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Patrizio Giacomini

Patrizio Giacomini

D-Index & Metrics

Immunology

D-Index
41
Citations
5543
World Ranking
4919
National Ranking
218

Overview

Patrizio Giacomini is affiliated with Sapienza University of Rome in Italy and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research focuses notably on cancer research, molecular biology, oncology, pulmonary and respiratory medicine, and radiology, nuclear medicine, and imaging.

Their main topics of work include:

  • Cancer Genomics and Diagnostics
  • Monoclonal and Polyclonal Antibodies Research
  • HER2/EGFR in Cancer Research
  • Advanced Biosensing Techniques and Applications
  • Advanced biosensing and bioanalysis techniques
  • Molecular Biology Techniques and Applications
  • Single-cell and spatial transcriptomics

Giacomini has published in a variety of venues, with frequent contributions to:

  • Journal of Experimental & Clinical Cancer Research
  • International Journal of Molecular Sciences
  • European Journal of Cancer
  • SSRN Electronic Journal
  • Oncology Reports

Some recent papers authored in the period 2020-2023 include:

  • Precision Medicine and Melanoma: Multi-Omics Approaches to Monitoring the Immunotherapy Response (2021), International Journal of Molecular Sciences
  • Detection of Tumor DNA in Human Plasma with a Functional PLL-Based Surface Layer and Plasmonic Biosensing (2021), ACS Sensors
  • A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery (2020), Cancers
  • Direct plasmonic detection of circulating RAS mutated DNA in colorectal cancer patients (2020), Biosensors and Bioelectronics
  • Metastatic Melanoma: Liquid Biopsy as a New Precision Medicine Approach (2023), International Journal of Molecular Sciences

Frequent co-authors collaborating with Giacomini include:

  • Matteo Allegretti
  • Elena Giordani
  • Gennaro Ciliberto
  • Alessandra Fabi
  • Edoardo Pescarmona

The combination of research topics and publication venues indicates a strong focus on cancer biology and diagnostics, employing techniques from molecular biology and biosensing to contribute to precision medicine approaches. The ongoing collaboration with multiple researchers supports a multidisciplinary approach to complex biomedical challenges.

Best Publications

  • Selective changes in expression of HLA class I polymorphic determinants in human solid tumors.

    P G Natali;M R Nicotra;A Bigotti;I Venturo

  • Modulation by recombinant DNA leukocyte (alpha) and fibroblast (beta) interferons of the expression and shedding of HLA- and tumor-associated antigens by human melanoma cells.

    P Giacomini;A Aguzzi;S Pestka;P B Fisher

  • Antibody–drug conjugates: targeting melanoma with cisplatin encapsulated in protein-cage nanoparticles based on human ferritin

    Elisabetta Falvo;Elisa Tremante;Rocco Fraioli;Carlo Leonetti

  • Antigenic heterogeneity of surgically removed primary and autologous metastatic human melanoma lesions.

    P G Natali;R Cavaliere;A Bigotti;M R Nicotra

  • Heterogeneity in the Expression of HLA and Tumor-associated Antigens by Surgically Removed and Cultured Breast Carcinoma Cells

    P. G. Natali;P. Giacomini;A. Bigotti;K. Imai

  • HLA-G, -E, -F preworkshop: tools and protocols for analysis of non-classical class I genes transcription and protein expression.

    Pascale Paul;Nathalie Rouas-Freiss;Philippe Moreau;Francisco Adrian Cabestre

  • Expression of Tumor Antigen Correlated with Metastatic Potential of Lewis Lung Carcinoma and B16 Melanoma Clones in Mice

    R. Falcioni;S. J. Kennel;P. Giacomini;G. Zupi

  • Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.

    Doriana Fruci;Patrizio Giacomini;Maria R. Nicotra;Matteo Forloni

  • Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.

    Doriana Fruci;Silvia Ferracuti;Maria Zaira Limongi;Veronica Cunsolo

  • Level of a membrane-bound high-molecular-weight melanoma-associated antigen and a cytoplasmic melanoma-associated antigen in surgically removed tissues and in sera from patients with melanoma.

    P. Giacomini;F. Veglia;P. Cordiali Fei;T. Rehle

  • NF-κB, and not MYCN, Regulates MHC Class I and Endoplasmic Reticulum Aminopeptidases in Human Neuroblastoma Cells

    Matteo Forloni;Sonia Albini;Maria Zaira Limongi;Loredana Cifaldi

  • IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma.

    Silvia Lorenzi;Matteo Forloni;Loredana Cifaldi;Chiara Antonucci

  • Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells

    Elisa Lo Monaco;Elisa Tremante;Cristina Cerboni;Elisa Melucci

  • Distinctive features of the alpha 1-domain alpha helix of HLA-C heavy chains free of beta 2-microglobulin.

    Andrea Setini;Alberto Beretta;Claudio De Santis;Raffaella Meneveri

  • Sensorineural hearing loss in rheumatoid arthritis.

    Magaro M;Zoli A;Altomonte L;Mirone L

  • Reduced L-dopa absorption and increased clinical fluctuations in Helicobacter pylori-infected Parkinson's disease patients.

    M. Pierantozzi;A. Pietroiusti;G. Sancesario;G. Lunardi

  • High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis

    Maria Benevolo;Marcella Mottolese;Elisa Tremante;Francesca Rollo

  • Natural Killer Cells Efficiently Reject Lymphoma Silenced for the Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing

    Loredana Cifaldi;Elisa Lo Monaco;Matteo Forloni;Ezio Giorda

  • Immunochemical analysis of the modulation of human melanoma-associated antigens by DNA recombinant immune interferon

    P Giacomini;L Imberti;A Aguzzi;P B Fisher

  • Regulation of class II MHC gene expression by interferons: insights into the mechanism of action of interferon (review).

    Giacomini P;Fisher Pb;Duigou Gj;Gambari R

  • Analysis of the interaction between a human high molecular weight melanoma-associated antigen and the monoclonal antibodies to three distinct antigenic determinants.

    P Giacomini;P Natali;S Ferrone

  • Double Determinant Immunoassay to Measure a Human High-molecular-weight Melanoma-associated Antigen

    Patrizio Giacomini;Ah Kau Ng;Raphe R. S. Kantor;Pier Giorgio Natali

Frequent Co-Authors

Pier Giorgio Natali
Pier Giorgio Natali PharmaMab S.r.l.
Roberto Gambari
Roberto Gambari University of Ferrara
Soldano Ferrone
Soldano Ferrone Harvard University
Claudio Nastruzzi
Claudio Nastruzzi University of Ferrara
Paolo Stanzione
Paolo Stanzione University of Rome Tor Vergata
Paul B. Fisher
Paul B. Fisher Virginia Commonwealth University
Marcella Mottolese
Marcella Mottolese IRCCS Regina Elena Institute
Mariangela Pierantozzi
Mariangela Pierantozzi University of Rome Tor Vergata
Nicoletta Bianchi
Nicoletta Bianchi University of Ferrara
Maria Grazia Marciani
Maria Grazia Marciani University of Rome Tor Vergata

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