2026 David C. Spray: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	117	731	651	465	404	496	42333

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

117

731

651

465

404

496

42333

Biology and Biochemistry

D-Index

117

Citations

42333

World Ranking

731

National Ranking

465

Overview

David C. Spray is affiliated with the Albert Einstein College of Medicine in the United States. Their research spans multiple disciplines within the biological sciences, with a particular focus on biochemistry, genetics, molecular biology, medicine, and neuroscience. Notably, their work includes a significant number of publications in molecular biology and neurology, reflecting a deep engagement with the cellular and molecular mechanisms underlying health and disease.

The scientist's main fields of study cover:

Biochemistry, Genetics and Molecular Biology
Medicine
Neuroscience

Within these broad areas, Spray's subfields of study include:

Molecular Biology
Neurology
Physiology
Cellular and Molecular Neuroscience
Ophthalmology

Their research themes revolve around key topics such as:

Connexins and lens biology
Neuroscience and Neuropharmacology Research
Neuroinflammation and Neurodegeneration Mechanisms
Barrier Structure and Function Studies
Nicotinic Acetylcholine Receptors Study
Pain Mechanisms and Treatments
Heat shock proteins research

Spray has contributed to numerous publications in scientific journals, with frequent publications appearing in:

bioRxiv (Cold Spring Harbor Laboratory)
Preprints.org
Nature reviews. Neuroscience
Nature Communications
Scientific Reports

Recent notable papers include:

Emerging importance of satellite glia in nervous system function and dysfunction, 2020, Nature Reviews. Neuroscience
Stress gates an astrocytic energy reservoir to impair synaptic plasticity, 2020, Nature Communications
Severe COVID-19 and healthcare-associated infections on the ICU: time to remember the basics?, 2020, Journal of Hospital Infection
Cx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability, 2021, Scientific Reports
Apoptotic Osteocytes Induce RANKL Production in Bystanders via Purinergic Signaling and Activation of Pannexin Channels, 2020, Journal of Bone and Mineral Research

Spray has collaborated frequently with several other researchers, including:

Antonio Cibelli
Eliana Scemes
Randy F. Stout
Sean McCutcheon
Dumitru A. Iacobaş

Best Publications

Gap junctions: new tools, new answers, new questions.

M.V.L. Bennett;L.C. Barrio;T.A. Bargiello;D.C. Spray

1176
Citations
Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions

Juan C. Saez;John A. Connor;David C. Spray;Michael V. L. Bennett

723
Citations
Glial cells in (patho)physiology.

Vladimir Parpura;Michael T. Heneka;Vedrana Montana;Stéphane H.R. Oliet

663
Citations
Differential expression of three gap junction proteins in developing and mature brain tissues

R. Dermietzel;O. Traub;T. K. Hwang;E. Beyer

638
Citations
Gap junctions in the brain: where, what type, how many and why?

Rolf Dermietzel;David C. Spray

624
Citations
Gap junctional conductance is a simple and sensitive function of intracellular pH

D. C. Spray;Andrew Harris;M. V.L. Bennett

554
Citations
Physiology and Pharmacology of Gap Junctions

D. C. Spray;M. V.L. Bennett

549
Citations
Pannexin1 is part of the pore forming unit of the P2X7 receptor death complex

Silviu Locovei;Eliana Scemes;Feng Qiu;David C. Spray

505
Citations
Equilibrium properties of a voltage-dependent junctional conductance.

D. C. Spray;A. L. Harris;M. V.L. Bennett

477
Citations
Gap junctions between cultured astrocytes: immunocytochemical, molecular, and electrophysiological analysis

R Dermietzel;EL Hertberg;JA Kessler;DC Spray

469
Citations
Wnt-1 regulation of connexin43 in cardiac myocytes

Zhaowei Ai;Avi Fischer;David C. Spray;Anthony M.C. Brown

442
Citations
cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide

Juan C. Saez;David C. Spray;Angus C. Nairn;Elliot Hertzberg

430
Citations
P2X7 receptor-Pannexin1 complex: pharmacology and signaling

Rodolfo Iglesias;Silviu Locovei;Andre P Roque;Anael P Alberto;Anael P Alberto

406
Citations
Pannexin 1: The Molecular Substrate of Astrocyte “Hemichannels”

Rodolfo Iglesias;Gerhard Dahl;Feng Qiu;David C. Spray

400
Citations
Potent block of Cx36 and Cx50 gap junction channels by mefloquine.

Scott J. Cruikshank;Matthew Hopperstad;Meg Younger;Barry W. Connors

397
Citations
The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: A “bumper-car” model

Mia M. Thi;John M. Tarbell;Sheldon Weinbaum;David C. Spray

393
Citations
Structure-activity relations of the cardiac gap junction channel.

D. C. Spray;J. M. Burt

384
Citations
Functional connexin "hemichannels": a critical appraisal.

David C. Spray;Zu Cheng Ye;Bruce R. Ransom

382
Citations
Use of Organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damage of auditory hair cells

Kopke Rd;Liu W;Gabaizadeh R;Jacono A

378
Citations
Pannexin channels are not gap junction hemichannels

Gina E. Sosinsky;Daniela Boassa;Rolf Dermietzel;Heather S. Duffy

376
Citations