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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
108
Citations
44084
World Ranking
1042
National Ranking
28

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

David P. Fairlie is affiliated with the University of Queensland in Australia and has contributed extensively to research in immunology, molecular biology, and medicine. Their published work spans several interdisciplinary fields, with a strong focus on immune cell function and interaction as well as molecular pathways involved in immune responses.

Their main fields of study include:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, Fairlie's subfields of study involve:

  • Immunology
  • Molecular Biology
  • Epidemiology
  • Cell Biology
  • Hematology

Key topics in their research encompass:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Chemical Synthesis and Analysis
  • Histone Deacetylase Inhibitors Research
  • Cytomegalovirus and herpesvirus research
  • Phagocytosis and Immune Regulation
  • Immunotherapy and Immune Responses

David P. Fairlie has co-authored publications with several frequent collaborators, including:

  • Jeffrey Y. W. Mak
  • James McCluskey
  • Ligong Liu
  • Jamie Rossjohn
  • Junxian Lim

Their work has been published in several prominent venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • IUPHAR/BPS Guide to Pharmacology CITE
  • Proceedings of the National Academy of Sciences
  • Journal of Medicinal Chemistry
  • Journal of Biological Chemistry

Recent notable papers by David P. Fairlie include:

  • "Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc," published in 2021 in Molecular Cancer
  • "Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches," published in 2020 in Advanced Drug Delivery Reviews
  • "MAIT cells regulate NK cell-mediated tumor immunity," published in 2021 in Nature Communications
  • "Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2," published in 2020 in Cell Reports
  • "Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1," published in 2020 in Science Immunology

Best Publications

  • The Future of Peptide‐based Drugs

    David J. Craik;David P. Fairlie;Spiros Liras;David Price

  • MR1 presents microbial vitamin B metabolites to MAIT cells

    Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours

  • Protease inhibitors: current status and future prospects.

    Donmienne Leung;Giovanni Abbenante;David P. Fairlie

  • Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity CORRELATION WITH CELL-FREE HYDROGEN PEROXIDE PRODUCTION AND METAL REDUCTION

    Xudong Huang;Math P. Cuajungco;Craig S. Atwood;Mariana A. Hartshorn

  • T-cell activation by transitory neo-antigens derived from distinct microbial pathways

    Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu

  • Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42.

    Craig S. Atwood;Richard C. Scarpa;Xudong Huang;Robert D. Moir

  • Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

    Murray Coles;Wendy Bicknell;Andrew A. Watson;David P. Fairlie

  • Aqueous Dissolution of Alzheimer's Disease Aβ Amyloid Deposits by Biometal Depletion *

    Robert A. Cherny;Robert A. Cherny;Jacinta T. Legg;Jacinta T. Legg;Catriona A. McLean;Catriona A. McLean;David P. Fairlie

  • Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

    Rangsima Reantragoon;Alexandra Corbett;Isaac G Sakala;Nicholas A Gherardin;Nicholas A Gherardin

  • Histone deacetylases as regulators of inflammation and immunity.

    Melanie R. Shakespear;Maria A. Halili;Katharine M. Irvine;David P. Fairlie

  • Function, structure and therapeutic potential of complement C5a receptors

    Monk Pn;Scola Am;Madala P;Fairlie Dp

  • Proteases universally recognize beta strands in their active sites.

    Joel D. A. Tyndall;Tessa Nall;David P. Fairlie

  • Structure, function and pathophysiology of protease activated receptors.

    Mark N. Adams;Rithwik Ramachandran;Mei Kwan Yau;Jacky Y. Suen

  • Activity of Recombinant Dengue 2 Virus NS3 Protease in the Presence of a Truncated NS2B Co-factor, Small Peptide Substrates, and Inhibitors

    Donmienne Leung;Kate Schroder;Helen White;Ning-Xia Fang

  • Constraining Cyclic Peptides To Mimic Protein Structure Motifs

    Timothy A. Hill;Nicholas E. Shepherd;Frederik Diness;David P. Fairlie

  • Protease inhibitors in the clinic.

    Giovanni Abbenante;David P Fairlie

  • Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles

    Richard M. Meade;David P. Fairlie;Jody M. Mason;Jody M. Mason

  • Orally Absorbed Cyclic Peptides

    Daniel S. Nielsen;Nicholas E. Shepherd;Weijun Xu;Andrew J. Lucke

  • Single turn peptide alpha helices with exceptional stability in water.

    Nicholas E Shepherd;Huy N Hoang;Giovanni Abbenante;David P Fairlie

  • Inflammatory lipid mediators in adipocyte function and obesity

    Abishek Iyer;David P. Fairlie;Johannes B. Prins;Bruce D. Hammock

Frequent Co-Authors

Jamie Rossjohn
Jamie Rossjohn Monash University
James McCluskey
James McCluskey University of Melbourne
Paul R. Young
Paul R. Young University of Queensland
Zhenjun Chen
Zhenjun Chen University of Melbourne
Dale I. Godfrey
Dale I. Godfrey University of Melbourne
Graeme R. Hanson
Graeme R. Hanson University of Queensland
Jennifer L. Martin
Jennifer L. Martin University of Wollongong
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne
Katherine Thea Andrews
Katherine Thea Andrews Griffith University
Matthew J. Sweet
Matthew J. Sweet University of Queensland

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