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Microbiology

D-Index
66
Citations
14468
World Ranking
2416
National Ranking
58

Overview

Alessandro Poggi is affiliated with the University of Modena and Reggio Emilia in Italy and conducts research primarily in the fields of Medicine and Immunology and Microbiology. Their work focuses on key subfields including Oncology, Immunology, Molecular Biology, Biomedical Engineering, and Infectious Diseases.

Research topics prominently associated with Poggi involve:

  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Cancer Cells and Metastasis
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • T-cell and B-cell Immunology

Poggi has contributed to numerous academic papers across respected scientific journals. Noteworthy recent publications include:

  • "Natural killer cells and immune-checkpoint inhibitor therapy: Current knowledge and new challenges," 2021, Molecular Therapy - Oncolytics
  • "The Ovarian Cancer Tumor Immune Microenvironment (TIME) as Target for Therapy: A Focus on Innate Immunity Cells as Therapeutic Effectors," 2020, International Journal of Molecular Sciences
  • "A multi-organ-on-chip to recapitulate the infiltration and the cytotoxic activity of circulating NK cells in 3D matrix-based tumor model," 2022, Frontiers in Bioengineering and Biotechnology
  • "Physical Characterization of Colorectal Cancer Spheroids and Evaluation of NK Cell Infiltration Through a Flow-Based Analysis," 2020, Frontiers in Immunology
  • "Cancer Nanomedicine Special Issue Review Anticancer Drug Delivery with Nanoparticles: Extracellular Vesicles or Synthetic Nanobeads as Therapeutic Tools for Conventional Treatment or Immunotherapy," 2020, Cancers

Frequent collaborators in Poggi's research endeavors include Roberto Benelli, Maria Raffaella Zocchi, Delfina Costa, Serena Matis, and Francesca Tosetti.

The scientist publishes regularly in journals such as:

  • Cancers
  • Cells
  • International Journal of Molecular Sciences
  • Frontiers in Immunology
  • PubMed

Best Publications

  • Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes

    Cristina Andrei;Paola Margiocco;Alessandro Poggi;Lavinia V. Lotti

  • The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

    Roberto Biassoni;Claudia Cantoni;Michela Falco;Simonetta Verdiani

  • Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction

    Claudia Prevosto;Marta Zancolli;Paolo Canevali;Maria Raffaella Zocchi

  • NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1.

    Claudia Semino;Giovanna Angelini;Alessandro Poggi;Anna Rubartelli

  • Major histocompatibility complex class I‐specific receptors on human natural killer and T lymphocytes

    Alessandro Moretta;Roberto Biassoni;Cristina Bottino;Daniela Pende

  • Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation.

    Paola Contini;Massimo Ghio;Alessandro Poggi;Gilberto Filaci

  • The selective engulfment of apoptotic bodies by dendritic cells is mediated by the αvβ3 integrin and requires intracellular and extracellular calcium

    Anna Rubartelli;Alessandro Poggi;M. Raffaella Zocchi

  • Extracellular DNA in biofilms.

    Lucio Montanaro;Alessandro Poggi;Livia Visai;Stefano Ravaioli

  • Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production

    Maria Cristina Mingari;Chiara Vitale;Anna Cambiaggi;Francesca Schiavetti

  • Antibiofilm activity of a monolayer of silver nanoparticles anchored to an amino-silanized glass surface

    Angelo Taglietti;Carla Renata Arciola;Agnese D'Agostino;Giacomo Dacarro

  • Comparative Analysis of DNA Repair in Stem and Nonstem Glioma Cell Cultures

    Monica Ropolo;Antonio Daga;Fabrizio Griffero;Mara Foresta

  • Vδ1 T lymphocytes producing IFN-γ and IL-17 are expanded in HIV-1–infected patients and respond to Candida albicans

    Daniela Fenoglio;Alessandro Poggi;Silvia Catellani;Florinda Battaglia

  • Vδ1 T Lymphocytes from B-CLL Patients Recognize ULBP3 Expressed on Leukemic B Cells and Up-Regulated by Trans-Retinoic Acid

    Alessandro Poggi;Claudia Venturino;Silvia Catellani;Marino Clavio

  • Human γδ T cells: a nonredundant system in the immune-surveillance against cancer

    Marina Ferrarini;Elisabetta Ferrero;Lorenzo Dagna;Alessandro Poggi

  • Catastrophic NAD + Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

    Santina Bruzzone;Floriana Fruscione;Sara Morando;Tiziana Ferrando

  • Interaction between Human NK Cells and Bone Marrow Stromal Cells Induces NK Cell Triggering: Role of NKp30 and NKG2D Receptors

    Alessandro Poggi;Claudia Prevosto;Anna Maria Massaro;Simone Negrini

  • The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.

    Inga Bauer;Alessia Grozio;Denise Lasigliè;Giovanna Basile

  • NK cell-mediated lysis of autologous antigen-presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the natural cytotoxicity receptors NKp30 and NKp46.

    Grazia Maria Spaggiari;Roberta Carosio;Daniela Pende;Stefania Marcenaro

  • The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-α production

    Stefania Laurent;Paola Queirolo;Silvia Boero;Sandra Salvi

  • Migration of Vδ1 and Vδ2 T cells in response to CXCR3 and CXCR4 ligands in healthy donors and HIV-1-infected patients: Competition by HIV-1 Tat

    Alessandro Poggi;Roberta Carosio;Daniela Fenoglio;Sabrina Brenci

  • Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE.

    Santina Bruzzone;Floriana Fruscione;Sara Morando;Alessandro Poggi

Frequent Co-Authors

Maria Raffaella Zocchi
Maria Raffaella Zocchi Vita-Salute San Raffaele University
Lorenzo Moretta
Lorenzo Moretta Bambino Gesù Children's Hospital
Maria Cristina Mingari
Maria Cristina Mingari University of Genoa
Roberto Benelli
Roberto Benelli University of Genoa
Alessandro Moretta
Alessandro Moretta University of Genoa
Anna Rubartelli
Anna Rubartelli National Cancer Research Institute, UK
Roberto Biassoni
Roberto Biassoni Istituto Giannina Gaslini
Alessio Nencioni
Alessio Nencioni University of Genoa
Fabrizio Montecucco
Fabrizio Montecucco University of Genoa
Santina Bruzzone
Santina Bruzzone University of Genoa

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