World's Best Scientists 2026 revealed!

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Immunology

D-Index
101
Citations
43106
World Ranking
692
National Ranking
20

Medicine

D-Index
101
Citations
43155
World Ranking
7894
National Ranking
198

Overview

Yutaka Kawakami is affiliated with Keio University in Japan and has a substantial body of research primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work encompasses multiple subfields, notably Oncology, Immunology, Molecular Biology, Cancer Research, and Genetics.

The research topics frequently addressed by Kawakami include Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, CAR-T Cell Therapy Research, Cancer, Lipids, and Metabolism, Immune Cell Function and Interaction, Gastric Cancer Management and Outcomes, and Colorectal Cancer Treatments and Studies.

Kawakami has published extensively in several key journals. The most frequent publication venues include Cancer Science with seven publications, Annals of Oncology with four, Journal of Clinical Oncology with three, and both International Journal of Molecular Sciences and BMC Cancer with two publications each.

Recent notable papers authored by or involving Kawakami cover various topics related to cancer treatment and immune regulation. These include:

  • "Multicenter Phase I/II Study of Nivolumab Combined with Paclitaxel Plus Ramucirumab as Second-line Treatment in Patients with Advanced Gastric Cancer," 2020, Clinical Cancer Research
  • "Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody," 2022, Journal for ImmunoTherapy of Cancer
  • "Enhanced anti-tumor effects of the PD-1 blockade combined with a highly absorptive form of curcumin targeting STAT3," 2020, Cancer Science
  • "AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma," 2021, The Journal of Experimental Medicine
  • "Immune-resistant mechanisms in cancer immunotherapy," 2020, International Journal of Clinical Oncology

Kawakami collaborates frequently with other researchers, including Tomonori Yaguchi, Shigeki Ohta, Takashi Iwata, Ryota Tamura, and Yukina Morimoto.

Best Publications

  • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

    Steven A. Rosenberg;James C. Yang;Douglas J. Schwartzentruber;Patrick Hwu

  • International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

    Franck Pagès;Bernhard Mlecnik;Florence Marliot;Gabriela Bindea;Gabriela Bindea;Gabriela Bindea

  • Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.

    Jérôme Galon;Jérôme Galon;Jérôme Galon;Bernhard Mlecnik;Bernhard Mlecnik;Bernhard Mlecnik;Gabriela Bindea;Gabriela Bindea;Gabriela Bindea;Helen K. Angell;Helen K. Angell;Helen K. Angell

  • Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.

    Yutaka Kawakami;Siona Eliyahu;Cynthia H. Delgado;Paul F. Robbins

  • Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

    Y Kawakami;S Eliyahu;C H Delgado;P F Robbins

  • Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.

    Yutaka Kawakami;Siona Eliyahu;Kazuyasu Sakaguchi;Paul F. Robbins

  • A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

    Takeshi Tanoue;Satoru Morita;Damian R. Plichta;Ashwin N. Skelly

  • Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells

    Chie Kudo-Saito;Hiromi Shirako;Tadashi Takeuchi;Yutaka Kawakami

  • Cancer classification using the Immunoscore: a worldwide task force

    Jérôme Galon;Franck Pagès;Francesco M Marincola;Francesco M Marincola;Helen K Angell;Helen K Angell

  • Identification of human cancers deficient in antigen processing.

    Nicholas P. Restifo;Fernando Esquivel;Yutaka Kawakami;Jonathan W. Yewdell

  • The BRAF–MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

    Hidetoshi Sumimoto;Fumie Imabayashi;Tomoko Iwata;Yutaka Kawakami

  • Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes

    A.B.H. Bakker;M.W.J. Schreurs;A.J. de Boer;Y. Kawakami

  • Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues.

    Maria R. Parkhurst;Michael L. Salgaller;Scott Southwood;Paul F. Robbins

  • RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease

    Shinji Sato;Kana Hoshino;Takashi Satoh;Tomonobu Fujita

  • Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

    Y. Kawakami;S. Eliyahu;C. Jennings;K. Sakaguchi

  • A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes.

    Paul F. Robbins;Mona El-Gamil;Yong F. Li;Yutaka Kawakami

  • Loss of Functional Beta2-Microglobulin in Metastatic Melanomas From Five Patients Receiving Immunotherapy

    Nicholas P. Restifo;Francesco M. Marincola;Yutaka Kawakami;Jeff Taubenberger

  • Human circulating CD14+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation

    Masataka Kuwana;Yuka Okazaki;Hiroaki Kodama;Keisuke Izumi

  • Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1.

    Licia Rivoltini;Yutaka Kawakami;Kazuyasu Sakaguchi;Scott Southwood

  • Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes

    Rong Fu Wang;Steven A. Rosenberg

Frequent Co-Authors

Masataka Kuwana
Masataka Kuwana Nippon Medical School
Steven A. Rosenberg
Steven A. Rosenberg National Institutes of Health
Kazuo Tsubota
Kazuo Tsubota Keio University
Yasuo Ikeda
Yasuo Ikeda Waseda University
Hideyuki Okano
Hideyuki Okano Keio University
Paul F. Robbins
Paul F. Robbins National Cancer Institute
Bernard A. FoxEarle
Bernard A. FoxEarle Earle A. Chiles Research Institute
Francesco M. Marincola
Francesco M. Marincola National Institutes of Health
Yumi Matsuzaki
Yumi Matsuzaki Shimane University

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