World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
136
Citations
62858
World Ranking
188
National Ranking
122

Medicine

D-Index
136
Citations
62866
World Ranking
1991
National Ranking
1130

Overview

Soldano Ferrone was affiliated with Harvard University in the United States. Their research primarily focused on medicine, with significant contributions in immunology and microbiology. The subfields where they published extensively included oncology, immunology, molecular biology, cancer research, and biomedical engineering.

Their scientific work concentrated on several main topics, particularly immunotherapy and immune responses, CAR-T cell therapy research, and cancer immunotherapy and biomarkers. Other notable topics included immune cell function and interaction, T-cell and B-cell immunology, cancer cells and metastasis, and extracellular vesicles in disease.

Soldano Ferrone published numerous papers in prominent venues, often collaborating with frequent co-authors such as Xinhui Wang, Cristina R. Ferrone, Giulia Cattaneo, Gianpietro Dotti, and Filippos Kontos. Their common publication venues featured:

  • Cancer Research
  • Clinical Cancer Research
  • Journal of Translational Medicine
  • Journal of the American College of Surgeons
  • Regular and Young Investigator Award Abstracts

Among their recent publications were works covering various aspects of immunotherapy and cancer research. Some of these included:

  • "B7-H3: An Attractive Target for Antibody-based Immunotherapy" (2020) published in Clinical Cancer Research
  • "Melanoma cell-derived exosomes in plasma of melanoma patients suppress functions of immune effector cells" (2020) published in Scientific Reports
  • "IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma" (2020) published in Clinical Cancer Research
  • "CAR T Cell-Based Immunotherapy for the Treatment of Glioblastoma" (2021) published in Frontiers in Neuroscience
  • "The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses" (2020) published in Immunity

Ferrone's extensive research output contributed primarily to the understanding of immune mechanisms in cancer, immunotherapy approaches, and advanced cell-based therapies such as CAR-T cells. Their work was widely cited and embedded within the broader community of translational medicine and cancer immunology.

Best Publications

  • Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance.

    Francesco M. Marincola;Elizabeth M. Jaffee;Daniel J. Hicklin;Soldano Ferrone

  • Major Histocompatibility Complex Class I-related Chain A and UL16-Binding Protein Expression on Tumor Cell Lines of Different Histotypes Analysis of Tumor Susceptibility to NKG2D-dependent Natural Killer Cell Cytotoxicity

    Daniela Pende;Paola Rivera;Stefania Marcenaro;Chien Chung Chang

  • Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer

    Scott Gettinger;Jungmin Choi;Katherine Hastings;Anna Truini

  • Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance.

    Soldano Ferrone;Francesco M. Marincola

  • Antigen-processing machinery breakdown and tumor growth.

    Barbara Seliger;Markus J Maeurer;Soldano Ferrone

  • Immunotherapy of Cancer in 2012

    John M. Kirkwood;Lisa H. Butterfield;Ahmad A. Tarhini;Hassane Zarour

  • Enhancement of sheep red blood cell human lymphocyte rosette formation by the sulfhydryl compound 2-amino ethylisothiouronium bromide.

    M.A. Pellegrino;S. Ferrone;M.P. Dierich;R.A. Reisfeld

  • HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story

    Daniel J Hicklin;Francesco M Marincola;Soldano Ferrone

  • HLA antigen changes in malignant cells: epigenetic mechanisms and biologic significance

    Michael Campoli;Soldano Ferrone

  • Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

    Marta Santisteban;Jennifer M. Reiman;Michael K. Asiedu;Marshall D. Behrens

  • Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells

    Hongwei Du;Koichi Hirabayashi;Sarah Ahn;Nancy Porterfield Kren

  • Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression.

    C. M. D'urso;Zhigang Wang;Yan Cao;R. Tatake

  • Tumor Antigen–Targeted, Monoclonal Antibody–Based Immunotherapy: Clinical Response, Cellular Immunity, and Immunoescape

    Robert L. Ferris;Elizabeth M. Jaffee;Soldano Ferrone

  • Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

    Sofia R. Gameiro;Momodou L. Jammeh;Max M. Wattenberg;Kwong Y. Tsang

  • Distribution and molecular characterization of a cell-surface and a cytoplasmic antigen detectable in human melanoma cells with monoclonal antibodies

    Barry S. Wilson;Kohzoh Imai;Pier G. Natali;Soldano Ferrone

  • NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

    Tadepally Lakshmikanth;Shannon Burke;Talib Hassan Ali;Silvia Kimpfler

  • Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation.

    Paola Contini;Massimo Ghio;Alessandro Poggi;Gilberto Filaci

  • Monoclonal antibodies for cancer immunotherapy

    Louis M Weiner;Madhav V Dhodapkar;Madhav V Dhodapkar;Soldano Ferrone

  • Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients

    Tiziano Di Tomaso;Stefania Mazzoleni;Ena Wang;Gloria Sovena

  • Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions.

    Piergiorgio Natali;Maria R. Nicotra;Renato Cavaliere;Aldo Bigotti

  • Human high molecular weight melanoma-associated antigen (HMW-MAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma

    Abraham Mittelman;Zhi Jian Chen;Hong Yang;George Y. Wong

Frequent Co-Authors

Ralph A. Reisfeld
Ralph A. Reisfeld Scripps Research Institute
Cristina R. Ferrone
Cristina R. Ferrone Harvard University
Robert L. Ferris
Robert L. Ferris University of Pittsburgh
Francesco Indiveri
Francesco Indiveri University of Genoa
Vito Quaranta
Vito Quaranta Vanderbilt University
Patrizio Giacomini
Patrizio Giacomini Sapienza University of Rome
Theresa L. Whiteside
Theresa L. Whiteside University of Pittsburgh
Pier Giorgio Natali
Pier Giorgio Natali PharmaMab S.r.l.
Gianpietro Dotti
Gianpietro Dotti University of North Carolina at Chapel Hill
Francesco M. Marincola
Francesco M. Marincola National Institutes of Health

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