World's Best Scientists 2026 revealed!
Norman J. Haughey

Norman J. Haughey

D-Index & Metrics

Neuroscience

D-Index
71
Citations
17255
World Ranking
2418
National Ranking
1142

Biology and Biochemistry

D-Index
71
Citations
17288
World Ranking
6677
National Ranking
3105

Overview

Norman J. Haughey is affiliated with the Johns Hopkins University School of Medicine in the United States. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, contributing an extensive body of work focused on molecular mechanisms and cellular processes.

The primary areas of study for this scientist include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their work delves into specific subfields such as:

  • Molecular Biology
  • Physiology
  • Neurology
  • Virology
  • Emergency Medicine

The main topics addressed in their publications highlight several key research themes:

  • Extracellular vesicles in disease
  • HIV Research and Treatment
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Sphingolipid Metabolism and Signaling
  • HIV-related health complications and treatments
  • HIV/AIDS Research and Interventions
  • Diet and metabolism studies

The scientist has contributed to various journals and publication venues, frequently publishing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Extracellular Vesicles
  • Proceedings of the National Academy of Sciences
  • Alzheimer's & Dementia
  • Multiple Sclerosis Journal

Some of their recent published papers include:

  • Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches, 2024, Journal of Extracellular Vesicles
  • Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms, 2021, Journal of Extracellular Vesicles
  • Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles, 2020, Journal of Extracellular Vesicles
  • Cx43 hemichannels contribute to astrocyte-mediated toxicity in sporadic and familial ALS, 2022, Proceedings of the National Academy of Sciences
  • Nipping disease in the bud: nSMase2 inhibitors as therapeutics in extracellular vesicle-mediated diseases, 2021, Drug Discovery Today

Their collaborative work includes frequent coauthors such as:

  • Pragney Deme
  • Barbara S. Slusher
  • Rana Rais
  • Ajit G. Thomas
  • Raha Dastgheyb

Best Publications

  • HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

    Deanna Saylor;Alex M. Dickens;Ned Sacktor;Norman Haughey

  • Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

    Inna I. Kruman;T. S. Kumaravel;Althaf Lohani;Ward A. Pedersen

  • Disruption of neurogenesis by amyloid β-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease

    Norman J. Haughey;Avi Nath;Sic L. Chan;A. C. Borchard

  • Human immunodeficiency virus-associated dementia: An evolving disease

    Justin C McArthur;Norman Haughey;Suzanne Gartner;Kathy Conant

  • Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4

    TracyAnn Perry;Norman J. Haughey;Mark P. Mattson;Josephine M. Egan

  • Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.

    Louise D Mccullough;Liejun Wu;Norman Haughey;Xibin Liang

  • Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic.

    Avindra Nath;Karen Psooy;Carol Martin;Bodo Knudsen

  • Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease.

    Norman J. Haughey;Dong Liu;Avi Nath;Amy C. Borchard

  • Cell death in HIV dementia.

    M P Mattson;M P Mattson;N J Haughey;A Nath

  • HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity.

    N. J. Haughey;N. J. Haughey;A. Nath;M. P. Mattson;J. T. Slevin

  • Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis.

    Norman J. Haughey;Veera V.R. Bandaru;Mihyun Bae;Mark P. Mattson

  • Perturbation of sphingolipid metabolism and ceramide production in HIV-dementia.

    Norman J. Haughey;Norman J. Haughey;Roy G. Cutler;Anita Tamara;Justin C. McArthur

  • Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine.

    Avindra Nath;Norman J. Haughey;Melina Jones;Caroline Anderson

  • Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions

    Alex M. Dickens;Luis B. Tovar-Y-Romo;Seung Wan Yoo;Amanda L. Trout

  • Plasma Ceramide and Glucosylceramide Metabolism Is Altered in Sporadic Parkinson's Disease and Associated with Cognitive Impairment: A Pilot Study

    Michelle M. Mielke;Walter Maetzler;Norman J. Haughey;Veera V.R. Bandaru

  • Erratum: HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

    Deanna Saylor;Alex M. Dickens;Ned Sacktor;Norman Haughey

  • Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120.

    Norman J. Haughey;Mark P. Mattson;Mark P. Mattson

  • Serum ceramides increase the risk of Alzheimer disease: The Women's Health and Aging Study II

    Michelle M. Mielke;Veera Vankata Ratnam Bandaru;Norman J. Haughey;Jin Xia

  • Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.

    N. J. Haughey;C.P. Holden;A. Nath;J.D. Geiger

  • Tumor necrosis factor‐α‐induced neutral sphingomyelinase‐2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors

    David Wheeler;Edward Knapp;Veera V.R. Bandaru;Yue Wang

Frequent Co-Authors

Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Avindra Nath
Avindra Nath National Institutes of Health
Justin C. McArthur
Justin C. McArthur Johns Hopkins University School of Medicine
Barbara S. Slusher
Barbara S. Slusher Johns Hopkins University School of Medicine
Nathan Herrmann
Nathan Herrmann Sunnybrook Health Science Centre
Jonathan D. Geiger
Jonathan D. Geiger University of Manitoba
Kenneth W. Witwer
Kenneth W. Witwer Johns Hopkins University
Constantine G. Lyketsos
Constantine G. Lyketsos Johns Hopkins University
Peter A. Calabresi
Peter A. Calabresi Johns Hopkins University School of Medicine

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