World's Best Scientists 2026 revealed!
John J. Kopchick

John J. Kopchick

D-Index & Metrics

Medicine

D-Index
96
Citations
32411
World Ranking
9707
National Ranking
4995

Research.com Recognitions

  • 2012 - Fellow, National Academy of Inventors

Overview

John J. Kopchick is affiliated with Ohio University in the United States and has a prolific research presence primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work extensively covers subfields such as Endocrinology, Diabetes and Metabolism, Physiology, Molecular Biology, Cancer Research, and Endocrine and Autonomic Systems.

The main topics of their research include:

  • Growth Hormone and Insulin-like Growth Factors
  • Cancer, Hypoxia, and Metabolism
  • Diet and metabolism studies
  • Adipose Tissue and Metabolism
  • Regulation of Appetite and Obesity
  • Pituitary Gland Disorders and Treatments
  • Metabolism, Diabetes, and Cancer

Their recent publications demonstrate a focus on growth hormone function and related metabolic processes. Key papers include:

  • Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement, 2022, European Journal of Endocrinology
  • Effect of growth hormone on insulin signaling, 2020, Molecular and Cellular Endocrinology
  • Crosstalk between the growth hormone/insulin-like growth factor-1 axis and the gut microbiome: A new frontier for microbial endocrinology, 2020, Growth Hormone & IGF Research
  • Growth hormone receptor gene disruption in mature-adult mice improves male insulin sensitivity and extends female lifespan, 2021, Aging Cell
  • Tyrosine Hydroxylase Neurons Regulate Growth Hormone Secretion via Short-Loop Negative Feedback, 2020, Journal of Neuroscience

Frequently collaborating with other scientists, Kopchick has coauthored many publications with several colleagues, including:

  • Edward O. List
  • Reetobrata Basu
  • Darlene E. Berryman
  • Silvana Duran-Ortiz
  • J. A. Young

Their research has appeared in multiple journals, with a high number of publications in:

  • Journal of the Endocrine Society
  • Endocrinology
  • Pituitary
  • Journal of Neuroendocrinology
  • Cancer Research

John J. Kopchick was recognized as a Fellow of the National Academy of Inventors in 2012.

Best Publications

  • A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

    Yihua Zhou;Bixiong C. Xu;Hiralal G. Maheshwari;Li He

  • Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

    Karen T. Coschigano;David Clemmons;Linda L. Bellush;John J. Kopchick;John J. Kopchick

  • Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span.

    Karen T. Coschigano;Amy N. Holland;Markus E. Riders;Edward O. List

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • Growth hormone antagonists

    John J. Kopchick;Wen Y. Chen

  • Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression

    Chia-Wei Cheng;Gregor B. Adams;Laura Perin;Min Wei

  • The GH/IGF-1 axis in ageing and longevity

    Riia K. Junnila;Edward O. List;Darlene E. Berryman;John W. Murrey

  • Essential Role of Growth Hormone in Ischemia-Induced Retinal Neovascularization

    Lois E. H. Smith;Lois E. H. Smith;Lois E. H. Smith;John J. Kopchick;John J. Kopchick;John J. Kopchick;Wen Chen;Wen Chen;Wen Chen;Joanne Knapp;Joanne Knapp;Joanne Knapp

  • Growth Hormone Receptor Antagonists: Discovery, Development, and Use in Patients with Acromegaly

    J J Kopchick;Craig Parkinson;E C Stevens;Peter J Trainer

  • Growth hormone research society workshop summary: Consensus guidelines for recombinant human growth hormone therapy in Prader-Willi syndrome

    Cheri L. Deal;Michèle Tony;Charlotte Hoÿbye;David B. Allen

  • Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models

    Darlene E. Berryman;Jens Sandahl Christiansen;Gudmundur Johannsson;Michael O. Thorner

  • Growth hormone (GH), GH receptor, and signal transduction.

    John J. Kopchick;Jerald M. Andry

  • Comparing adiposity profiles in three mouse models with altered GH signaling

    Darlene E Berryman;Edward O List;Karen T Coschigano;Kevin Behar

  • Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1–deficient mice

    Shoshana Yakar;Jennifer Setser;Hong Zhao;Bethel Stannard

  • Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects.

    Marta I. Gallego;Nadine Binart;Gertraud W. Robinson;Ryugo Okagaki

  • Identification and expression of mammalian long-chain PUFA elongation enzymes.

    Amanda E. Leonard;Bruce Kelder;Emil G. Bobik;Lu-Te Chuang

  • A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update.

    Andrea Giustina;Ariel Barkan;Albert Beckers;Nienke Biermasz

  • Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism

    Yong Fan;Ram K. Menon;Pinchas Cohen;David Hwang

  • Bone homeostasis in growth hormone receptor–null mice is restored by IGF-I but independent of Stat5

    Natalie A. Sims;Philippe Clément-Lacroix;Francesca Da Ponte;Yasmina Bouali

  • Interventions to slow aging in humans: are we ready? [forthcoming]

    L Fontana;A Antebi;A Bartke;N Barzilai

Frequent Co-Authors

Andrzej Bartke
Andrzej Bartke Southern Illinois University School of Medicine
Jens Otto Lunde Jørgensen
Jens Otto Lunde Jørgensen Aarhus University Hospital
Richard D. Cummings
Richard D. Cummings Harvard Medical School
Kelley W. Moremen
Kelley W. Moremen University of Georgia
David F. Smith
David F. Smith Emory University
Jose Donato
Jose Donato Universidade de São Paulo
Paul A. Kelly
Paul A. Kelly Queen Mary University of London
Michael O. Thorner
Michael O. Thorner University of Virginia
Stuart J. Frank
Stuart J. Frank University of Alabama at Birmingham
Richard A. Miller
Richard A. Miller University of Michigan–Ann Arbor

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Many students interested in medicine may also consider online degrees and alternative career pathways within the healthcare field. Flexible learning and growing demand have led to numerous accredited programs that can boost your qualifications and job prospects.

For those drawn toward mental health, online pmhnp programs are an excellent way to become a Psychiatric-Mental Health Nurse Practitioner. These options often allow for faster completion and remote coursework, making them ideal for working nurses.

If administration interests you more than direct patient care, consider a healthcare administration degree online. These degrees teach essential skills in leadership, policy, and management, opening doors to supervisory roles in clinics, hospitals, and public health organizations.

Affordability matters, too. Explore the cheapest mha programs to earn your Master of Healthcare Administration without high costs, or check the cheapest dnp programs if you plan to pursue advanced nursing practice.

Whether your interests lie in clinical care or leadership, these flexible online options support diverse goals within the healthcare field.

Best Scientists Citing John J. Kopchick

Trending Scientists

Recently Published Articles