World's Best Scientists 2026 revealed!
Lynda F. Bonewald

Lynda F. Bonewald

Award Badge
Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
112
Citations
44851
World Ranking
818
National Ranking
497

Biology and Biochemistry

D-Index
115
Citations
47190
World Ranking
792
National Ranking
497

Medicine

D-Index
114
Citations
46841
World Ranking
4748
National Ranking
2572

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lynda F. Bonewald is affiliated with Indiana University in the United States and is active in research within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work notably spans molecular biology, physiology, oncology, genetics, and cell biology as subfields of study. The main topics of Bonewald's research include bone metabolism and diseases, adipose tissue and metabolism, muscle physiology and disorders, bone health and treatments, metabolomics and mass spectrometry studies, nutrition and health in aging, as well as bone health and osteoporosis research.

The scientist has contributed to various recent publications. These include:

  • "The Osteocyte: New Insights" (2020), published in Annual Review of Physiology
  • "Quantification of aminobutyric acids and their clinical applications as biomarkers for osteoporosis" (2020), published in Communications Biology
  • "Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection" (2022), published in Nature Communications
  • "Taurine, an osteocyte metabolite, protects against oxidative stress-induced cell death and decreases inhibitors of the Wnt/β-catenin signaling pathway" (2020), published in Bone
  • "Sclerostin Directly Stimulates Osteocyte Synthesis of Fibroblast Growth Factor-23" (2021), published in Calcified Tissue International

Bonewald frequently collaborates with researchers such as Matthew Prideaux, Fabrizio Pin, Marco Brotto, Yukiko Kitase, and Joshua R. Huot. These collaborations have enriched their contributions to the scientific community.

Their publications are often found in venues including bioRxiv (Cold Spring Harbor Laboratory), Bone, Calcified Tissue International, Methods in Molecular Biology, and Proceedings of IMPRS.

Bonewald received the Fellow of the American Association for the Advancement of Science (AAAS) award in 2019.

Best Publications

  • The Amazing Osteocyte

    Lynda F Bonewald

  • Bioactive glass in tissue engineering

    Mohamed N. Rahaman;Delbert E. Day;B. Sonny Bal;Qiang Fu

  • Evidence for osteocyte regulation of bone homeostasis through RANKL expression

    Tomoki Nakashima;Mikihito Hayashi;Takanobu Fukunaga;Kosaku Kurata

  • Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor β

    Keisuke Horiuchi;Norio Amizuka;Sunao Takeshita;Hiroyuki Takamatsu

  • Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism

    Jian Q Feng;Leanne M Ward;Shiguang Liu;Yongbo Lu

  • Osteocytes, mechanosensing and Wnt signaling.

    Lynda F. Bonewald;Mark L. Johnson

  • The Osteocyte: An Endocrine Cell … and More

    Sarah L. Dallas;Matthew Prideaux;Lynda F. Bonewald

  • Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo.

    I. R. Garrett;B. F. Boyce;R. O.C. Oreffo;L. Bonewald

  • Osteocyte Wnt/β-Catenin Signaling Is Required for Normal Bone Homeostasis

    Ina Kramer;Christine Halleux;Hansjoerg Keller;Marco Pegurri

  • Role of transforming growth factor-beta in bone remodeling.

    L F Bonewald;G R Mundy

  • Establishment of an osteocyte-like cell line, MLO-Y4

    Yoichi Kato;Jolene J. Windle;Barbara A. Koop;Gregory R. Mundy

  • Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin.

    Priscilla P. Cherian;Arlene J. Siller-Jackson;Sumin Gu;Xin Wang

  • Osteocytes as Dynamic Multifunctional Cells

    Lynda F. Bonewald

  • Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

    Asiri R. Wijenayaka;Masakazu Kogawa;Hui Peng Lim;Lynda F. Bonewald

  • Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation

    Hai Qing;Laleh Ardeshirpour;Paola Divieti Pajevic;Vladimir Dusevich

  • Proteolysis of Latent Transforming Growth Factor-β (TGF-β)-binding Protein-1 by Osteoclasts A CELLULAR MECHANISM FOR RELEASE OF TGF-β FROM BONE MATRIX

    Sarah L. Dallas;Sarah L. Dallas;Jennifer L. Rosser;Gregory R. Mundy;Lynda F. Bonewald

  • Glucocorticoid-Treated Mice Have Localized Changes in Trabecular Bone Material Properties and Osteocyte Lacunar Size That Are Not Observed in Placebo-Treated or Estrogen-Deficient Mice†

    Nancy E Lane;Wei Yao;Mehdi Balooch;Ravi K Nalla

  • Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

    Hyeonwoo Kim;Christiane D. Wrann;Mark Jedrychowski;Sara Vidoni

  • Identification of Senescent Cells in the Bone Microenvironment

    Joshua N Farr;Daniel G Fraser;Haitao Wang;Katharina Jaehn

  • Mechanosensation and transduction in osteocytes

    Lynda F Bonewald

Frequent Co-Authors

Gregory R. Mundy
Gregory R. Mundy Vanderbilt University
Jian Q. Feng
Jian Q. Feng Texas A&M University
Zvi Schwartz
Zvi Schwartz Virginia Commonwealth University
Barbara D. Boyan
Barbara D. Boyan Virginia Commonwealth University
Jean X. Jiang
Jean X. Jiang The University of Texas Health Science Center at San Antonio
David D Dean
David D Dean The University of Texas Health Science Center at San Antonio
Douglas P. Kiel
Douglas P. Kiel Beth Israel Deaconess Medical Center
Mohamed N. Rahaman
Mohamed N. Rahaman Missouri University of Science and Technology
Jian Huang
Jian Huang University of Iowa
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center

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