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2025
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Neuroscience
Australia
2026

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Best Scientists

D-Index
175
Citations
129343
World Ranking
713
National Ranking
17

Neuroscience

D-Index
177
Citations
135818
World Ranking
60
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Australia Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Neuroscience in Australia Leader Award
  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award
  • 2023 - Research.com Medicine in Australia Leader Award
  • 2022 - Research.com Biology and Biochemistry in Australia Leader Award
  • 2015 - Fellow of the Australian Academy of Health and Medical Science

Overview

Colin L. Masters is affiliated with the University of Melbourne in Australia. Their research primarily focuses on medicine, with significant contributions to physiology, psychiatry and mental health, molecular biology, neurology, and cognitive neuroscience.

The scientist's work centers on several key topics: Alzheimer's disease research and treatments, dementia and cognitive impairment research, functional brain connectivity studies, advanced neuroimaging techniques and applications, health, environment, cognitive aging, neuroinflammation and neurodegeneration mechanisms, and prion diseases and protein misfolding.

Recent notable publications include:

  • The Amyloid-β Pathway in Alzheimer's Disease (2021, Molecular Psychiatry)
  • A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease (2020, Nature Medicine)
  • Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline (2022, Nature Medicine)
  • MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14,468 individuals worldwide (2020, Brain)
  • A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease (2021, Nature Medicine)

Frequent co-authors in their research collaborations include:

  • Ralph N. Martins (105 joint publications)
  • Christopher C. Rowe (104 joint publications)
  • Victor L. Villemagne (96 joint publications)
  • Christopher Fowler (84 joint publications)
  • Paul Maruff (78 joint publications)

The scientist has published extensively in several venues, with the highest number of works found in Alzheimer s & Dementia, followed by bioRxiv (Cold Spring Harbor Laboratory), Journal of Alzheimer s Disease, Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring, and Nature Communications.

Awards include being named a Fellow of the Australian Academy of Health and Medical Science in 2015.

Best Publications

  • Amyloid plaque core protein in Alzheimer disease and Down syndrome

    Colin L. Masters;Gail Simms;Nicola A. Weinman;Gerd Multhaup

  • Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

    Randall J. Bateman;Chengjie Xiong;Tammie L.S. Benzinger;Anne M. Fagan

  • Neurodegenerative diseases and oxidative stress.

    Kevin J. Barnham;Colin L. Masters;Ashley I. Bush;Ashley I. Bush

  • Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.

    Catriona A. McLean;Robert A. Cherny;Fiona W. Fraser;Stephanie J. Fuller

  • Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.

    Victor L. Villemagne;Samantha Burnham;Pierrick Bourgeat;Belinda M. Brown

  • Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

    Robert A Cherny;Craig S Atwood;Michel E Xilinas;Danielle N Gray

  • High performance plasma amyloid-β biomarkers for Alzheimer’s disease

    Akinori Nakamura;Naoki Kaneko;Victor L Villemagne;Takashi Kato

  • The Amyloid-β Pathway in Alzheimer's Disease.

    Harald Hampel;John Hardy;Kaj Blennow;Kaj Blennow;Christopher Chen

  • Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

    C L Masters;G Multhaup;G Simms;J Pottgiesser

  • Imaging beta-amyloid burden in aging and dementia.

    Christopher C Rowe;Steven Ng;Uwe Ackermann;Sylvia Gong

  • Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial

    Craig W Ritchie;Ashley I Bush;Andrew J Mackinnon;Steve Macfarlane

  • The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: Methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease

    Kathryn A Ellis;Ashley I Bush;David Darby;Daniela De Fazio

  • Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging

    Christopher C Rowe;Kathryn A Ellis;Kathryn A Ellis;Miroslava Rimajova;Pierrick Bourgeat

  • Longitudinal Assessment of Aβ and Cognition in Aging and Alzheimer Disease

    Victor L Villemagne;Kerryn E Pike;Gaël Chételat;Kathryn A Ellis

  • The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I)

    Gerd Multhaup;Andrea Schlicksupp;Lars Hesse;Dirk Beher

  • Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

    Tobias Hartmann;Sophie C. Bieger;Babara Brühl;Pentti J. Tienari

  • Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.

    Kerryn Elizabeth Pike;Gregory Raymond Savage;Victor L Villemagne;Steven Ng

  • Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

    Oliver Preische;Oliver Preische;Stephanie A. Schultz;Anja Apel;Anja Apel;Jens Kuhle

  • Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

    Lars Lannfelt;Kaj Blennow;Henrik Zetterberg;Stellan Batsman

  • Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits

    Cyril C. Curtain;Feda Ali;Irene Volitakis;Robert A. Cherny

  • Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

    Baden Rumble;Robert Retallack;Caroline Hilbich;Gail Simms

  • Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

    James A. Duce;Andrew Tsatsanis;Michael A. Cater;Simon A. James

Frequent Co-Authors

Christopher C. Rowe
Christopher C. Rowe University of Melbourne
Victor L. Villemagne
Victor L. Villemagne University of Pittsburgh
Ralph N. Martins
Ralph N. Martins Edith Cowan University
David Ames
David Ames University of Melbourne
Konrad Beyreuther
Konrad Beyreuther Heidelberg University
Ashley I. Bush
Ashley I. Bush Florey Institute of Neuroscience and Mental Health
Kathryn A. Ellis
Kathryn A. Ellis University of Melbourne
Roberto Cappai
Roberto Cappai University of Melbourne
Kevin J. Barnham
Kevin J. Barnham Florey Institute of Neuroscience and Mental Health
Cassandra Szoeke
Cassandra Szoeke University of Melbourne

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