D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 127 Citations 55,117 602 World Ranking 1617 National Ranking 955

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Cancer

His primary areas of study are Internal medicine, Endocrinology, Insulin-like growth factor, Insulin and Insulin receptor. His research combines Type 2 diabetes and Internal medicine. His biological study spans a wide range of topics, including Gene expression and Phosphorylation, Cell biology.

Derek LeRoith combines subjects such as Autocrine signalling, Cell growth, Growth hormone, Molecular biology and Messenger RNA with his study of Insulin-like growth factor. His study in Insulin is interdisciplinary in nature, drawing from both Protein kinase B, AMPK and Type 2 Diabetes Mellitus. His studies in Insulin receptor integrate themes in fields like Insulin-like growth factor 1 receptor and Signal transduction, Biochemistry.

His most cited work include:

  • Molecular and cellular aspects of the insulin-like growth factor I receptor (1265 citations)
  • Normal growth and development in the absence of hepatic insulin-like growth factor I (1231 citations)
  • The insulin-like growth factor system and cancer. (961 citations)

What are the main themes of his work throughout his whole career to date?

Derek LeRoith mainly investigates Internal medicine, Endocrinology, Insulin, Receptor and Diabetes mellitus. As a member of one scientific family, Derek LeRoith mostly works in the field of Internal medicine, focusing on Type 2 diabetes and, on occasion, Cognition. His Endocrinology research includes themes of Gene expression, Signal transduction and Growth factor.

He focuses mostly in the field of Receptor, narrowing it down to matters related to Cancer research and, in some cases, Cancer cell. The study incorporates disciplines such as Obesity, Disease, Bioinformatics and Intensive care medicine in addition to Diabetes mellitus. Derek LeRoith has researched Insulin receptor in several fields, including Insulin-like growth factor 1 receptor and Phosphorylation, Cell biology.

He most often published in these fields:

  • Internal medicine (57.07%)
  • Endocrinology (52.18%)
  • Insulin (26.18%)

What were the highlights of his more recent work (between 2013-2021)?

  • Internal medicine (57.07%)
  • Type 2 diabetes (14.83%)
  • Endocrinology (52.18%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Internal medicine, Type 2 diabetes, Endocrinology, Diabetes mellitus and Insulin. His work in Internal medicine tackles topics such as Oncology which are related to areas like Epidemiology. His work on Adipose tissue as part of general Endocrinology study is frequently linked to Caspase 3, bridging the gap between disciplines.

His work deals with themes such as Surgery, Disease, Haptoglobin and Intensive care medicine, which intersect with Diabetes mellitus. Derek LeRoith studies Insulin, focusing on Insulin receptor in particular. His research integrates issues of Insulin-like growth factor 1 receptor, Cancer research and Receptor in his study of Insulin receptor.

Between 2013 and 2021, his most popular works were:

  • American association of clinical endocrinologists and american college of endocrinology - clinical practice guidelines for developing a diabetes mellitus comprehensive care plan - 2015. (442 citations)
  • Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality. (304 citations)
  • AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY POSITION STATEMENT ON THE ASSOCIATION OF SGLT-2 INHIBITORS AND DIABETIC KETOACIDOSIS. (165 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Type 2 diabetes, Diabetes mellitus and Hyperinsulinemia. His Internal medicine research is multidisciplinary, relying on both Oncology and Bioinformatics. His Endocrinology study combines topics from a wide range of disciplines, such as Mammary tumor and Bone marrow.

His Type 2 diabetes study incorporates themes from Type 1 diabetes, Cognition, Cognitive decline and Glycemic. His Diabetes mellitus research is multidisciplinary, incorporating perspectives in Adverse effect, Surgery and Intensive care medicine. His Hyperinsulinemia research incorporates elements of Cancer, Dyslipidemia and PI3K/AKT/mTOR pathway.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Molecular and cellular aspects of the insulin-like growth factor I receptor

Derek LeRoith;Haim Werner;Dana Beitner-Johnson;Charles T. Roberts.
Endocrine Reviews (1995)

1793 Citations

Normal growth and development in the absence of hepatic insulin-like growth factor I

Shoshana Yakar;Jun L.I. Liu;Bethel Stannard;Andrew Butler.
Proceedings of the National Academy of Sciences of the United States of America (1999)

1654 Citations

The insulin-like growth factor system and cancer.

Derek LeRoith;Charles T. Roberts.
Cancer Letters (2003)

1394 Citations

The role of the IGF system in cancer growth and metastasis: overview and recent insights.

Amir Abbas Samani;Shoshana Yakar;Derek LeRoith;Pnina Brodt.
Endocrine Reviews (2007)

1266 Citations

Circulating levels of IGF-1 directly regulate bone growth and density

Shoshana Yakar;Clifford J. Rosen;Wesley G. Beamer;Cheryl L. Ackert-Bicknell.
Journal of Clinical Investigation (2002)

1094 Citations

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

Klara Sjögren;Jun-Li Liu;Kristina Blad;Stanko Skrtic.
Proceedings of the National Academy of Sciences of the United States of America (1999)

1068 Citations

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

Marcelina Párrizas;Alan R. Saltiel;Derek LeRoith.
Journal of Biological Chemistry (1997)

798 Citations

Developmental and Tissue-Specific Sulfonylurea Receptor Gene Expression

Catalina Hernández-Sánchez;Teresa L. Wood;Derek LeRoith.
Endocrinology (1997)

784 Citations

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation

Keren Paz;Rina Hemi;Derek LeRoith;Avraham Karasik.
Journal of Biological Chemistry (1997)

772 Citations

Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity.

Ann Hellstrom;Carole Perruzzi;Meihua Ju;Eva Engström.
Proceedings of the National Academy of Sciences of the United States of America (2001)

713 Citations

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