2026 Nathalie Rouas-Freiss: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	71	2320	2134	90	82	155	17958

Overview

Nathalie Rouas-Freiss is affiliated with the French Alternative Energies and Atomic Energy Commission (CEA) in France. Their research focuses primarily on immunology and medicine, particularly in the areas of reproductive system and pregnancy, immunotherapy, and immune responses.

Their recent publications contribute to several key topics, including skin immunity, immune checkpoints during pregnancy, post-ischemic angiogenesis, preeclampsia, and tumor immunology. Notable papers include:

Skin Immunity and Tolerance: Focus on Epidermal Keratinocytes Expressing HLA-G, 2021, Frontiers in Immunology
Role of the HLA-G immune checkpoint molecule in pregnancy, 2021, Human Immunology
Cord blood-endothelial colony forming cells are immunotolerated and participate at post-ischemic angiogenesis in an original dorsal chamber immunocompetent mouse model, 2020, Stem Cell Research & Therapy
Immunologic aspects of preeclampsia, 2024, AJOG Global Reports
Tumor infiltrating and peripheral CD4+ILT2+ T cells are a cytotoxic subset selectively inhibited by HLA-G in clear cell renal cell carcinoma patients, 2021, Cancer Letters

The scientist has collaborated frequently with several co-authors, including:

Edgardo D. Carosella
Joël LeMaoult
Guillaume Mestrallet
Philippe Moreau
Chantal Schenowitz

Their work is published often in journals such as:

Frontiers in Immunology
Human Immunology
AJOG Global Reports
Stem Cell Research & Therapy
Cancer Letters

Main fields of study include Medicine and Immunology and Microbiology, with specific subfields focused on Immunology, Public Health, Environmental and Occupational Health, Obstetrics and Gynecology, Reproductive Medicine, and Genetics.

Key research topics connected to this scientist cover:

Reproductive System and Pregnancy
Endometriosis Research and Treatment
Immunotherapy and Immune Responses
Wound Healing and Treatments
Ectopic Pregnancy Diagnosis and Management
Mesenchymal stem cell research
Immune Cell Function and Interaction

Best Publications

Human Leukocyte Antigen‐G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+ Regulatory T Cells

Zohair Selmani;Abderrahim Naji;Ines Zidi;Benoit Favier

1464
Citations
Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis

Nathalie Rouas-Freiss;Rachel Marchal-Bras Gonçalves;Catherine Menier;Jean Dausset

1008
Citations
Biological functions of mesenchymal stem cells and clinical implications

Abderrahim Naji;Masamitsu Eitoku;Benoit Favier;Frédéric Deschaseaux

658
Citations
HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance

P Paul;N Rouas-Freiss;I Khalil-Daher;P Moreau

612
Citations
The alpha1 domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells: is HLA-G the public ligand for natural killer cell inhibitory receptors?

Nathalie Rouas-Freiss;Rachel E. Marchal;Marek Kirszenbaum;Jean Dausset

537
Citations
HLA-G: from biology to clinical benefits

Edgardo D. Carosella;Philippe Moreau;Joël LeMaoult;Nathalie Rouas-Freiss

499
Citations
HLA-G molecules: from maternal-fetal tolerance to tissue acceptance.

Edgardo D Carosella;Philippe Moreau;Joël Le Maoult;Magali Le Discorde

485
Citations
HLA-G2, -G3, and -G4 Isoforms Expressed as Nonmature Cell Surface Glycoproteins Inhibit NK and Antigen-Specific CTL Cytolysis

Béatrice Riteau;Nathalie Rouas-Freiss;Catherine Menier;Pascale Paul

484
Citations
Soluble HLA-G protein secreted by allo-specific CD4+ T cells suppresses the allo-proliferative response: A CD4+ T cell regulatory mechanism

Nermine Lila;Nathalie Rouas-Freiss;Jean Dausset;Alain Carpentier

467
Citations
HLA-G: An Immune Checkpoint Molecule.

Edgardo D Carosella;Nathalie Rouas-Freiss;Diana Tronik-Le Roux;Philippe Moreau

457
Citations
Beyond the increasing complexity of the immunomodulatory HLA-G molecule.

Edgardo D. Carosella;Benoit Favier;Nathalie Rouas-Freiss;Philippe Moreau

441
Citations
HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes.

Frédérique-Anne Le Gal;Béatrice Riteau;Christine Sedlik;Iman Khalil-Daher

429
Citations
HLA-G proteins in cancer: do they provide tumor cells with an escape mechanism?

Nathalie Rouas-Freiss;Philippe Moreau;Soldano Ferrone;Edgardo D. Carosella

347
Citations
HLA-G : a shield against inflammatory aggression

Edgardo D Carosella;Philippe Moreau;Selim Aractingi;Nathalie Rouas-Freiss

264
Citations
HLA-G inhibits the allogeneic proliferative response

Beatrice Riteau;Catherine Menier;Iman Khalil-Daher;Christine Sedlik

261
Citations
Evidence to support the role of HLA-G5 in allograft acceptance through induction of immunosuppressive/ regulatory T cells

Solène Le Rond;Christine Azéma;Irène Krawice-Radanne;Antoine Durrbach

251
Citations
HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition

Béatrice Riteau;Catherine Menier;Iman Khalil-Daher;Silvia Martinozzi

240
Citations
NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: immaturity of NK cells and inhibitory effect of NKG2A override GvL effect

Stephanie Nguyen;Nathalie Dhedin;Jean-Paul Vernant;Mathieu Kuentz

236
Citations
Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation.

Caroline Créput;Antoine Durrbach;Catherine Menier;Catherine Guettier

230
Citations
Monocytes and T lymphocytes in HIV-1-positive patients express HLA-G molecule.

José M. Lozano;Rafael Gonzalez;José M. Kindelan;Nathalie Rouas-Freiss

224
Citations

Frequent Co-Authors

Edgardo D. Carosella Université Paris Cité

Jean Dausset Grenoble Alpes University

Joel LeMaoult Université Paris Cité

Philippe Moreau University of Nantes

Pascale Paul Aix-Marseille University

Eduardo Antônio Donadi Universidade de São Paulo

Luc Sensebé StromaLab

Dominique Bellet Institute Curie

Vera Rebmann Essen University Hospital

Jean-Gérard Guillet Grenoble Alpes University

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