World's Best Scientists 2026 revealed!
Cristina Bottino

Cristina Bottino

D-Index & Metrics

Immunology

D-Index
88
Citations
32997
World Ranking
1152
National Ranking
42

Cristina Bottino publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Cristina Bottino sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 216 publications — 40th percentile

40% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Cristina Bottino D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Cristina Bottino sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 88 D-Index — 77th percentile

77% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Cristina Bottino is affiliated with the University of Genoa in Italy and works primarily in the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Their research spans various subfields including Immunology, Oncology, Molecular Biology, Biomedical Engineering, and Cancer Research.

The scientist's work covers a range of main topics, notably Immune Cell Function and Interaction, pathways involving IL-33, ST2, and ILC, Immune Cells in Cancer, Neuroblastoma Research and Treatments, CAR-T Cell Therapy Research, 3D Printing in Biomedical Research, and the role of MicroRNA in disease regulation.

Frequent publication venues associated with Cristina Bottino include Frontiers in Immunology, Cancers, OncoImmunology, Frontiers in Bioengineering and Biotechnology, and the Journal for ImmunoTherapy of Cancer.

They have collaborated extensively with several coauthors, including Roberta Castriconi, Alessandra Dondero, Chiara Vitale, Martina Serra, and Martina Morini.

Notable recent papers authored or coauthored by Cristina Bottino include:

  • NK Cell Function Regulation by TGF-β-Induced Epigenetic Mechanisms, 2020, Frontiers in Immunology
  • A multi-organ-on-chip to recapitulate the infiltration and the cytotoxic activity of circulating NK cells in 3D matrix-based tumor model, 2022, Frontiers in Bioengineering and Biotechnology
  • Tumor Microenvironment and Hydrogel-Based 3D Cancer Models for In Vitro Testing Immunotherapies, 2022, Cancers
  • Multiparametric flow cytometry highlights B7-H3 as a novel diagnostic/therapeutic target in GD2neg/low neuroblastoma variants, 2021, Journal for ImmunoTherapy of Cancer
  • Monocyte and Macrophage in Neuroblastoma: Blocking Their Pro-Tumoral Functions and Strengthening Their Crosstalk with Natural Killer Cells, 2023, Cells

Best Publications

  • Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.

    Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende

  • Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

    Cristina Bottino;Roberta Castriconi;Daniela Pende;Paola Rivera

  • RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

    Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende

  • Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells

    Daniela Pende;Silvia Parolini;Anna Pessino;Simona Sivori

  • NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

    Massimo Vitale;Cristina Bottino;Simona Sivori;Lorenza Sanseverino

  • Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells

    Roberta Castriconi;Claudia Cantoni;Mariella Della Chiesa;Massimo Vitale

  • P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

    Alessandro Moretta;Massimo Vitale;Cristina Bottino;Anna Maria Orengo

  • Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity.

    Anna Pessino;Simona Sivori;Cristina Bottino;Angela Malaspina

  • Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

    Nicolai Wagtmann;Roberto Biassoni;Claudia Cantoni;Simonetta Verdiani

  • X-Linked Lymphoproliferative Disease 2b4 Molecules Displaying Inhibitory Rather than Activating Function Are Responsible for the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected Cells

    Silvia Parolini;Cristina Bottino;Michela Falco;Raffaella Augugliaro

  • p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation

    Simona Sivori;Massimo Vitale;Luigia Morelli;Lorenza Sanseverino

  • NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells

    Simona Sivori;Daniela Pende;Cristina Bottino;Emanuela Marcenaro

  • Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

    A Moretta;C Bottino;D Pende;G Tripodi

  • NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily.

    Claudia Cantoni;Cristina Bottino;Massimo Vitale;Anna Pessino

  • Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

    Alessandro Moretta;Simona Sivori;Massimo Vitale;Daniela Pende

  • The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

    D Pende;R Biassoni;C Cantoni;S Verdiani

  • The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

    Roberto Biassoni;Claudia Cantoni;Michela Falco;Simonetta Verdiani

  • What is a natural killer cell

    Alessandro Moretta;Cristina Bottino;Maria Cristina Mingari;Roberto Biassoni

  • Natural killer cells in HIV-1 infection: Dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates

    Domenico Mavilio;Janet Benjamin;Marybeth Daucher;Gabriella Lombardo

  • Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis.

    Alessandro Moretta;R. Biassoni;Cristina Bottino;Maria Cristina Mingari

Frequent Co-Authors

Alessandro Moretta
Alessandro Moretta University of Genoa
Lorenzo Moretta
Lorenzo Moretta Bambino Gesù Children's Hospital
Roberto Biassoni
Roberto Biassoni Istituto Giannina Gaslini
Daniela Pende
Daniela Pende University of Genoa
Claudia Cantoni
Claudia Cantoni University of Genoa
Maria Cristina Mingari
Maria Cristina Mingari University of Genoa
Massimo Vitale
Massimo Vitale University of Genoa
Simona Sivori
Simona Sivori University of Genoa
Michela Falco
Michela Falco Istituto Giannina Gaslini
Ermanno Ciccone
Ermanno Ciccone University of Genoa

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