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Biology and Biochemistry

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71
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19002
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6609
National Ranking
3077

Overview

Zhiqiang An is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on molecular biology, epidemiology, immunology, infectious diseases, and oncology as subfields of study.

Their work covers a range of scientific topics, prominently including monoclonal and polyclonal antibodies research, SARS-CoV-2 and COVID-19 research, cytomegalovirus and herpesvirus research, herpesvirus infections and treatments, immune cell function and interaction, HER2/EGFR in cancer research, and COVID-19 clinical research studies.

Zhiqiang An has contributed to several recent papers published in high-impact journals. Selected titles include:

  • Spike mutation D614G alters SARS-CoV-2 fitness (2020, Nature)
  • Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis (2021, Nature)
  • The N501Y spike substitution enhances SARS-CoV-2 infection and transmission (2021, Nature)
  • Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant (2022, Cell Reports)
  • Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion (2021, Nature)

Their frequent coauthors include Ningyan Zhang, Zhiqiang Ku, Wei Xiong, and Leike Li, reflecting ongoing collaborations within their research community.

Major publication venues for Zhiqiang An's work include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Nature, Cancer Research, and Antibody Therapeutics.

Best Publications

  • Spike mutation D614G alters SARS-CoV-2 fitness.

    Jessica A. Plante;Yang Liu;Jianying Liu;Hongjie Xia

  • TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

    Yingjun Zhao;Xilin Wu;Xiaoguang Li;Lu Lin Jiang

  • Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.

    Bryan A. Johnson;Xuping Xie;Adam L. Bailey;Birte Kalveram

  • Antibody-drug conjugates: recent advances in conjugation and linker chemistries

    Kyoji Tsuchikama;Zhiqiang An

  • The N501Y spike substitution enhances SARS-CoV-2 infection and transmission.

    Yang Liu;Jianying Liu;Kenneth S. Plante;Jessica A. Plante

  • Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci

    Christopher L. Schardl;Carolyn A. Young;Uljana Hesse;Stefan G. Amyotte

  • Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.

    Xiujie Sun;Bogang Wu;Huai-Chin Chiang;Hui Deng

  • Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

    Kai Sun;Jiyoung Park;Olga T. Gupta;William L. Holland

  • LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration

    Mi Deng;Xun Gui;Jaehyup Kim;Li Xie

  • Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy.

    Shangang Zhao;Yi Zhu;Robbie D. Schultz;Na Li

  • Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

    Bryan A. Johnson;Xuping Xie;Birte Kalveram;Kumari G. Lokugamage

  • Evolution of nematode-trapping cells of predatory fungi of the Orbiliaceae based on evidence from rRNA-encoding DNA and multiprotein sequences

    Ying Yang;Ence Yang;Zhiqiang An;Zhiqiang An;Xingzhong Liu

  • A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

    Michael D. Miller;Romas Geleziunas;Elisabetta Bianchi;Simon Lennard

  • IgG2m4, an engineered antibody isotype with reduced Fc function.

    Zhiqiang An;Gail Forrest;Renee Moore;Michael Cukan

  • Trastuzumab Triggers Phagocytic Killing of High HER2 Cancer Cells In Vitro and In Vivo by Interaction with Fcγ Receptors on Macrophages

    Yun Shi;Xuejun Fan;Hui Deng;Randall J. Brezski

  • Molecular phylogenetic relationships of nonpathogenic grass mycosymbionts and clavicipitaceous plant pathogens

    Christopher L. Schardl;Jih Shiou Liu;James F. White;Raphael A. Finkel

  • Antibody therapies for the prevention and treatment of viral infections

    Georgina To'a Salazar;Ningyan Zhang;Tong-Ming Fu;Zhiqiang An

  • Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance.

    Chisato M. Yamazaki;Aiko Yamaguchi;Yasuaki Anami;Wei Xiong

  • Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant

    Yang Liu;Jianying Liu;Bryan A. Johnson;Hongjie Xia

  • Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.

    Jessica A Plante;Yang Liu;Jianying Liu;Hongjie Xia

Frequent Co-Authors

Tong-Ming Fu
Tong-Ming Fu The University of Texas Health Science Center
Gerald F. Bills
Gerald F. Bills The University of Texas Health Science Center at Houston
Xingzhong Liu
Xingzhong Liu Nankai University
Cheng Cheng Zhang
Cheng Cheng Zhang The University of Texas Southwestern Medical Center
Ningshao Xia
Ningshao Xia Xiamen University
Baozhu Guo
Baozhu Guo Agricultural Research Service
Pei-Yong Shi
Pei-Yong Shi GlaxoSmithKline (United Kingdom)
Vineet D. Menachery
Vineet D. Menachery The University of Texas Medical Branch at Galveston
Scott C. Weaver
Scott C. Weaver The University of Texas Medical Branch at Galveston
Anil K. Sood
Anil K. Sood The University of Texas MD Anderson Cancer Center

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