World's Best Scientists 2026 revealed!
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Best Female Scientists
2025
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Neuroscience
USA
2026

D-Index & Metrics

Best Female Scientists

D-Index
144
Citations
97604
World Ranking
186
National Ranking
114

Neuroscience

D-Index
145
Citations
107946
World Ranking
166
National Ranking
105

Medicine

D-Index
145
Citations
108043
World Ranking
1358
National Ranking
791

Research.com Recognitions

  • 2026 - Research.com Neuroscience in United States Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Neuroscience in United States Leader Award
  • 2015 - Sedgwick Memorial Medal, American Public Health Association
  • 2015 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology

Overview

Reisa A. Sperling is affiliated with Brigham and Women's Hospital in the United States and has an extensive research portfolio primarily focused on dementia, cognitive impairment, and Alzheimer's disease. Their scholarly contributions span multiple significant topics, including dementia and cognitive impairment research, Alzheimer's disease research and treatments, functional brain connectivity studies, advanced neuroimaging techniques and applications, health systems and economic evaluations with quality of life considerations, health, environment, cognitive aging, and cancer-related cognitive impairment studies.

Their work is most frequently published in notable venues such as Alzheimer's & Dementia, The Journal of Prevention of Alzheimer's Disease, JAMA Neurology, Alzheimer's Research & Therapy, and bioRxiv (Cold Spring Harbor Laboratory). These platforms reflect their active engagement in the field of medicine and related subfields.

Reisa A. Sperling's main fields and subfields of study include:

  • Medicine
  • Psychiatry and Mental Health
  • Physiology
  • Cognitive Neuroscience
  • Radiology, Nuclear Medicine and Imaging
  • Neurology

Their recent significant publications include the following:

  • "Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup" (2024), Alzheimer's & Dementia
  • "The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease" (2022), Alzheimer's & Dementia
  • "Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline" (2022), Nature Medicine
  • "Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals" (2020), JAMA Neurology
  • "Trial of Solanezumab in Preclinical Alzheimer's Disease" (2023), New England Journal of Medicine

Frequent collaborators in their research include Keith A. Johnson, Dorene M. Rentz, Rachel F. Buckley, Aaron P. Schultz, and Michael J Properzi.

Awards recognizing their contributions include the Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases from the American Academy of Neurology in 2015, and the Sedgwick Memorial Medal from the American Public Health Association in the same year.

Best Publications

  • NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

    Clifford R. Jack;David A. Bennett;Kaj Blennow;Maria C. Carrillo

  • Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

    Reisa A. Sperling;Paul S. Aisen;Laurel A. Beckett;David A. Bennett

  • Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

    Randall J. Bateman;Chengjie Xiong;Tammie L.S. Benzinger;Anne M. Fagan

  • Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease

    Randy L. Buckner;Jorge Sepulcre;Tanveer Talukdar;Fenna M. Krienen

  • A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease

    Frank Jessen;Frank Jessen;Rebecca E. Amariglio;Martin van Boxtel;Monique Breteler

  • Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

    Clifford R. Jack;Marilyn S. Albert;David S. Knopman;Guy M. McKhann

  • Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

    Stephen Salloway;Reisa Sperling;Nick C. Fox;Kaj Blennow

  • Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria.

    Bruno Dubois;Harald Hampel;Harald Hampel;Howard H. Feldman;Philip Scheltens

  • Defeating Alzheimer's disease and other dementias: a priority for European science and society

    Bengt Winblad;Bengt Winblad;Philippe Amouyel;Sandrine Andrieu;Clive Ballard

  • A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

    Clifford R. Jack;David A. Bennett;Kaj Blennow;Maria C. Carrillo

  • Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

    Peter T. Nelson;Dennis W. Dickson;John Q. Trojanowski;Clifford R. Jack

  • The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals

    Bradford C. Dickerson;Akram Bakkour;David H. Salat;Eric Feczko

  • Tau positron emission tomographic imaging in aging and early Alzheimer disease

    Keith A. Johnson;Aaron Schultz;Rebecca A. Betensky;J. Alex Becker

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • Amyloid deposition is associated with impaired default network function in older persons without dementia

    Reisa A. Sperling;Reisa A. Sperling;Peter S. LaViolette;Kelly O'Keefe;Jacqueline O'Brien

  • Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD

    B. C. Dickerson;D. H. Salat;D. N. Greve;E. F. Chua

  • Alterations in Memory Networks in Mild Cognitive Impairment and Alzheimer's Disease: An Independent Component Analysis

    Kim A. Celone;Vince D. Calhoun;Bradford C. Dickerson;Alireza Atri

  • A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease.

    S. Salloway;R. Sperling;S. Gilman;N.C.I. Fox

  • Brain Imaging in Alzheimer Disease

    Keith A. Johnson;Nick C. Fox;Reisa A. Sperling;William E. Klunk

  • Cerebral amyloid angiopathy and Alzheimer disease — one peptide, two pathways

    Steven M. Greenberg;Brian J. Bacskai;Mar Hernandez-Guillamon;Jeremy Pruzin

  • The A4 Study: Stopping AD Before Symptoms Begin?

    Reisa A. Sperling;Dorene M. Rentz;Dorene M. Rentz;Keith A. Johnson;Keith A. Johnson;Jason Karlawish

Frequent Co-Authors

Keith A. Johnson
Keith A. Johnson Harvard University
Dorene M. Rentz
Dorene M. Rentz Harvard Medical School
Rebecca Amariglio
Rebecca Amariglio Harvard Medical School
Aaron P. Schultz
Aaron P. Schultz Harvard University
Gad A. Marshall
Gad A. Marshall Brigham and Women's Hospital
Jasmeer P. Chhatwal
Jasmeer P. Chhatwal Harvard University
Kathryn V. Papp
Kathryn V. Papp Harvard University
Paul S. Aisen
Paul S. Aisen University of Southern California
Stephen Salloway
Stephen Salloway Brown University
Elizabeth C. Mormino
Elizabeth C. Mormino Stanford University

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