D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Immunology
Italy
2022

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 134 Citations 61,665 511 World Ranking 65 National Ranking 3
Medicine D-index 135 Citations 62,688 541 World Ranking 820 National Ranking 19
Best Scientists D-index 161 Citations 93,230 707 World Ranking 814 National Ranking 15

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

2022 - Research.com Immunology in Italy Leader Award

1991 - Member of Academia Europaea

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cancer

His primary areas of study are Immunology, Cell biology, Interleukin 21, Receptor and Lymphokine-activated killer cell. His work carried out in the field of Immunology brings together such families of science as Natural killer cell and Transplantation. He has researched Cell biology in several fields, including NKG2D, Nectin and Cytokine.

His Interleukin 21 research includes themes of IL-2 receptor, Antigen-presenting cell, Natural killer T cell, CD16 and Interleukin 12. The Receptor study combines topics in areas such as Molecular biology, Natural Cytotoxicity Triggering Receptor 1, Major histocompatibility complex and Cytotoxicity. His Lymphokine-activated killer cell research includes elements of Stromal cell, Janus kinase 3, Myeloid-derived Suppressor Cell, NK-92 and Innate lymphoid cell.

His most cited work include:

  • Mesenchymal stem cells in health and disease (2397 citations)
  • Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis (1532 citations)
  • Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG. (999 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Immunology, Cell biology, Receptor, Interleukin 21 and Molecular biology. His study in Immunology is interdisciplinary in nature, drawing from both Natural killer cell, Cytotoxic T cell and Transplantation. His Cell biology research is multidisciplinary, relying on both NKG2D, Cellular differentiation, MHC class I and Innate lymphoid cell.

His research in Receptor tackles topics such as Cell which are related to areas like Cancer research. His work deals with themes such as Innate immune system, Interleukin 12 and Antigen-presenting cell, which intersect with Interleukin 21. His Lymphokine-activated killer cell study combines topics from a wide range of disciplines, such as NK-92 and Natural killer T cell.

He most often published in these fields:

  • Immunology (57.44%)
  • Cell biology (41.66%)
  • Receptor (37.90%)

What were the highlights of his more recent work (between 2013-2021)?

  • Immunology (57.44%)
  • Immune system (16.30%)
  • Cancer research (12.03%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Immunology, Immune system, Cancer research, Cell biology and Innate lymphoid cell. His research integrates issues of Interleukin 12, Receptor and Hematopoietic stem cell transplantation in his study of Immunology. His Immune system research is multidisciplinary, incorporating perspectives in Stromal cell, Haematopoiesis and Virology.

Lorenzo Moretta has included themes like Cell, Cell culture, Downregulation and upregulation and Immunotherapy in his Cancer research study. His Cell biology study integrates concerns from other disciplines, such as Chemokine and Cellular differentiation. His Human leukocyte antigen research incorporates elements of Natural killer cell and CD19.

Between 2013 and 2021, his most popular works were:

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (301 citations)
  • HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders (282 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cancer

The scientist’s investigation covers issues in Immunology, Immune system, Cell biology, Receptor and Interleukin 12. His study in Lymphokine-activated killer cell, Interleukin 21, Innate lymphoid cell and NK-92 falls under the purview of Immunology. His Immune system study combines topics in areas such as Cell, Cancer research and Monoclonal antibody.

In general Cell biology study, his work on Progenitor cell often relates to the realm of Decidua, thereby connecting several areas of interest. His Receptor study incorporates themes from Virus, Viral entry, Metastasis, Tertiary Lymphoid Structures and Cytotoxicity. His work in Interleukin 12 addresses issues such as Tumor necrosis factor alpha, which are connected to fields such as CD49b and Eomesodermin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mesenchymal stem cells in health and disease

Antonio Uccelli;Lorenzo Moretta;Vito Pistoia.
Nature Reviews Immunology (2008)

3417 Citations

Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (2001)

1937 Citations

Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG.

L Moretta;S R Webb;C E Grossi;P M Lydyard.
Journal of Experimental Medicine (1977)

1492 Citations

Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation

Grazia Maria Spaggiari;Andrea Capobianco;Stelvio Becchetti;Maria Cristina Mingari.
Blood (2006)

1104 Citations

Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells.

Guido Ferlazzo;Ming L. Tsang;Lorenzo Moretta;Lorenzo Moretta;Giovanni Melioli.
Journal of Experimental Medicine (2002)

1103 Citations

Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2.

Grazia Maria Spaggiari;Andrea Capobianco;Heba Abdelrazik;Flavio Becchetti.
Blood (2008)

1077 Citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (1996)

935 Citations

Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells

Daniela Pende;Silvia Parolini;Anna Pessino;Simona Sivori.
Journal of Experimental Medicine (1999)

870 Citations

NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

Massimo Vitale;Cristina Bottino;Simona Sivori;Lorenza Sanseverino.
Journal of Experimental Medicine (1998)

827 Citations

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

Cristina Bottino;Roberta Castriconi;Daniela Pende;Paola Rivera.
Journal of Experimental Medicine (2003)

808 Citations

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