2026 Makoto Kuro-o: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Medicine	104	6985	6571	165	157	355	45948

Makoto Kuro-o publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Makoto Kuro-o sits on this spectrum.

101 publications 1,796+

This scientist: 355 publications — 29th percentile

29% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Makoto Kuro-o D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Makoto Kuro-o sits on this spectrum.

70 D-Index 217+

This scientist: 104 D-Index — 66th percentile

66% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Makoto Kuro-o is affiliated with Jichi Medical University in Japan. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, their notable subfields of study include Nephrology, Molecular Biology, Genetics, Physiology, and Surgery.

The scientist's research topics cover a range of biomedical and clinical interests. Key topics include:

Parathyroid Disorders and Treatments
Dialysis and Renal Disease Management
Genetic Syndromes and Imprinting
Fibroblast Growth Factor Research
Magnesium in Health and Disease
Biomedical Research and Pathophysiology
Nutrition and Health in Aging

Makoto Kuro-o has contributed to several peer-reviewed publications. Some selected papers include:

"Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression", 2021, Journal of Clinical Investigation
"Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho", 2021, Molecular Psychiatry
"Klotho and calciprotein particles as therapeutic targets against accelerated ageing", 2021, Clinical Science
"Mud in the blood: the role of protein-mineral complexes and extracellular vesicles in biomineralisation and calcification", 2020, Journal of Structural Biology
"Phosphate as a Pathogen of Arteriosclerosis and Aging", 2020, Journal of Atherosclerosis and Thrombosis

The venues where Makoto Kuro-o frequently publishes reflect their research focus. Notable publication venues include:

Scientific Reports
Experimental Gerontology
Medicine & Science in Sports & Exercise
Hypertension Research
Research Square (Research Square)

Collaboration is a key aspect of their work, with frequent co-authors including:

Keisei Kosaki
Seiji Maeda
Masahiro Matsui
Kunihiro Yamagata
Chie Saito

Best Publications

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Makoto Kuro-o;Yutaka Matsumura;Hiroki Aizawa;Hiroshi Kawaguchi

4204
Citations
FGF23 induces left ventricular hypertrophy

Christian Faul;Ansel P. Amaral;Behzad Oskouei;Ming Chang Hu

2203
Citations
Suppression of Aging in Mice by the Hormone Klotho

Hiroshi Kurosu;Masaya Yamamoto;Jeremy D. Clark;Johanne V. Pastor

2064
Citations
Regulation of Fibroblast Growth Factor-23 Signaling by Klotho

Hiroshi Kurosu;Yasushi Ogawa;Masayoshi Miyoshi;Masaya Yamamoto

1544
Citations
Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease

Ming Chang Hu;Mingjun Shi;Jianning Zhang;Henry Quiñones

1389
Citations
The parathyroid is a target organ for FGF23 in rats

Iddo Z. Ben-Dov;Hillel Galitzer;Vardit Lavi-Moshayoff;Regina Goetz

1144
Citations
Tissue-specific Expression of βKlotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21

Hiroshi Kurosu;Mihwa Choi;Yasushi Ogawa;Addie S. Dickson

834
Citations
Regulation of oxidative stress by the anti-aging hormone klotho

Masaya Yamamoto;Jeremy D. Clark;Johanne V. Pastor;Prem Gurnani

807
Citations
IDENTIFICATION OF THE HUMAN KLOTHO GENE AND ITS TWO TRANSCRIPTS ENCODING MEMBRANE AND SECRETED KLOTHO PROTEIN

Yutaka Matsumura;Hiroki Aizawa;Takako Shiraki-Iida;Ryozo Nagai

795
Citations
Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

Klementina Fon Tacer;Angie L. Bookout;Xunshan Ding;Hiroshi Kurosu

755
Citations
βKlotho is required for metabolic activity of fibroblast growth factor 21

Yasushi Ogawa;Hiroshi Kurosu;Masaya Yamamoto;Animesh Nandi

700
Citations
Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

Ming Chang Hu;Mingjun Shi;Jianning Zhang;Johanne Pastor

669
Citations
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

Regina Goetz;Andrew Beenken;Omar A. Ibrahimi;Juliya Kalinina

656
Citations
Fibroblast Growth Factor 23 and Klotho: Physiology and Pathophysiology of an Endocrine Network of Mineral Metabolism

Ming Chang Hu;Kazuhiro Shiizaki;Makoto Kuro-o;Orson W. Moe

632
Citations
Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

Shigehiro Doi;Yonglong Zou;Osamu Togao;Johanne V. Pastor

623
Citations
The Klotho proteins in health and disease

Makoto Kuro-o;Makoto Kuro-o

582
Citations
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

Seung Kuy Cha;Bernardo Ortega;Hiroshi Kurosu;Kevin P. Rosenblatt

481
Citations
Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective

Ming-Chang Hu;Mingjun Shi;Jianning Zhang;Henry Quiñones

449
Citations
Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

Takako Shiraki-Iida;Hiroki Aizawa;Yutaka Matsumura;Susumu Sekine

422
Citations
Mutation of the mouse klotho gene leads to a syndrome resembling ageing

M. Kuro-o;Y. Matsumura;H. Arawa;H. Kawaguchi

27
Citations

Frequent Co-Authors

Ryozo Nagai Jichi Medical University

Yoshio Yazaki University of Tokyo

Masanori Aikawa Brigham and Women's Hospital

Orson W. Moe The University of Texas Southwestern Medical Center

Yo-ichi Nabeshima Foundation for Biomedical Research

Ichiro Manabe Chiba University

Fumimaro Takaku University of Tokyo

Florian Lang University of Tübingen

Moosa Mohammadi New York University Langone Medical Center

Hiroshi Kawaguchi University of Tokyo

External Links

Personal website of Makoto Kuro-o

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