D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 94 Citations 38,112 320 World Ranking 6328 National Ranking 160

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • DNA

His primary scientific interests are in Klotho, Endocrinology, Internal medicine, Fibroblast growth factor and Biochemistry. His Klotho study combines topics in areas such as Cancer research, Wnt signaling pathway, Extracellular, Cell biology and Exon. Kidney disease, Hormone, Kidney, Arteriosclerosis and Homeostasis are subfields of Endocrinology in which his conducts study.

His Fibroblast growth factor research is multidisciplinary, relying on both Signal transduction and Fibroblast growth factor 23. His Signal transduction study combines topics from a wide range of disciplines, such as Growth factor and Phosphorylation. Makoto Kuro-o has researched Biochemistry in several fields, including Presenilin and Amyloid precursor protein.

His most cited work include:

  • Mutation of the mouse klotho gene leads to a syndrome resembling ageing (2566 citations)
  • FGF23 induces left ventricular hypertrophy (1321 citations)
  • Suppression of Aging in Mice by the Hormone Klotho (1266 citations)

What are the main themes of his work throughout his whole career to date?

Internal medicine, Endocrinology, Klotho, Kidney disease and Cell biology are his primary areas of study. Internal medicine is closely attributed to Cardiology in his work. He interconnects Calcification, Calcium and Phosphate in the investigation of issues within Endocrinology.

Makoto Kuro-o has included themes like Receptor, Fibroblast growth factor, Signal transduction and Transgene in his Klotho study. His work carried out in the field of Kidney disease brings together such families of science as Nephrology, Nephron, Renal function, Urinary system and Biomarker. His Cell biology research includes themes of Gene isoform and Smooth muscle.

He most often published in these fields:

  • Internal medicine (59.40%)
  • Endocrinology (55.22%)
  • Klotho (51.64%)

What were the highlights of his more recent work (between 2017-2021)?

  • Internal medicine (59.40%)
  • Endocrinology (55.22%)
  • Klotho (51.64%)

In recent papers he was focusing on the following fields of study:

His main research concerns Internal medicine, Endocrinology, Klotho, Kidney disease and Kidney. His study in the field of Myocyte also crosses realms of Context. With his scientific publications, his incorporates both Klotho and Premature aging.

His biological study spans a wide range of topics, including Urinary system, Osteoporosis and Nephron, Renal function. In his study, Nucleic acid is strongly linked to Molecular biology, which falls under the umbrella field of Kidney. His FGF21 study also includes

  • Endocrine system, which have a strong connection to Fibroblast growth factor, Metabolic Bone Disorder and Disease,
  • Blood pressure together with Aerobic exercise.

Between 2017 and 2021, his most popular works were:

  • The Klotho proteins in health and disease (123 citations)
  • The Klotho proteins in health and disease (123 citations)
  • Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia. (58 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • DNA

His primary scientific interests are in Klotho, Internal medicine, Fibroblast growth factor 23, Endocrinology and Calcium. His Klotho research includes elements of FGF21, Receptor and Fibroblast growth factor. His work in Internal medicine is not limited to one particular discipline; it also encompasses Cardiology.

His Fibroblast growth factor 23 research includes themes of Cardiac function curve, Contractility, Patch clamp and Diastole. His Endocrinology research integrates issues from Ryanodine receptor and Ca2+/calmodulin-dependent protein kinase. His research in Calcium intersects with topics in Extracellular, Cancer research, Signal transduction and Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Makoto Kuro-o;Yutaka Matsumura;Hiroki Aizawa;Hiroshi Kawaguchi.
Nature (1997)

3705 Citations

FGF23 induces left ventricular hypertrophy

Christian Faul;Ansel P. Amaral;Behzad Oskouei;Ming Chang Hu.
Journal of Clinical Investigation (2011)

1976 Citations

Suppression of Aging in Mice by the Hormone Klotho

Hiroshi Kurosu;Masaya Yamamoto;Jeremy D. Clark;Johanne V. Pastor.
Science (2005)

1803 Citations

Regulation of Fibroblast Growth Factor-23 Signaling by Klotho

Hiroshi Kurosu;Yasushi Ogawa;Masayoshi Miyoshi;Masaya Yamamoto.
Journal of Biological Chemistry (2006)

1447 Citations

Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease

Ming Chang Hu;Mingjun Shi;Jianning Zhang;Henry Quiñones.
Journal of The American Society of Nephrology (2011)

1290 Citations

The parathyroid is a target organ for FGF23 in rats

Iddo Z. Ben-Dov;Hillel Galitzer;Vardit Lavi-Moshayoff;Regina Goetz.
Journal of Clinical Investigation (2007)

1082 Citations

Tissue-specific Expression of βKlotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21

Hiroshi Kurosu;Mihwa Choi;Yasushi Ogawa;Addie S. Dickson.
Journal of Biological Chemistry (2007)

769 Citations

IDENTIFICATION OF THE HUMAN KLOTHO GENE AND ITS TWO TRANSCRIPTS ENCODING MEMBRANE AND SECRETED KLOTHO PROTEIN

Yutaka Matsumura;Hiroki Aizawa;Takako Shiraki-Iida;Ryozo Nagai.
Biochemical and Biophysical Research Communications (1998)

731 Citations

Regulation of oxidative stress by the anti-aging hormone klotho

Masaya Yamamoto;Jeremy D. Clark;Johanne V. Pastor;Prem Gurnani.
Journal of Biological Chemistry (2005)

704 Citations

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

Klementina Fon Tacer;Angie L. Bookout;Xunshan Ding;Hiroshi Kurosu.
Molecular Endocrinology (2010)

659 Citations

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