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Jonathan D. Geiger

Jonathan D. Geiger

D-Index & Metrics

Neuroscience

D-Index
64
Citations
13640
World Ranking
3291
National Ranking
193

Overview

Jonathan D. Geiger is affiliated with the University of Manitoba in Canada. Their research spans multiple fields with a primary focus on Medicine and Biochemistry, Genetics, and Molecular Biology. Within these disciplines, Geiger has contributed notably to subfields such as Physiology, Epidemiology, Virology, Cell Biology, and Molecular Biology.

The scientist's work centers around several main topics including:

  • Calcium signaling and nucleotide metabolism
  • Autophagy in Disease and Therapy
  • HIV Research and Treatment
  • Mosquito-borne diseases and control
  • Cellular transport and secretion
  • Long-Term Effects of COVID-19
  • Lysosomal Storage Disorders Research

Jonathan D. Geiger has published extensively in notable scientific journals. Frequent publication venues include:

  • Journal of Pharmacology and Experimental Therapeutics
  • Journal of Neuroimmune Pharmacology
  • Frontiers in Pharmacology
  • Viruses
  • The FASEB Journal

Recent papers authored or co-authored by Geiger reflect a focus on cellular function, infectious diseases, and therapeutic mechanisms. Selected publications include:

  • "Lysosomal Stress Response (LSR): Physiological Importance and Pathological Relevance," 2021, Journal of Neuroimmune Pharmacology
  • "Overcoming Chemoresistance: Altering pH of Cellular Compartments by Chloroquine and Hydroxychloroquine," 2021, Frontiers in Cell and Developmental Biology
  • "Role of Endolysosomes in Severe Acute Respiratory Syndrome Coronavirus-2 Infection and Coronavirus Disease 2019 Pathogenesis: Implications for Potential Treatments," 2020, Frontiers in Pharmacology
  • "Janus sword actions of chloroquine and hydroxychloroquine against COVID-19," 2020, Cellular Signalling
  • "Two-pore channels regulate Tat endolysosome escape and Tat-mediated HIV-1 LTR transactivation," 2020, The FASEB Journal

The collaborative nature of Geiger's research is evident through frequent co-authors, who have contributed to numerous publications together. These co-authors include:

  • Peter W. Halcrow
  • Nabab Khan
  • Xuesong Chen
  • Nirmal Kumar
  • Zahra Afghah

Best Publications

  • Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet.

    Kristopher J. Bough;Kristopher J. Bough;Jonathon Wetherington;Bjørnar Hassel;Jean Francois Pare

  • Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

    Mark P Mattson;Frank M LaFerla;Sic L Chan;Malcolm A Leissring

  • Presenilin-1 Mutations Increase Levels of Ryanodine Receptors and Calcium Release in PC12 Cells and Cortical Neurons

    Sic L. Chan;Michael Mayne;Clark P. Holden;Jonathan D. Geiger

  • Dietary supplement creatine protects against traumatic brain injury.

    Patrick G. Sullivan;Jonathan D. Geiger;Jonathan D. Geiger;T. Mark P. Mattson;Stephen W. Scheff

  • Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic.

    Avindra Nath;Karen Psooy;Carol Martin;Bodo Knudsen

  • Brain Glycogen Decreases with Increased Periods of Wakefulness: Implications for Homeostatic Drive to Sleep

    Jiming Kong;P. Nicolas Shepel;Clark P. Holden;Mirek Mackiewicz

  • Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.

    David S. K. Magnuson;Bodo E. Knudsen;Jonathan D. Geiger;Robert M. Brownstone

  • Neurobiological aspects of human immunodeficiency virus infection: neurotoxic mechanisms.

    Avindra Nath;Jonathan Geiger

  • HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity.

    N. J. Haughey;N. J. Haughey;A. Nath;M. P. Mattson;J. T. Slevin

  • Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine.

    Avindra Nath;Norman J. Haughey;Melina Jones;Caroline Anderson

  • Adenosine A2A receptors and brain injury: Broad spectrum of neuroprotection, multifaceted actions and “fine tuning” modulation

    Jiang Fan Chen;Patricia K. Sonsalla;Felicita Pedata;Alessia Melani

  • Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.

    N. J. Haughey;C.P. Holden;A. Nath;J.D. Geiger

  • Tumor necrosis factor‐α‐induced neutral sphingomyelinase‐2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors

    David Wheeler;Edward Knapp;Veera V.R. Bandaru;Yue Wang

  • Caffeine protects against MPTP‐induced blood‐brain barrier dysfunction in mouse striatum

    Unknown

  • Adenosine A2A receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage

    Michael Mayne;Julie Fotheringham;Hui Jin Yan;Christopher Power

  • Presence and functional significance of presynaptic ryanodine receptors.

    Ron Bouchard;Roberto Pattarini;Jonathan D. Geiger

  • Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet

    Jaya R.P. Prasanthi;Bhanu Dasari;Gurdeep Marwarha;Tyler Larson

  • Neuronal excitatory properties of human immunodeficiency virus type 1 tat protein

    J Cheng;A Nath;B Knudsen;S Hochman

  • Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

    Xuesong Chen;Jeremy W Gawryluk;John F Wagener;Othman Ghribi

  • Characterization and localization of adenosine receptors in rat spinal cord

    JD Geiger;FS LaBella;JI Nagy

  • Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases.

    Xuesong Chen;Othman Ghribi;Jonathan D. Geiger

Frequent Co-Authors

James I. Nagy
James I. Nagy University of Manitoba
Norman J. Haughey
Norman J. Haughey Tulane University
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
David S.K. Magnuson
David S.K. Magnuson University of Louisville
Robert M. Brownstone
Robert M. Brownstone University College London
Shawn Hochman
Shawn Hochman Emory University
Murray B. Stein
Murray B. Stein University of California, San Diego

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