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Biology and Biochemistry

D-Index
91
Citations
42117
World Ranking
2277
National Ranking
1220

Overview

Valter D. Longo is affiliated with the University of Southern California in the United States. Their research predominantly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields such as Physiology, Molecular Biology, Genetics, Endocrine and Autonomic Systems, and Endocrinology, Diabetes and Metabolism.

Their work covers a broad range of topics related to dietary effects on health and metabolism, including Dietary Effects on Health, Diet and Metabolism Studies, Circadian Rhythm and Melatonin, Nutrition, Genetics, and Disease, Genetics, Aging, and Longevity in Model Organisms, Diet, Metabolism, and Disease, as well as Nutritional Studies and Diet.

Longo's recent published papers include:

  • Fasting-mimicking diet and hormone therapy induce breast cancer regression, 2020, Nature
  • Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicenter randomized phase 2 DIRECT trial, 2020, Nature Communications
  • Nutrition, longevity and disease: From molecular mechanisms to interventions, 2022, Cell
  • Intermittent and periodic fasting, longevity and disease, 2021, Nature Aging
  • Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers, 2020, Nature Communications

The primary publication venues for Longo's research include Nature Communications, Cell Metabolism, Cancers, Cancer Research, and bioRxiv (Cold Spring Harbor Laboratory).

Among their frequent co-authors are Sebastian Brandhorst, Claudio Vernieri, Hanno Pijl, Salvatore Cortellino, and V. Spagnolo.

Best Publications

  • Extending Healthy Life Span-From Yeast to Humans

    Luigi Fontana;Linda Partridge;Valter D. Longo

  • Fasting: Molecular Mechanisms and Clinical Applications

    Valter D. Longo;Mark P. Mattson;Mark P. Mattson

  • Regulation of longevity and stress resistance by Sch9 in yeast.

    Paola Fabrizio;Fabiola Pozza;Scott D. Pletcher;Christi M. Gendron

  • Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

    Morgan E. Levine;Jorge A. Suarez;Sebastian Brandhorst;Priya Balasubramanian

  • A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

    Sebastian Brandhorst;In Young Choi;Min Wei;Chia Wei Cheng

  • The chronological life span of Saccharomyces cerevisiae.

    Paola Fabrizio;Valter D Longo

  • Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans.

    Jaime Guevara-Aguirre;Priya Balasubramanian;Marco Guevara-Aguirre;Min Wei

  • Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

    Changhan Lee;Lizzia Raffaghello;Sebastian Brandhorst;Sebastian Brandhorst;Fernando M. Safdie

  • Sirtuins in Aging and Age-Related Disease

    Valter D. Longo;Brian K. Kennedy

  • Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality.

    Mingyang Song;Teresa T. Fung;Frank B. Hu;Walter C. Willett;Walter C. Willett

  • Superoxide Dismutase Activity Is Essential for Stationary Phase Survival in Saccharomyces cerevisiae MITOCHONDRIAL PRODUCTION OF TOXIC OXYGEN SPECIES IN VIVO

    Valter D. Longo;Edith Butler Gralla;Joan Selverstone Valentine

  • Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy

    Lizzia Raffaghello;Changhan Lee;Fernando M. Safdie;Min Wei

  • Replicative and Chronological Aging in Saccharomyces cerevisiae

    Valter D. Longo;Gerald S. Shadel;Matt Kaeberlein;Matt Kaeberlein;Brian Kennedy;Brian Kennedy

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • Meal frequency and timing in health and disease

    Mark M.P. Mattson;Mark M.P. Mattson;David D.B. Allison;Luigi Fontana;Michelle Harvie

  • SIRT1 is essential for normal cognitive function and synaptic plasticity

    Shaday Michán;Ying Li;Maggie Meng Hsiu Chou;Edoardo Parrella

  • Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9.

    Min Wei;Paola Fabrizio;Jia Hu;Huanying Ge

  • A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.

    In Young Choi;Laura Piccio;Patra Childress;Bryan Bollman

  • Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression

    Chia-Wei Cheng;Gregor B. Adams;Laura Perin;Min Wei

  • Fasting and cancer treatment in humans: A case series report

    Fernando M. Safdie;Tanya Dorff;David Quinn;Luigi Fontana

Frequent Co-Authors

Alessio Nencioni
Alessio Nencioni University of Genoa
Luigi Fontana
Luigi Fontana University of Sydney
Pinchas Cohen
Pinchas Cohen University of Southern California
Rafael de Cabo
Rafael de Cabo National Institutes of Health
Brian K. Kennedy
Brian K. Kennedy National University of Singapore
Caleb E. Finch
Caleb E. Finch University of Southern California
David I. Quinn
David I. Quinn University of Southern California
Filippo de Braud
Filippo de Braud University of Milan
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Susan Groshen
Susan Groshen University of Southern California

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