World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Medicine
USA
2026

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Best Scientists

D-Index
207
Citations
179797
World Ranking
225
National Ranking
148

Neuroscience

D-Index
217
Citations
194304
World Ranking
16
National Ranking
10

Medicine

D-Index
218
Citations
197602
World Ranking
96
National Ranking
70

Research.com Recognitions

  • 2026 - Research.com Medicine in United States Leader Award
  • 2026 - Research.com Neuroscience in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in United States Leader Award
  • 2025 - Research.com Neuroscience in United States Leader Award
  • 2018 - Sedgwick Memorial Medal, American Public Health Association
  • 2018 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

David A. Bennett is affiliated with Rush University Medical Center in the United States. The main fields of study connected to their work include Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans several subfields such as Molecular Biology, Physiology, Psychiatry and Mental Health, Neurology, and Genetics.

The scientist's research focuses primarily on topics related to Alzheimer's disease, including research and treatments. Other key topics in their work cover Dementia and Cognitive Impairment Research, Neuroinflammation and Neurodegeneration Mechanisms, Bioinformatics and Genomic Networks, Epigenetics and DNA Methylation, Genetic Associations and Epidemiology, and Health Disparities and Outcomes.

Among their recent publications are:

  • Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease, 2020, Nature Medicine
  • Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation, 2020, Nature Medicine
  • Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease, 2020, Nature Communications
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level, 2022, Nature Neuroscience
  • APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes, 2022, Nature

The scientist collaborates frequently with other researchers. Notable coauthors include:

  • Julie A. Schneider
  • Philip L. De Jager
  • Lisa L. Barnes
  • Aron S. Buchman
  • Lei Yu

Their work has been published extensively in several venues, with the most frequent being:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Journal of Alzheimer's Disease
  • Nature Communications

David A. Bennett has received recognition in the form of awards such as the Sedgwick Memorial Medal from the American Public Health Association in 2018, the Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases awarded by the American Academy of Neurology in 2018, and has been named a Fellow of The Academy of Medical Sciences in the United Kingdom.

Best Publications

  • NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

    Clifford R. Jack;David A. Bennett;Kaj Blennow;Maria C. Carrillo

  • Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

    Reisa A. Sperling;Paul S. Aisen;Laurel A. Beckett;David A. Bennett

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Mild cognitive impairment

    Serge Gauthier;Barry Reisberg;Michael Zaudig;Ronald C. Petersen

  • Single-cell transcriptomic analysis of Alzheimer’s disease

    Hansruedi Mathys;Hansruedi Mathys;Jose Davila-Velderrain;Jose Davila-Velderrain;Zhuyu Peng;Zhuyu Peng;Fan Gao;Fan Gao

  • Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment

    Ronald C. Petersen;Ronald G. Thomas;Michael Grundman;David Bennett

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • MIXED BRAIN PATHOLOGIES ACCOUNT FOR MOST DEMENTIA CASES IN COMMUNITY-DWELLING OLDER PERSONS

    Julie A. Schneider;Zoe Arvanitakis;Woojeong Bang;David A. Bennett

  • Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

    Konrad Talbot;Hoau-Yan Wang;Hala Kazi;Li-Ying Han

  • Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

    Bin Zhang;Chris Gaiteri;Liviu Gabriel Bodea;Zhi Wang

  • A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

    Clifford R. Jack;David A. Bennett;Kaj Blennow;Maria C. Carrillo

  • Participation in Cognitively Stimulating Activities and Risk of Incident Alzheimer Disease

    Robert S. Wilson;Carlos F. Mendes de Leon;Lisa L. Barnes;Julie A. Schneider

  • Loneliness and Risk of Alzheimer Disease

    Robert S. Wilson;Kristin R. Krueger;Steven E. Arnold;Julie A. Schneider

  • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function.

    Zoe Arvanitakis;Robert S. Wilson;Julia L. Bienias;Denis A. Evans

  • Consumption of Fish and n-3 Fatty Acids and Risk of Incident Alzheimer Disease

    Marthac Clare Morris;Denis A. Evans;Julia L. Bienias;Christine C. Tangney

  • Charting a dynamic DNA methylation landscape of the human genome

    Michael J. Ziller;Hongcang Gu;Fabian Müller;Julie Donaghey;Julie Donaghey

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • Neuropathology of older persons without cognitive impairment from two community-based studies

    D. A. Bennett;J. A. Schneider;Z. Arvanitakis;J. F. Kelly

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Natural history of mild cognitive impairment in older persons.

    D. A. Bennett;R. S. Wilson;J. A. Schneider;D. A. Evans

Frequent Co-Authors

Philip L. De Jager
Philip L. De Jager Columbia University
Julie A. Schneider
Julie A. Schneider Rush University Medical Center
Robert S. Wilson
Robert S. Wilson Rush University Medical Center
Lei Yu
Lei Yu Rush University Medical Center
Aron S. Buchman
Aron S. Buchman Rush University Medical Center
Patricia A. Boyle
Patricia A. Boyle Rush University Medical Center
Sue Leurgans
Sue Leurgans Rush University Medical Center
Konstantinos Arfanakis
Konstantinos Arfanakis Illinois Institute of Technology
Lisa L. Barnes
Lisa L. Barnes Rush University Medical Center
Denis A. Evans
Denis A. Evans Rush University Medical Center

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