Cristina Bottino

Overview

Best Publications

• Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.

  Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende

  2221
  Citations

• Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

  Cristina Bottino;Roberta Castriconi;Daniela Pende;Paola Rivera

  1065
  Citations

• RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

  Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende

  1064
  Citations

• Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells

  Daniela Pende;Silvia Parolini;Anna Pessino;Simona Sivori

  1021
  Citations

• NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

  Massimo Vitale;Cristina Bottino;Simona Sivori;Lorenza Sanseverino

  953
  Citations

• Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells

  Roberta Castriconi;Claudia Cantoni;Mariella Della Chiesa;Massimo Vitale

  842
  Citations

• P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

  Alessandro Moretta;Massimo Vitale;Cristina Bottino;Anna Maria Orengo

  809
  Citations

• Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity.

  Anna Pessino;Simona Sivori;Cristina Bottino;Angela Malaspina

  727
  Citations

• Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

  Nicolai Wagtmann;Roberto Biassoni;Claudia Cantoni;Simonetta Verdiani

  722
  Citations

• X-Linked Lymphoproliferative Disease 2b4 Molecules Displaying Inhibitory Rather than Activating Function Are Responsible for the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected Cells

  Silvia Parolini;Cristina Bottino;Michela Falco;Raffaella Augugliaro

  702
  Citations

• p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation

  Simona Sivori;Massimo Vitale;Luigia Morelli;Lorenza Sanseverino

  683
  Citations

• NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells

  Simona Sivori;Daniela Pende;Cristina Bottino;Emanuela Marcenaro

  619
  Citations

• Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

  A Moretta;C Bottino;D Pende;G Tripodi

  575
  Citations

• NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily.

  Claudia Cantoni;Cristina Bottino;Massimo Vitale;Anna Pessino

  556
  Citations

• Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

  Alessandro Moretta;Simona Sivori;Massimo Vitale;Daniela Pende

  556
  Citations

• The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

  D Pende;R Biassoni;C Cantoni;S Verdiani

  551
  Citations

• The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

  Roberto Biassoni;Claudia Cantoni;Michela Falco;Simonetta Verdiani

  491
  Citations

• What is a natural killer cell

  Alessandro Moretta;Cristina Bottino;Maria Cristina Mingari;Roberto Biassoni

  481
  Citations

• Natural killer cells in HIV-1 infection: Dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates

  Domenico Mavilio;Janet Benjamin;Marybeth Daucher;Gabriella Lombardo

  481
  Citations

• Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis.

  Alessandro Moretta;R. Biassoni;Cristina Bottino;Maria Cristina Mingari

  478
  Citations