Pamela E. Knapp

Best Publications

• Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury.

  Joe E. Springer;Robert D. Azbill;Pamela E. Knapp

  552
  Citations

• Synergistic increases in intracellular Ca2+, and the release of MCP-1, RANTES, and IL-6 by astrocytes treated with opiates and HIV-1 Tat.

  Nazira El-Hage;Julie A. Gurwell;Indrapal N. Singh;Pamela E. Knapp

  247
  Citations

• Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

  Nitai C Hait;Laura E Wise;Jeremy C Allegood;Megan O'Brien

  233
  Citations

• Oligodendroglial cell death in jimpy mice: an explanation for the myelin deficit

  Unknown

  224
  Citations

• Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes.

  Tian-Yong Zhao;Shi-Ping Zou;Pamela E. Knapp

  218
  Citations

• Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

  Sylvia Fitting;Bogna M. Ignatowska-Jankowska;Cecilia Bull;Robert P. Skoff

  194
  Citations

• Cultured oligodendrocytes mimic in vivo phenotypic characteristics: Cell shape, expression of myelin-specific antigens, and membrane production☆

  P.E. Knapp;W.P. Bartlett;R.P. Skoff

  191
  Citations

• Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV‐1 tat transgenic mice

  Annadora J. Bruce-Keller;Jadwiga Turchan-Cholewo;Eric J. Smart;Theresa Geurin

  177
  Citations

• Division of astroblasts and oligodendroblasts in postnatal rodent brain: evidence for separate astrocyte and oligodendrocyte lineages.

  Robert P. Skoff;Pamela E. Knapp

  170
  Citations

• HIV-1 Tat and opiate-induced changes in astrocytes promote chemotaxis of microglia through the expression of MCP-1 and alternative chemokines.

  Nazira El-Hage;Guanghan Wu;Juan Wang;Jayakrishna Ambati

  166
  Citations

• Rat Nucleus Accumbens Core Astrocytes Modulate Reward and the Motivation to Self-Administer Ethanol after Abstinence

  Cecilia Bull;Kelen C C Freitas;Shiping Zou;Ryan S Poland

  158
  Citations

• Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons.

  Sylvia Fitting;Ruqiang Xu;Cecilia Bull;Shreya K. Buch

  155
  Citations

• Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD.

  Annadora J Bruce-Keller;James W Geddes;Pamela E Knapp;Robert W McFall

  145
  Citations

• Opioid System Diversity in Developing Neurons, Astroglia and Oligodendroglia in the Subventricular Zone and Striatum: Impact on Gliogenesis In Vivo

  Anne Stiene-Martin;Pamela E. Knapp;Kenneth Martin;Julie A. Gurwell

  142
  Citations

• Prodynorphin Mutations Cause the Neurodegenerative Disorder Spinocerebellar Ataxia Type 23

  Georgy Bakalkin;Hiroyuki Watanabe;Justyna Jezierska;Cloë Depoorter

  135
  Citations

• Morphine Exacerbates HIV-1 Tat-Induced Cytokine Production in Astrocytes through Convergent Effects on [Ca2+]i, NF-κB Trafficking and Transcription

  Nazira El-Hage;Annadora J. Bruce-Keller;Tatiana Yakovleva;Igor Bazov

  135
  Citations

• Morphine and HIV-Tat increase microglial-free radical production and oxidative stress: possible role in cytokine regulation.

  Jadwiga Turchan-Cholewo;Filomena O. Dimayuga;Sunita Gupta;Jeffrey N. Keller

  135
  Citations

• Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: Differential involvement of caspase-3 and endonuclease G.

  Indrapal N Singh;Robin J Goody;Celeste Dean;Nael M Ahmad

  133
  Citations

• Endogenous opioid system in developing normal and jimpy oligodendrocytes: mu and kappa opioid receptors mediate differential mitogenic and growth responses.

  Pamela E. Knapp;Katalin Maderspach;Kurt F. Hauser

  122
  Citations

• Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at µ-opioid receptor-expressing glia

  Shiping Zou;Sylvia Fitting;Yun-Kyung Hahn;Sandra P. Welch

  119
  Citations

• HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse.

  Kurt F. Hauser;Nazira El-Hage;Anne Stiene-Martin;William F. Maragos

  118
  Citations

• Opiate Drug Use and the Pathophysiology of NeuroAIDS

  Kurt F Hauser;Sylvia Fitting;Seth M Dever;Elizabeth M Podhaizer

  116
  Citations

• Pathobiology of dynorphins in trauma and disease

  Kurt F. Hauser;Jane V. Aldrich;Kevin J. Anderson;Georgy Bakalkin

  112
  Citations