World's Best Scientists 2026 revealed!
Hideyuki Okano

Hideyuki Okano

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Molecular Biology
Japan
2026
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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
158
Citations
93129
World Ranking
69
National Ranking
5

Medicine

D-Index
162
Citations
100083
World Ranking
714
National Ranking
11

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Japan Leader Award
  • 2025 - Research.com Molecular Biology in Japan Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award
  • 2023 - Research.com Molecular Biology in Japan Leader Award
  • 2023 - Research.com Neuroscience in Japan Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2022 - Research.com Neuroscience in Japan Leader Award

Overview

Hideyuki Okano is affiliated with Keio University in Japan. Their research spans multiple domains within biological and medical sciences, particularly focusing on molecular biology, neuroscience, and genetics.

The scientist's main fields of study include Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. More specifically, their work is concentrated in the subfields of Molecular Biology, Cellular and Molecular Neuroscience, Neurology, Genetics, and Cognitive Neuroscience.

Okano's research covers several key topics, notably Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, Neurogenesis and neuroplasticity mechanisms, Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, Nerve injury and regeneration, as well as Neuroscience and Neuropharmacology Research.

Their recent publications illustrate a broad investigative scope across biology and medicine:

  • The liver-brain-gut neural arc maintains the Treg cell niche in the gut, 2020, Nature
  • iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders, 2022, Cell Stem Cell
  • Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset, 2020, Science
  • First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol, 2021, Regenerative Therapy
  • Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages, 2020, Nature Communications

Frequent co-authors collaborating with Hideyuki Okano include:

  • Masaya Nakamura
  • Narihito Nagoshi
  • Junichi Hata
  • Satoru Morimoto
  • Shinsuke Shibata

Okano's work is often published in venues specializing in biology and medicine, with repeated contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Stem Cell Research
  • Scientific Reports
  • Inflammation and Regeneration
  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Best Publications

  • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

    Taichi Hara;Kenji Nakamura;Makoto Matsui;Makoto Matsui;Makoto Matsui;Akitsugu Yamamoto

  • Variation in the safety of induced pluripotent stem cell lines

    Kyoko Miura;Yohei Okada;Takashi Aoi;Aki Okada

  • Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.

    Seiji Okada;Masaya Nakamura;Hiroyuki Katoh;Tamaki Miyao

  • Asymmetric Inheritance of Radial Glial Fibers by Cortical Neurons

    Takaki Miyata;Ayano Kawaguchi;Hideyuki Okano;Masaharu Ogawa

  • New neurons follow the flow of cerebrospinal fluid in the adult brain.

    Kazunobu Sawamoto;Hynek Wichterle;Oscar Gonzalez-Perez;Jeremy A. Cholfin

  • Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow

    Satoru Morikawa;Yo Mabuchi;Yoshiaki Kubota;Yasuo Nagai

  • Subventricular Zone-Derived Neuroblasts Migrate and Differentiate into Mature Neurons in the Post-Stroke Adult Striatum

    Toru Yamashita;Mikiko Ninomiya;Mikiko Ninomiya;Pilar Hernández Acosta;Jose Manuel García-Verdugo

  • In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus.

    Neeta Singh Roy;Su Wang;Li Jiang;Jian Kang

  • Generation of transgenic non-human primates with germline transmission

    Erika Sasaki;Hiroshi Suemizu;Akiko Shimada;Kisaburo Hanazawa

  • Transplantation of in vitro‐expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

    Y. Ogawa;K. Sawamoto;K. Sawamoto;T. Miyata;S. Miyao

  • Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction

    Hiroshi Kawada;Jun Fujita;Kentaro Kinjo;Yumi Matsuzaki

  • Modeling familial Alzheimer’s disease with induced pluripotent stem cells

    Takuya Yagi;Daisuke Ito;Yohei Okada;Wado Akamatsu

  • Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell.

    Shin Ichi Sakakibara;Shin Ichi Sakakibara;Takao Imai;Takao Imai;Kayoko Hamaguchi;Masataka Okabe;Masataka Okabe

  • Musashi1: An evolutionally conserved marker for CNS progenitor cells including neural stem cells

    Y. Kaneko;S. Sakakibara;T. Imai;A. Suzuki

  • Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury

    Osahiko Tsuji;Kyoko Miura;Yohei Okada;Kanehiro Fujiyoshi

  • Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice

    Satoshi Nori;Yohei Okada;Akimasa Yasuda;Osahiko Tsuji

  • Identification of a putative intestinal stem cell and early lineage marker; musashi-1.

    Christopher S. Potten;Catherine Booth;Gregory L. Tudor;Dawn Booth

  • The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA.

    Takao Imai;Akinori Tokunaga;Tetsu Yoshida;Mitsuhiro Hashimoto

  • Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor

    M. Matsumoto;M. Matsumoto;T. Nakagawa;T. Nakagawa;T. Inoue;E. Nagata

  • Mammalian neural stem cells

    Takuya Shimazaki;Hideyuki Okano

Frequent Co-Authors

Masaya Nakamura
Masaya Nakamura Keio University
Kazunobu Sawamoto
Kazunobu Sawamoto Nagoya City University
Yumi Matsuzaki
Yumi Matsuzaki Shimane University
Yoshiaki Toyama
Yoshiaki Toyama Keio University
Hirotaka James Okano
Hirotaka James Okano Jikei University School of Medicine
Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University
Kazuo Tsubota
Kazuo Tsubota Keio University
Yutaka Kawakami
Yutaka Kawakami International University Of Health And Welfare Atami Hospital
Shinya Yamanaka
Shinya Yamanaka Kyoto University
Minoru Narita
Minoru Narita Hoshi University

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