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Ermanno Ciccone

Ermanno Ciccone

D-Index & Metrics

Immunology

D-Index
43
Citations
7864
World Ranking
4838
National Ranking
213

Overview

Ermanno Ciccone is affiliated with the University of Genoa in Italy. Their research broadly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several specialized subfields. These subfields include Molecular Biology, Genetics, Pharmacology, Oncology, and Cardiology and Cardiovascular Medicine.

Their scientific contributions are distributed across key topics such as Chronic Lymphocytic Leukemia Research, Berberine and alkaloids research, Cancer-related Molecular Pathways, RNA Research and Splicing, Ubiquitin and proteasome pathways, as well as Cardiomyopathy and Myosin Studies.

Recent works by Ciccone include studies published in prominent venues. Notable publications are:

  • Berberine affects mitochondrial activity and cell growth of leukemic cells from chronic lymphocytic leukemia patients, 2020, Scientific Reports
  • SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line, 2021, BMC Molecular and Cell Biology

Within their research community, Ciccone has frequently collaborated with several co-authors, including Fabio Ghiotto, Andrea Nicola Mazzarello, Franco Fais, Silvia Bruno, and Silvia Ravera. These collaborations reflect ongoing partnerships in advancing studies related to their core scientific interests.

Their publications have appeared primarily in journals such as Scientific Reports and BMC Molecular and Cell Biology, indicating a dissemination of findings within molecular and cellular biology research outlets.

Best Publications

  • P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

    Alessandro Moretta;Massimo Vitale;Cristina Bottino;Anna Maria Orengo

  • Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

    A Moretta;C Bottino;D Pende;G Tripodi

  • Peptide Specificity in the Recognition of MHC Class I by Natural Killer Cell Clones

    Mauro S. Malnati;Marta Peruzzi;Kenneth C. Parker;William E. Biddison

  • A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

    Alessandro Moretta;Giuseppe Tambussi;Cristina Bottino;Gino Tripodi

  • CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.

    A Moretta;A Poggi;D Pende;G Tripodi

  • Human Natural Killer Cells: Origin, Clonality, Specificity, and Receptors

    Lorenzo Moretta;Ermanno Ciccone;Maria Cristina Mingari;Roberto Biassoni

  • Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).

    E Ciccone;D Pende;O Viale;A Than

  • Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues.

    B Falini;L Flenghi;S Pileri;P Pelicci

  • Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.

    E Ciccone;D Pende;O Viale;C Di Donato

  • Allorecognition by NK cells: nonself or no self?

    Lorenzo Moretta;Ermanno Ciccone;Alessandro Moretta;Petter Höglund

  • Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

    Alessandro Moretta;Massimo Vitale;Simona Sivori;Cristina Bottino

  • Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.

    Cristina Bottino;Giuseppe Tambussi;Silvano Ferrini;Ermanno Ciccone

  • Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene

    Marco Colonna;Thomas Spies;Jack L. Strominger;Ermanno Ciccone

  • Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes.

    Y Takihara;J Reimann;E Michalopoulos;E Ciccone

  • The CD85/LIR-1/ILT2 inhibitory receptor is expressed by all human T lymphocytes and down-regulates their functions.

    Daniele Saverino;Marina Fabbi;Fabio Ghiotto;Andrea Merlo

  • Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.

    E Ciccone;O Viale;D Pende;M Malnati

  • Selective Increase of a Subset of T Cell Receptor γδ T Lymphocytes in the Peripheral Blood of Patients with Human Immunodeficiency Virus Type 1 Infection

    A. De Maria;A. Ferrazin;S. Ferrini;E. Ciccone

  • In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors.

    Maria Cristina Mingari;Alessandro Poggi;Roberto Biassoni;Rosanna Bellomo

  • Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.

    Ermanno Ciccone;Daniela Pende;Oriane Viale;Giuseppe Tambussi

  • Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements

    Mauro S. Malnati;Paolo Lusso;Ermanno Ciccone;Alessandro Moretta

  • A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).

    E Ciccone;S Ferrini;C Bottino;O Viale

  • Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells

    Ermanno Ciccone;Daniela Pende;Massimo Vitale;Luca Nanni

  • ANTIGEN RECOGNITION BY HUMAN T CELL RECEPTOR y-POSITIVE LYMPHOCYTES Specific Lysis of Allogeneic Mixed Lymphocyte Culture BriefDefinitiveReport

    Ermanno Ciccone;Oriane Viale;Cristina Bottino;Daniela Pende

Frequent Co-Authors

Alessandro Moretta
Alessandro Moretta University of Genoa
Lorenzo Moretta
Lorenzo Moretta Bambino Gesù Children's Hospital
Carlo E. Grossi
Carlo E. Grossi University of Genoa
Daniela Pende
Daniela Pende University of Genoa
Cristina Bottino
Cristina Bottino University of Genoa
Silvano Ferrini
Silvano Ferrini University of Genoa
Giuseppe Tambussi
Giuseppe Tambussi Vita-Salute San Raffaele University
Maria Cristina Mingari
Maria Cristina Mingari University of Genoa
Roberto Biassoni
Roberto Biassoni Istituto Giannina Gaslini
Massimo Vitale
Massimo Vitale University of Genoa

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