D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 63 Citations 18,256 139 World Ranking 1478 National Ranking 52

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • Antibody

Her primary areas of study are Receptor, Molecular biology, Cell biology, Natural killer cell and Immunology. The various areas that she examines in her Receptor study include NKG2D, Cancer research, Signal transduction and Major histocompatibility complex. Her Molecular biology research is multidisciplinary, incorporating elements of Cell culture, Antigen, NK Cell Lectin-Like Receptor Subfamily D, CD94/NKG2 and Antibody.

Her Cell biology research is multidisciplinary, relying on both Interleukin 12, Interleukin 21, Natural Cytotoxicity Triggering Receptor 1, Lymphokine-activated killer cell and Cytotoxicity. The Natural killer cell study which covers Human leukocyte antigen that intersects with Transmembrane protein and Downregulation and upregulation. Her study in the fields of Immune system, Tumor necrosis factor alpha and Lymphocyte activation under the domain of Immunology overlaps with other disciplines such as Virus diseases.

Her most cited work include:

  • Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis (1532 citations)
  • RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS (768 citations)
  • Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells (687 citations)

What are the main themes of her work throughout her whole career to date?

Cristina Bottino mainly investigates Receptor, Cell biology, Immunology, Molecular biology and Interleukin 21. Her Receptor study incorporates themes from Natural killer cell, Cell, Human leukocyte antigen and NKG2D. Her study looks at the relationship between Cell biology and topics such as Natural Cytotoxicity Triggering Receptor 1, which overlap with Natural Cytotoxicity Triggering Receptor 3.

Her study explores the link between Immunology and topics such as Cancer research that cross with problems in Neuroblastoma. The Molecular biology study combines topics in areas such as T cell, CD3, CD8, Antigen and Monoclonal antibody. Her studies deal with areas such as Interleukin 12 and Signal transduction as well as Interleukin 21.

She most often published in these fields:

  • Receptor (54.29%)
  • Cell biology (54.29%)
  • Immunology (48.10%)

What were the highlights of her more recent work (between 2013-2021)?

  • Immunology (48.10%)
  • Cell biology (54.29%)
  • Cell (21.90%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Immunology, Cell biology, Cell, Immune system and Receptor. Her study in Immunology is interdisciplinary in nature, drawing from both Cytotoxic T cell and Interleukin 12. Her Cell biology research incorporates themes from microRNA, Chemokine receptor, Cytokine and Macrophage polarization.

Her Cell study combines topics in areas such as Growth factor, Cytotoxicity, Tumor progression, Extracellular matrix and Interleukin 15. She has included themes like Mesenchymal stem cell, Neuroblastoma and Imatinib mesylate in her Immune system study. She does research in Receptor, focusing on Platelet-derived growth factor receptor specifically.

Between 2013 and 2021, her most popular works were:

  • Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses. (88 citations)
  • PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance (57 citations)
  • TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells. (55 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cancer

The scientist’s investigation covers issues in Immunology, Immune system, Chemokine receptor, Cell and Cell biology. Her Immunology study integrates concerns from other disciplines, such as Cancer research and Neuroblastoma. Her Cell research integrates issues from Receptor and Cytotoxicity.

Her work carried out in the field of Receptor brings together such families of science as Extracellular, Extracellular matrix and Cytokine. Her Cell biology study combines topics from a wide range of disciplines, such as Interleukin, IL-2 receptor and Cellular differentiation. Her studies in Interleukin 21 integrate themes in fields like Tumor microenvironment and Interleukin 12.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (2001)

1937 Citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (1996)

935 Citations

Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells

Daniela Pende;Silvia Parolini;Anna Pessino;Simona Sivori.
Journal of Experimental Medicine (1999)

870 Citations

NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

Massimo Vitale;Cristina Bottino;Simona Sivori;Lorenza Sanseverino.
Journal of Experimental Medicine (1998)

827 Citations

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

Cristina Bottino;Roberta Castriconi;Daniela Pende;Paola Rivera.
Journal of Experimental Medicine (2003)

808 Citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

Alessandro Moretta;Massimo Vitale;Cristina Bottino;Anna Maria Orengo.
Journal of Experimental Medicine (1993)

772 Citations

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

Nicolai Wagtmann;Roberto Biassoni;Claudia Cantoni;Simonetta Verdiani.
Immunity (1995)

680 Citations

X-Linked Lymphoproliferative Disease 2b4 Molecules Displaying Inhibitory Rather than Activating Function Are Responsible for the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected Cells

Silvia Parolini;Cristina Bottino;Michela Falco;Raffaella Augugliaro.
Journal of Experimental Medicine (2000)

677 Citations

Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity.

Anna Pessino;Simona Sivori;Cristina Bottino;Angela Malaspina.
Journal of Experimental Medicine (1998)

637 Citations

Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells

Roberta Castriconi;Claudia Cantoni;Mariella Della Chiesa;Massimo Vitale.
Proceedings of the National Academy of Sciences of the United States of America (2003)

588 Citations

Best Scientists Citing Cristina Bottino

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Alessandro Moretta

Alessandro Moretta

University of Genoa

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Eric Vivier

Eric Vivier

Aix-Marseille University

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Maria Cristina Mingari

Maria Cristina Mingari

University of Genoa

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Ofer Mandelboim

Ofer Mandelboim

Hebrew University of Jerusalem

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Lewis L. Lanier

Lewis L. Lanier

University of California, San Francisco

Publications: 108

Armand Bensussan

Armand Bensussan

Inserm : Institut national de la santé et de la recherche médicale

Publications: 105

Peter Parham

Peter Parham

Stanford University

Publications: 93

Marco Colonna

Marco Colonna

Washington University in St. Louis

Publications: 83

Mark J. Smyth

Mark J. Smyth

QIMR Berghofer Medical Research Institute

Publications: 81

Daniela Pende

Daniela Pende

University of Genoa

Publications: 78

Claudia Cantoni

Claudia Cantoni

University of Genoa

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David H. Raulet

David H. Raulet

University of California, Berkeley

Publications: 72

Miguel López-Botet

Miguel López-Botet

Pompeu Fabra University

Publications: 70

Eric O. Long

Eric O. Long

National Institutes of Health

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Karl-Johan Malmberg

Karl-Johan Malmberg

Oslo University Hospital

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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