World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
82
Citations
19462
World Ranking
1533
National Ranking
83

Medicine

D-Index
82
Citations
19469
World Ranking
16324
National Ranking
683

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Neuron
  • Central nervous system

James I. Nagy mainly investigates Gap junction, Connexin, Neuroscience, Astrocyte and Cell biology. His Gap junction research is multidisciplinary, relying on both Immunogold labelling, Cellular localization, Neuroglia and Oligodendrocyte. The study incorporates disciplines such as Cell junction and Neuron in addition to Neuroglia.

His Oligodendrocyte study integrates concerns from other disciplines, such as Molecular biology and Connexon. His research on Neuroscience frequently connects to adjacent areas such as gamma-Aminobutyric acid. His Astrocyte study incorporates themes from Cell type and Ependymal Cell, Spinal cord.

His most cited work include:

  • The nucleus basalis magnocellularis: the origin of a cholinergic projection to the neocortex of the rat. (584 citations)
  • Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin. (341 citations)
  • Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS (337 citations)

What are the main themes of his work throughout his whole career to date?

James I. Nagy focuses on Gap junction, Cell biology, Neuroscience, Connexin and Internal medicine. The Gap junction study combines topics in areas such as Cell junction, Neuroglia, Astrocyte and Oligodendrocyte. Connexon is closely connected to Neuron in his research, which is encompassed under the umbrella topic of Astrocyte.

His research investigates the connection between Cell biology and topics such as Biochemistry that intersect with problems in Biophysics. His Internal medicine research is multidisciplinary, incorporating perspectives in Endocrinology and Spinal cord. His Spinal cord research is multidisciplinary, incorporating elements of Capsaicin and Substance P.

He most often published in these fields:

  • Gap junction (41.51%)
  • Cell biology (31.60%)
  • Neuroscience (26.89%)

What were the highlights of his more recent work (between 2010-2020)?

  • Gap junction (41.51%)
  • Electrical Synapses (15.09%)
  • Neuroscience (26.89%)

In recent papers he was focusing on the following fields of study:

James I. Nagy spends much of his time researching Gap junction, Electrical Synapses, Neuroscience, Cell biology and Connexin. He has included themes like Nucleus, Neurotransmission, Knockout mouse, Genetically modified mouse and Spinal cord in his Gap junction study. His Electrical Synapses research includes themes of Axon terminal and Electrophysiology.

His work on Axon, Hippocampal formation and Neural Conduction as part of general Neuroscience study is frequently connected to Mauthner cell and Central pattern generator, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. James I. Nagy interconnects Trabecular meshwork and Central nervous system in the investigation of issues within Cell biology. His research in Connexin intersects with topics in Midbrain, Immunogold labelling, Astrocyte and Pathology.

Between 2010 and 2020, his most popular works were:

  • Synergy between electrical coupling and membrane properties promotes strong synchronization of neurons of the mesencephalic trigeminal nucleus (73 citations)
  • Molecular and functional asymmetry at a vertebrate electrical synapse (60 citations)
  • Electrical synapses in mammalian CNS: Past eras, present focus and future directions. (40 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Neuron
  • Enzyme

His primary areas of investigation include Gap junction, Electrical Synapses, Neuroscience, Connexin and Spinal cord. His work carried out in the field of Gap junction brings together such families of science as Biological neural network, Nerve net and Nanotechnology. His Electrical Synapses study is focused on Cell biology in general.

The concepts of his Neuroscience study are interwoven with issues in Immunolabeling and Anatomy. His Connexin study combines topics from a wide range of disciplines, such as Genetically modified mouse, Neurotransmission, Parenchyma and Oligodendrocyte. His Spinal cord study combines topics in areas such as Stimulation and Brainstem.

Best Publications

  • The nucleus basalis magnocellularis: the origin of a cholinergic projection to the neocortex of the rat.

    John Lehmann;J.I. Nagy;S. Atmadja;H.C. Fibiger

  • Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin.

    J.I. Nagy;S.P. Hunt;L.L. Iversen;P.C. Emson

  • Cell-specific expression of connexins and evidence of restricted gap junctional coupling between glial cells and between neurons.

    John E. Rash;Thomas Yasumura;F. Edward Dudek;James I. Nagy

  • Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS

    James I Nagy;John E Rash

  • Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat

    JI Nagy;LL Iversen;M Goedert;D Chapman

  • Connexin30 in rodent, cat and human brain: selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance.

    J.I Nagy;D Patel;P.A.Y Ochalski;G.L Stelmack

  • Neurotoxic action of capsaicin on spinal substance P neurons.

    J.I. Nagy;S.R. Vincent;W.M.A. Staines;H.C. Fibinger

  • Update on connexins and gap junctions in neurons and glia in the mammalian nervous system.

    James I. Nagy;F.Edward Dudek;John E. Rash

  • Fluoride-resistant acid phosphatase-containing neurones in dorsal root ganglia are separate from those containing substance P or somatostatin

    J.I. Nagy;S.P. Hunt

  • On the organization of astrocytic gap junctions in rat brain as suggested by LM and EM immunohistochemistry of connexin43 expression.

    T. Yamamoto;A. Ochalski;E. L. Hertzberg;J. I. Nagy

  • Immunogold evidence that neuronal gap junctions in adult rat brain and spinal cord contain connexin-36 but not connexin-32 or connexin-43

    J. E. Rash;W. A. Staines;T. Yasumura;D. Patel

  • Anterior striatal projections to the globus pallidus, entopeduncular nucleus and substantia nigra in the rat: the GABA connection.

    J.I. Nagy;D.A. Carter;H.C. Fibiger

  • Direct evidence for presynaptic and postsynaptic dopamine receptors in brain

    J. I. Nagy;T. Lee;P. Seeman;H. C. Fibiger

  • LM and EM immunolocalization of the gap junctional protein connexin 43 in rat brain.

    T. Yamamoto;A. Ochalski;E.L. Hertzberg;J.I. Nagy

  • Identification of cells expressing Cx43, Cx30, Cx26, Cx32 and Cx36 in gap junctions of rat brain and spinal cord.

    J. E. Rash;T. Yasumura;K. G. V. Davidson;C. S. Furman

  • Elevated connexin43 immunoreactivity at sites of amyloid plaques in Alzheimer's disease.

    J.I. Nagy;W. Li;E.L. Hertzberg;C.A. Marotta

  • Connexin26 in adult rodent central nervous system: Demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43

    James I. Nagy;Xinbo Li;Jeremy Rempel;Gerald Stelmack

  • CONNEXIN-47 AND CONNEXIN-32 IN GAP JUNCTIONS OF OLIGODENDROCYTE SOMATA, MYELIN SHEATHS, PARANODAL LOOPS AND SCHMIDT-LANTERMAN INCISURES: IMPLICATIONS FOR IONIC HOMEOSTASIS AND POTASSIUM SIPHONING

    N. Kamasawa;A. Sik;M. Morita;T. Yasumura

  • Coupling of Astrocyte Connexins Cx26, Cx30, Cx43 to Oligodendrocyte Cx29, Cx32, Cx47: Implications From Normal and Connexin32 Knockout Mice

    J.I. Nagy;A.-V. Ionescu;B.D. Lynn;J.E. Rash

  • Immunohistochemistry of adenosine deaminase: implications for adenosine neurotransmission.

    JI Nagy;LA LaBella;M Buss;PE Daddona

Frequent Co-Authors

John E. Rash
John E. Rash Colorado State University
Jonathan D. Geiger
Jonathan D. Geiger University of Manitoba
Hans C. Fibiger
Hans C. Fibiger University of British Columbia
Klaus Willecke
Klaus Willecke University of Bonn
Michel Goedert
Michel Goedert MRC Laboratory of Molecular Biology
Henry I. Yamamura
Henry I. Yamamura University of Arizona
Leslie L. Iversen
Leslie L. Iversen University of Oxford
Steven R. Vincent
Steven R. Vincent University of British Columbia
F. Edward Dudek
F. Edward Dudek University of Utah
Michael V. L. Bennett
Michael V. L. Bennett Albert Einstein College of Medicine

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