Immunology.
His primary areas of study are Stereochemistry, Biochemistry, Peptide, Receptor and Pharmacology. His studies in Stereochemistry integrate themes in fields like Cyclic peptide, Peptidomimetic and Amide. His work is connected to Protease, Enzyme, Proteases, Small molecule and Histone deacetylase, as a part of Biochemistry.
His Peptide study combines topics in areas such as Amino acid, Crystallography, Alpha helix, Helix and Turn. His Receptor study frequently intersects with other fields, such as C5a receptor. The study incorporates disciplines such as Antagonist and Immunology in addition to Pharmacology.
David P. Fairlie focuses on Cell biology, Mucosal associated invariant T cell, Immunology, Antigen and Biochemistry. Proteases, Kidney and Endocrinology is closely connected to Protease-activated receptor 2 in his research, which is encompassed under the umbrella topic of Cell biology. His Mucosal associated invariant T cell research focuses on subjects like Cell activation, which are linked to Interleukin 23.
His study looks at the relationship between Antigen and fields such as T cell, as well as how they intersect with chemical problems. His Biochemistry and Agonist, Peptide, Amino acid, Receptor and Virtual screening investigations all form part of his Biochemistry research activities. His Peptide study incorporates themes from Alpha helix, Plasma protein binding and Stereochemistry.
David P. Fairlie mostly deals with Mucosal associated invariant T cell, Antigen, Immunology, Cell biology and T cell. His Mucosal associated invariant T cell research incorporates themes from Cell activation, Cell, Interleukin 17, Interferon gamma and Interleukin 12. The Antigen study combines topics in areas such as Receptor, Biochemistry and T-cell receptor.
His studies deal with areas such as Histone deacetylase, Histone and In vivo as well as Immunology. His Cell biology research includes themes of Minor histocompatibility antigen, Antigen processing, Antigen presentation and Jurkat cells. His work in T cell covers topics such as Molecular biology which are related to areas like Pulmonary fibrosis, Western blot and CD8.
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The Future of Peptide‐based Drugs
David J. Craik;David P. Fairlie;Spiros Liras;David Price.
Chemical Biology & Drug Design (2013)
Protease inhibitors: current status and future prospects.
Donmienne Leung;Giovanni Abbenante;David P. Fairlie.
Journal of Medicinal Chemistry (2000)
Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity CORRELATION WITH CELL-FREE HYDROGEN PEROXIDE PRODUCTION AND METAL REDUCTION
Xudong Huang;Math P. Cuajungco;Craig S. Atwood;Mariana A. Hartshorn.
Journal of Biological Chemistry (1999)
MR1 presents microbial vitamin B metabolites to MAIT cells
Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours.
Nature (2012)
Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42.
Craig S. Atwood;Richard C. Scarpa;Xudong Huang;Robert D. Moir.
Journal of Neurochemistry (2008)
Aqueous Dissolution of Alzheimer's Disease Aβ Amyloid Deposits by Biometal Depletion *
Robert A. Cherny;Robert A. Cherny;Jacinta T. Legg;Jacinta T. Legg;Catriona A. McLean;Catriona A. McLean;David P. Fairlie.
Journal of Biological Chemistry (1999)
Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
Murray Coles;Wendy Bicknell;Andrew A. Watson;David P. Fairlie.
Biochemistry (1998)
T-cell activation by transitory neo-antigens derived from distinct microbial pathways
Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu.
Nature (2014)
Proteases universally recognize beta strands in their active sites.
Joel D. A. Tyndall;Tessa Nall;David P. Fairlie.
Chemical Reviews (2005)
Histone deacetylases as regulators of inflammation and immunity.
Melanie R. Shakespear;Maria A. Halili;Katharine M. Irvine;David P. Fairlie.
Trends in Immunology (2011)
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