D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 89 Citations 29,693 346 World Ranking 1132 National Ranking 26

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

His main research concerns Biochemistry, Mucosal associated invariant T cell, Peptide, Antigen and Immunology. Proteases, Protease, In vitro, Enzyme and Receptor are subfields of Biochemistry in which his conducts study. His Peptide study integrates concerns from other disciplines, such as Protein structure, Helix and Stereochemistry.

His Stereochemistry study combines topics from a wide range of disciplines, such as Cyclic peptide, Amyloid beta and Protein secondary structure. He has researched Antigen in several fields, including T cell and Immune system. His research integrates issues of Cancer research, Pharmacology and Ischemia in his study of Immunology.

His most cited work include:

  • The Future of Peptide‐based Drugs (966 citations)
  • MR1 presents microbial vitamin B metabolites to MAIT cells (790 citations)
  • Protease inhibitors: current status and future prospects. (671 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Stereochemistry, Biochemistry, Peptide, Receptor and Pharmacology. His studies in Stereochemistry integrate themes in fields like Cyclic peptide, Peptidomimetic and Amide. His work is connected to Protease, Enzyme, Proteases, Small molecule and Histone deacetylase, as a part of Biochemistry.

His Peptide study combines topics in areas such as Amino acid, Crystallography, Alpha helix, Helix and Turn. His Receptor study frequently intersects with other fields, such as C5a receptor. The study incorporates disciplines such as Antagonist and Immunology in addition to Pharmacology.

He most often published in these fields:

  • Stereochemistry (23.68%)
  • Biochemistry (22.85%)
  • Peptide (15.40%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cell biology (9.77%)
  • Mucosal associated invariant T cell (6.79%)
  • Immunology (10.93%)

In recent papers he was focusing on the following fields of study:

David P. Fairlie focuses on Cell biology, Mucosal associated invariant T cell, Immunology, Antigen and Biochemistry. Proteases, Kidney and Endocrinology is closely connected to Protease-activated receptor 2 in his research, which is encompassed under the umbrella topic of Cell biology. His Mucosal associated invariant T cell research focuses on subjects like Cell activation, which are linked to Interleukin 23.

His study looks at the relationship between Antigen and fields such as T cell, as well as how they intersect with chemical problems. His Biochemistry and Agonist, Peptide, Amino acid, Receptor and Virtual screening investigations all form part of his Biochemistry research activities. His Peptide study incorporates themes from Alpha helix, Plasma protein binding and Stereochemistry.

Between 2014 and 2021, his most popular works were:

  • Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant t cells using MR1 tetramers (201 citations)
  • A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage (169 citations)
  • Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation. (151 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

David P. Fairlie mostly deals with Mucosal associated invariant T cell, Antigen, Immunology, Cell biology and T cell. His Mucosal associated invariant T cell research incorporates themes from Cell activation, Cell, Interleukin 17, Interferon gamma and Interleukin 12. The Antigen study combines topics in areas such as Receptor, Biochemistry and T-cell receptor.

His studies deal with areas such as Histone deacetylase, Histone and In vivo as well as Immunology. His Cell biology research includes themes of Minor histocompatibility antigen, Antigen processing, Antigen presentation and Jurkat cells. His work in T cell covers topics such as Molecular biology which are related to areas like Pulmonary fibrosis, Western blot and CD8.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Future of Peptide‐based Drugs

David J. Craik;David P. Fairlie;Spiros Liras;David Price.
Chemical Biology & Drug Design (2013)

1435 Citations

Protease inhibitors: current status and future prospects.

Donmienne Leung;Giovanni Abbenante;David P. Fairlie.
Journal of Medicinal Chemistry (2000)

1150 Citations

Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity CORRELATION WITH CELL-FREE HYDROGEN PEROXIDE PRODUCTION AND METAL REDUCTION

Xudong Huang;Math P. Cuajungco;Craig S. Atwood;Mariana A. Hartshorn.
Journal of Biological Chemistry (1999)

955 Citations

MR1 presents microbial vitamin B metabolites to MAIT cells

Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours.
Nature (2012)

807 Citations

Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42.

Craig S. Atwood;Richard C. Scarpa;Xudong Huang;Robert D. Moir.
Journal of Neurochemistry (2008)

746 Citations

Aqueous Dissolution of Alzheimer's Disease Aβ Amyloid Deposits by Biometal Depletion *

Robert A. Cherny;Robert A. Cherny;Jacinta T. Legg;Jacinta T. Legg;Catriona A. McLean;Catriona A. McLean;David P. Fairlie.
Journal of Biological Chemistry (1999)

629 Citations

Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

Murray Coles;Wendy Bicknell;Andrew A. Watson;David P. Fairlie.
Biochemistry (1998)

594 Citations

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu.
Nature (2014)

502 Citations

Proteases universally recognize beta strands in their active sites.

Joel D. A. Tyndall;Tessa Nall;David P. Fairlie.
Chemical Reviews (2005)

422 Citations

Histone deacetylases as regulators of inflammation and immunity.

Melanie R. Shakespear;Maria A. Halili;Katharine M. Irvine;David P. Fairlie.
Trends in Immunology (2011)

418 Citations

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