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Alessio Nencioni

Alessio Nencioni

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10185
World Ranking
12768
National Ranking
385

Overview

Alessio Nencioni is affiliated with the University of Genoa in Italy and has contributed extensively to research in medicine, particularly in the fields of biochemistry, genetics, and molecular biology. Their scholarly output encompasses 156 publications in medicine and 47 focused on biochemistry, genetics, and molecular biology. Key subfields include physiology, geriatrics and gerontology, molecular biology, oncology, and epidemiology.

The scientist's main research topics include frailty in older adults, sirtuins and resveratrol in medicine, nutrition and health in aging, PARP inhibition in cancer therapy, dietary effects on health, calcium signaling and nucleotide metabolism, and diet and metabolism studies.

Frequent co-authors of Alessio Nencioni feature several collaborators with whom they have published multiple works. These co-authors include Fiammetta Monacelli, Irene Caffa, Luca Tagliafico, Santina Bruzzone, and Pamela Becherini. The recurring partnership with these researchers indicates collaborative efforts across various scientific inquiries.

Alessio Nencioni has published in various high-impact and specialized venues. Most frequent publication venues are:

  • Cancers (6 publications)
  • Frontiers in Medicine (6 publications)
  • Nature (4 publications)
  • Nutrients (4 publications)
  • Journal of the American Medical Directors Association (4 publications)

Representative recent papers include:

  • "Fasting-mimicking diet and hormone therapy induce breast cancer regression," 2020, Nature
  • "Dendritic cells direct circadian anti-tumour immune responses," 2022, Nature
  • "Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers," 2020, Nature Communications
  • "Safety and Feasibility of Fasting-Mimicking Diet and Effects on Nutritional Status and Circulating Metabolic and Inflammatory Factors in Cancer Patients Undergoing Active Treatment," 2021, Cancers
  • "Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models," 2022, Cell Reports

The research outputs often explore intersections of diet, metabolism, and disease mechanisms, demonstrating an emphasis on nutrition's role in cancer therapy, neuroinflammation, and aging processes.

Best Publications

  • Fasting and cancer: molecular mechanisms and clinical application

    Alessio Nencioni;Irene Caffa;Salvatore Cortellino;Valter D. Longo

  • Dendritic Cell Immunogenicity Is Regulated by Peroxisome Proliferator-Activated Receptor γ

    Alessio Nencioni;Frank Grünebach;Anke Zobywlaski;Claudio Denzlinger

  • Proteasome inhibitors: antitumor effects and beyond.

    A Nencioni;F Grünebach;F Patrone;A Ballestrero

  • Fasting-mimicking diet and hormone therapy induce breast cancer regression

    Irene Caffa;Vanessa Spagnolo;Claudio Vernieri;Francesca Valdemarin

  • Vitamin C, Aging and Alzheimer's Disease.

    Fiammetta Monacelli;Erica Acquarone;Chiara Giannotti;Roberta Borghi

  • Transfection of dendritic cells with RNA induces CD4- and CD8-mediated T cell immunity against breast carcinomas and reveals the immunodominance of presented T cell epitopes.

    Martin R. Müller;Frank Grünebach;Alessio Nencioni;Peter Brossart

  • Catastrophic NAD + Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

    Santina Bruzzone;Floriana Fruscione;Sara Morando;Tiziana Ferrando

  • Pathophysiological role of neutrophils in acute myocardial infarction.

    Federico Carbone;Alessio Nencioni;François Mach;Nicolas Vuilleumier

  • Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity.

    Alessio Nencioni;Julia Beck;Daniela Werth;Frank Grünebach

  • The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.

    Inga Bauer;Alessia Grozio;Denise Lasigliè;Giovanna Basile

  • Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation.

    Alessio Nencioni;Karin Schwarzenberg;Karin Schwarzenberg;Katharina M. Brauer;Katharina M. Brauer;Susanne M. Schmidt;Susanne M. Schmidt

  • CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells

    Alessia Grozio;Giovanna Sociali;Laura Sturla;Irene Caffa

  • Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes.

    F Grünebach;M R Müller;A Nencioni;P Brossart

  • Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition

    Michele Cea;Antonia Cagnetta;Mariateresa Fulciniti;Yu Tzu Tai

  • Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis

    Alessio Nencioni;Fei Hua;Christopher P. Dillon;Rayka Yokoo

  • RNAI AS AN EXPERIMENTAL AND THERAPEUTIC TOOL TO STUDY AND REGULATE PHYSIOLOGICAL AND DISEASE PROCESSES

    Christopher P. Dillon;Peter Sandy;Alessio Nencioni;Stephan Kissler

  • Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer

    David Norman Brown;Irene Caffa;Gabriella Cirmena;Daniela Piras

  • The use of dendritic cells in cancer immunotherapy

    Alessio Nencioni;Frank Grünebach;Susanne M. Schmidt;Martin R. Müller

  • Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE.

    Santina Bruzzone;Floriana Fruscione;Sara Morando;Alessandro Poggi

  • mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition

    Michele Cea;Antonia Cagnetta;Mariateresa Fulciniti;Yu-Tzu Tai

Frequent Co-Authors

Santina Bruzzone
Santina Bruzzone University of Genoa
Fabrizio Montecucco
Fabrizio Montecucco University of Genoa
Peter Brossart
Peter Brossart University Hospital Bonn
Valter D. Longo
Valter D. Longo University of Southern California
François Mach
François Mach University of Geneva
Frank Grünebach
Frank Grünebach University of Tübingen
Alessandro Poggi
Alessandro Poggi University of Modena and Reggio Emilia
Franco Dallegri
Franco Dallegri University of Genoa
Pierre Vogel
Pierre Vogel École Polytechnique Fédérale de Lausanne
Kenneth C. Anderson
Kenneth C. Anderson Harvard University

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