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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
21707
World Ranking
10550
National Ranking
4582

Overview

Jean X. Jiang is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research spans across biochemical and medical fields, with a significant focus on molecular biology and related subfields.

The main fields of study for Jiang include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, Jiang's work concentrates on several subfields such as:

  • Molecular Biology
  • Physiology
  • Immunology
  • Oncology
  • Genetics

Jiang has studied a range of specialized topics, including:

  • Connexins and lens biology
  • Heat shock proteins research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Immune cells in cancer
  • Biochemical effects in animals
  • Redox biology and oxidative stress
  • Adenosine and Purinergic Signaling

The researcher has published extensively, with frequent publications appearing in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Redox Biology
  • Bone Research
  • International Journal of Molecular Sciences

Some recent notable papers include:

  • Negative feedback control of neuronal activity by microglia, 2020, Nature
  • In situ mapping identifies distinct vascular niches for myelopoiesis, 2021, Nature
  • LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth, 2021, The Journal of Experimental Medicine
  • Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche, 2022, Immunity
  • Mechanotransduction via the coordinated actions of integrins, PI3K signaling and Connexin hemichannels, 2021, Bone Research

Jiang collaborates frequently with several researchers, including:

  • Sumin Gu
  • Manuel A. Riquelme
  • Rui Hua
  • Francisca M. Acosta
  • Yumeng Quan

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Negative feedback control of neuronal activity by microglia

    Ana Badimon;Hayley J. Strasburger;Pinar Ayata;Xinhong Chen

  • Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin.

    Priscilla P. Cherian;Arlene J. Siller-Jackson;Sumin Gu;Xin Wang

  • ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

    Juan A. Orellana;Nicolas Froger;Pascal Ezan;Jean X. Jiang

  • Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases

    Danielle A. Callaway;Jean X. Jiang

  • Amyloid β-Induced Death in Neurons Involves Glial and Neuronal Hemichannels

    Juan A. Orellana;Kenji F. Shoji;Verónica Abudara;Pascal Ezan

  • Heteromeric connexons in lens gap junction channels.

    Jean X. Jiang;Daniel A. Goodenough

  • Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

    Nidhi Batra;Sirisha Burra;Arlene J. Siller-Jackson;Sumin Gu

  • Biological role of connexin intercellular channels and hemichannels

    Rekha Kar;Nidhi Batra;Manuel A. Riquelme;Jean X. Jiang

  • Expression of functional gap junctions and regulation by fluid flow in osteocyte-like MLO-Y4 cells.

    Benxu Cheng;Shujie Zhao;Jian Luo;Eugene Sprague

  • Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels.

    Sirisha Burra;Daniel P. Nicolella;W. Loren Francis;Christopher J. Freitas

  • Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways

    Yukiko Kitase;Leonardo Barragan;Hai Qing;Shino Kondoh;Shino Kondoh

  • Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor.

    Priscilla P. Cherian;Benxu Cheng;Sumin Gu;Eugene A Sprague

  • Glucocorticoid‐induced autophagy in osteocytes

    Xuechun Xia;Rekha Kar;Jelica Gluhak-Heinrich;Wei Yao

  • Formation of heteromeric gap junction channels by connexins 40 and 43 in vascular smooth muscle cells

    Ding Sheng He;Jean X. Jiang;Steven M. Taffet;Janis M. Burt

  • Gap junction- and hemichannel-independent actions of connexins.

    Jean X. Jiang;Sumin Gu

  • PGE2 Is Essential for Gap Junction-Mediated Intercellular Communication between Osteocyte-Like MLO-Y4 Cells in Response to Mechanical Strain

    Benxu Cheng;Yoichi Kato;Shujie Zhao;Jian Luo

  • Glucose increases intracellular free Ca(2+) in tanycytes via ATP released through connexin 43 hemichannels.

    Juan A. Orellana;Pablo J. Sáez;Christian Cortés-campos;Roberto J. Elizondo

  • Gap junction and hemichannel-independent actions of connexins on cell and tissue functions – An update

    Jade Z. Zhou;Jean X. Jiang

  • Prostaglandin Promotion of Osteocyte Gap Junction Function through Transcriptional Regulation of Connexin 43 by Glycogen Synthase Kinase 3/β-Catenin Signaling

    Xuechun Xia;Nidhi Batra;Qian Shi;Lynda F. Bonewald

Frequent Co-Authors

Juan C. Sáez
Juan C. Sáez University of Valparaíso
Lynda F. Bonewald
Lynda F. Bonewald Indiana University
H. Leighton Grimes
H. Leighton Grimes Cincinnati Children's Hospital Medical Center
Daniel A. Goodenough
Daniel A. Goodenough Harvard University
Thomas W. White
Thomas W. White Stony Brook University
Bruce J. Nicholson
Bruce J. Nicholson The University of Texas Health Science Center at San Antonio
Zhiqiang An
Zhiqiang An The University of Texas Health Science Center at Houston
Nancy E. Lane
Nancy E. Lane University of California, Davis
Brian Herman
Brian Herman The University of Texas Health Science Center at San Antonio
James Douglas Engel
James Douglas Engel University of Michigan–Ann Arbor

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