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D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
20890
World Ranking
4347
National Ranking
2119

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

L. Darryl Quarles is affiliated with the University of Tennessee Health Science Center in the United States. Their research spans key areas within Biochemistry, Genetics and Molecular Biology as well as Medicine, with a strong focus on Molecular Biology, Oncology, Genetics, Nephrology, and Orthopedics and Sports Medicine.

Their work encompasses several main topics, including:

  • Fibroblast Growth Factor Research
  • Parathyroid Disorders and Treatments
  • Bone health and treatments
  • Bone health and osteoporosis research
  • Protein Kinase Regulation and GTPase Signaling
  • Pancreatic function and diabetes
  • Metabolism, Diabetes, and Cancer

Among recent papers, the following are notable for their contribution to understanding bone health and molecular mechanisms:

  • Osteoporosis: Mechanism, Molecular Target and Current Status on Drug Development, 2020, Current Medicinal Chemistry
  • Explaining Divergent Observations Regarding Osteocalcin/GPRC6A Endocrine Signaling, 2021, Endocrinology
  • Role of GPRC6A in Regulating Hepatic Energy Metabolism in Mice, 2020, Scientific Reports
  • The carboxylation status of osteocalcin has important consequences for its structure and dynamics, 2020, Biochimica et Biophysica Acta (BBA) - General Subjects
  • Humanized GPRC6AKGKY is a gain-of-function polymorphism in mice, 2020, Scientific Reports

L. Darryl Quarles frequently collaborates with several researchers, including:

  • Jeremy C. Smith
  • Zhousheng Xiao
  • Min Pi
  • Micholas Dean Smith
  • Rupesh Agarwal

Their research has been published in prominent venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Scientific Reports
  • Current Medicinal Chemistry
  • Endocrinology

L. Darryl Quarles has been recognized as a Member of the Association of American Physicians.

Best Publications

  • Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism

    Jian Q Feng;Leanne M Ward;Shiguang Liu;Yongbo Lu

  • Regulation and Function of the FGF23/Klotho Endocrine Pathways

    Aline Martin;Valentin David;L. Darryl Quarles

  • Fibroblast Growth Factor 23 Is a Counter-Regulatory Phosphaturic Hormone for Vitamin D

    Shiguang Liu;Wen Tang;Jianping Zhou;Jason R. Stubbs

  • Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX.

    Shiguang Liu;Rong Guo;Leigh G. Simpson;Zhou-Sheng Xiao

  • Pathogenic role of Fgf23 in Hyp mice

    Shiguang Liu;Jianping Zhou;Wen Tang;Xi Jiang

  • Endocrine functions of bone in mineral metabolism regulation

    L. Darryl Quarles

  • How Fibroblast Growth Factor 23 Works

    Shiguang Liu;L. Darryl Quarles

  • Hemodialysis-associated subclavian vein stenosis

    Steve J. Schwab;L. Darryl Quarles;John P. Middleton;Richard H. Cohan

  • Achieving NKF-K/DOQI™ bone metabolism and disease treatment goals with cinacalcet HCl

    Sharon M Moe;Glenn M Chertow;Jack W Coburn;L Darryl Quarles

  • FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization.

    L. Darryl Quarles

  • Serum FGF23 Levels in Normal and Disordered Phosphorus Homeostasis

    Thomas J Weber;Shiguang Liu;Olafur S Indridason;L Darryl Quarles

  • Identification of a Novel Extracellular Cation-sensing G-protein-coupled Receptor

    Min Pi;Pieter Faber;George Ekema;P. David Jackson

  • Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD.

    L. Darryl Quarles;Daniel A. Yohay;Barbara A. Carroll;Charles E. Spritzer

  • Role of Hyperphosphatemia and 1,25-Dihydroxyvitamin D in Vascular Calcification and Mortality in Fibroblastic Growth Factor 23 Null Mice

    Jason R. Stubbs;Shiguang Liu;Wen Tang;Jianping Zhou

  • Role of FGF23 in vitamin D and phosphate metabolism: Implications in chronic kidney disease

    L. Darryl Quarles

  • Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

    Aline Martin;Shiguang Liu;Valentin David;Hua Li

  • Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism.

    L. Darryl Quarles

  • The Calcimimetic AMG 073 as a Potential Treatment for Secondary Hyperparathyroidism of End-Stage Renal Disease

    L. Darryl Quarles;Donald J. Sherrard;Stephen Adler;Steven J. Rosansky

  • Cilia-like Structures and Polycystin-1 in Osteoblasts/Osteocytes and Associated Abnormalities in Skeletogenesis and Runx2 Expression

    Zhousheng Xiao;Shiqin Zhang;Josh Mahlios;Gan Zhou

  • Blood Pressure and Mortality in U.S. Veterans With Chronic Kidney Disease: A Cohort Study

    Csaba P. Kovesdy;Anthony J. Bleyer;Miklos Z. Molnar;Jennie Z. Ma

Frequent Co-Authors

Csaba P. Kovesdy
Csaba P. Kovesdy University of Tennessee Health Science Center
Jeremy C. Smith
Jeremy C. Smith University of Tennessee at Knoxville
Kamyar Kalantar-Zadeh
Kamyar Kalantar-Zadeh University of California, Irvine
Robert W. Williams
Robert W. Williams University of Tennessee Health Science Center
Miklos Z. Molnar
Miklos Z. Molnar University of Utah
Lu Lu
Lu Lu University of Tennessee Health Science Center
Lynda F. Bonewald
Lynda F. Bonewald Indiana University
Katherine S. Pollard
Katherine S. Pollard University of California, San Francisco
Hong-Wen Deng
Hong-Wen Deng Tulane University
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami

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