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Biology and Biochemistry

D-Index
73
Citations
17013
World Ranking
6013
National Ranking
383

Overview

Kazuhiro Ikenaka is affiliated with the National Institutes of Natural Sciences in Japan, focusing on various aspects of neuroscience and molecular biology. Their research spans primary fields such as Neuroscience and Biochemistry, Genetics and Molecular Biology, with significant contributions in multiple subfields including Molecular Biology, Neurology, Immunology, Developmental Neuroscience, and Cellular and Molecular Neuroscience.

The research topics covered by Ikenaka include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • RNA regulation and disease
  • Interferon and immune responses
  • Barrier Structure and Function Studies
  • Glycosylation and Glycoproteins Research
  • Botulinum Toxin and Related Neurological Disorders

Their recent publications illustrate a wide range of investigative focus areas and venues:

  • Erratic and blood vessel-guided migration of astrocyte progenitors in the cerebral cortex, 2022, Nature Communications
  • A Myelin Galactolipid, Sulfatide, Is Essential for Maintenance of Ion Channels on Myelinated Axon But Not Essential for Initial Cluster Formation, 2021, UNC Libraries
  • Early Maternal and Social Deprivation Expands Neural Stem Cell Population Size and Reduces Hippocampus/Amygdala-Dependent Fear Memory, 2020, Frontiers in Neuroscience
  • A Potential Serum N-glycan Biomarker for Hepatitis C Virus-Related Early-Stage Hepatocellular Carcinoma with Liver Cirrhosis, 2020, International Journal of Molecular Sciences
  • Fut9 Deficiency Causes Abnormal Neural Development in the Mouse Cerebral Cortex and Retina, 2022, Neurochemical Research

Frequent publication venues for Ikenaka include:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Journal of Neurochemistry
  • Nature Communications
  • International Journal of Molecular Sciences
  • Neurochemical Research

Their research often involves collaboration with several co-authors, notable among them are:

  • Eiji Shigetomi (7 joint publications)
  • Schuichi Koizumi (7 joint publications)
  • Kenji F. Tanaka (6 joint publications)
  • Kenji Kobayashi (4 joint publications)
  • Seiji Hitoshi (3 joint publications)

Kazuhiro Ikenaka's scientific output reflects a thorough integration of molecular and cellular neuroscience methods, often addressing mechanisms of neural development, immune responses in the nervous system, and molecular markers related to neurological disorders. Their work contributes to the understanding of processes such as astrocyte migration, myelin function, neural stem cell dynamics, and biomarkers for disease states associated with neurodegeneration and hepatic pathology.

Best Publications

  • The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons

    Masaharu Ogawa;Takaki Miyata;Kazunori Nakajimat;Kenichi Yagyu

  • Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7 Ca2+-PERMEABLE CATION CHANNEL THAT IS CONSTITUTIVELY ACTIVATED AND ENHANCED BY STIMULATION OF G PROTEIN-COUPLED RECEPTOR

    Takaharu Okada;Ryuji Inoue;Kazuto Yamazaki;Akito Maeda

  • The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.

    Hirohide Takebayashi;Yoko Nabeshima;Shosei Yoshida;Osamu Chisaka

  • Glutamate Transporter GLAST Is Expressed in the Radial Glia–Astrocyte Lineage of Developing Mouse Spinal Cord

    Takashi Shibata;Keiko Yamada;Masahiko Watanabe;Kazuhiro Ikenaka

  • Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation

    Youichi Shinozaki;Keisuke Shibata;Keitaro Yoshida;Eiji Shigetomi

  • Multiple Restricted Origin of Oligodendrocytes

    N. Spassky;C. Goujet-Zalc;E. Parmantier;C. Olivier

  • Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene.

    Tetsushi Kagawa;Kazuhiro Ikenaka;Yoshiro Inoue;Shigeki Kuriyama

  • A Myelin Galactolipid, Sulfatide, Is Essential for Maintenance of Ion Channels on Myelinated Axon But Not Essential for Initial Cluster Formation

    Tomoko Ishibashi;Jeffrey L. Dupree;Kazuhiro Ikenaka;Yukie Hirahara

  • A-Type K+ Current Mediated by the Kv4 Channel Regulates the Generation of Action Potential in Developing Cerebellar Granule Cells

    Riichi Shibata;Kensuke Nakahira;Koji Shibasaki;Yoshihiko Wakazono

  • Effect of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil.

    Setsuro Fujii;Kazuhiro Ikenaka;Masakazu Fukushima;Tetsuhiko Shirasaka

  • EFFECT OF COADMINISTRATION OF URACIL OR CYTOSINE ON THE ANTITUMOR ACTIVITY OF CLINICAL DOSES OF 1-(2-TETRAHYDROFURYL)-5-FLUOROURACIL AND LEVEL OF 5-FLUOROURACIL IN RODENTS

    Setsuro Fujii;Shizuo Kitano;Kazuhiro Ikenaka;Tetsuhiko Shirasaka

  • Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells

    Noritaka Masahira;Hirohide Takebayashi;Katsuhiko Ono;Keisuke Watanabe

  • Primary characterization of the protein products of the Escherichia coli ompB locus: structure and regulation of synthesis of the OmpR and EnvZ proteins.

    D E Comeau;K Ikenaka;K L Tsung;M Inouye

  • CHEMICAL SYNTHESIS OF N-ACETYLMURAMYL PEPTIDES WITH PARTIAL STRUCTURES OF BACTERIAL CELL WALL AND THEIR ANALOGS IN RELATION TO IMMUNOADJUVANT ACTIVITIES

    Shoichi Kusumoto;Yuzo Tarumi;Kazuhiro Ikenaka;Tetsuo Shiba

  • Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system.

    Kenji F. Tanaka;Kenji F. Tanaka;Ko Matsui;Takuya Sasaki;Hiromi Sano

  • Effect of uracil on metabolism of 5-fluorouracil in vitro.

    Kazuhiro Ikenaka;Tetshuhiko Shirasaka;Shizuo Kitano;Setsuro Fujii

  • Selective expression of DM-20, an alternatively spliced myelin proteolipid protein gene product, in developing nervous system and in nonglial cells.

    Kazuhiro Ikenaka;Tetsushi Kagawa;Katsuhiko Mikoshiba;Katsuhiko Mikoshiba

  • Interaction of a transcriptional activator, OmpR, with reciprocally osmoregulated genes, ompF and ompC, of Escherichia coli.

    S Norioka;G Ramakrishnan;K Ikenaka;M Inouye

  • Anti-human Olig2 antibody as a useful immunohistochemical marker of normal oligodendrocytes and gliomas.

    Hideaki Yokoo;Sumihito Nobusawa;Hirohide Takebayashi;Kazuhiro Ikenaka

  • Multiple Restricted Origin of Oligodendrocytes

    N Spassky;C Goujet-Zalc;E Parmantier;S Martinez

Frequent Co-Authors

Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University
Kenji F. Tanaka
Kenji F. Tanaka Keio University
Kazunori Nakajima
Kazunori Nakajima Keio University
Saburo Aimoto
Saburo Aimoto Osaka University
Schuichi Koizumi
Schuichi Koizumi University of Yamanashi
Hideyuki Okano
Hideyuki Okano Keio University
Yoshiro Inoue
Yoshiro Inoue Hokkaido University
Bernard Zalc
Bernard Zalc Grenoble Alpes University
Tetsuo Shiba
Tetsuo Shiba Osaka University
Masayori Inouye
Masayori Inouye Rutgers, The State University of New Jersey

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