World's Best Scientists 2026 revealed!
Michael Pollak

Michael Pollak

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Medicine
Canada
2023

D-Index & Metrics

Medicine

D-Index
139
Citations
81552
World Ranking
1741
National Ranking
63

Research.com Recognitions

  • 2023 - Research.com Medicine in Canada Leader Award
  • 2019 - Fellow of the Royal Society of Canada Academy of Science

Overview

Michael Pollak is affiliated with McGill University in Canada and has an extensive research portfolio focusing on medicine, biochemistry, genetics, and molecular biology. Their work spans several subfields including molecular biology, oncology, cancer research, endocrinology, diabetes and metabolism, as well as genetics. The primary topics of interest in their research include metabolism, diabetes, and cancer; cancer risks and factors; growth hormone and insulin-like growth factors; pancreatic and hepatic oncology research; genetic factors in colorectal cancer; cancer, hypoxia, and metabolism; and cancer genomics and diagnostics.

The scientist has published recent papers covering a range of biomedical topics. Notable publications include:

  • "A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity," 2021, Nature Medicine
  • "Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides," 2023, Science
  • "Clinically Relevant Circulating Protein Biomarkers for Type 1 Diabetes: Evidence From a Two-Sample Mendelian Randomization Study," 2021, Diabetes Care
  • "The role of GSK3 in metabolic pathway perturbations in cancer," 2021, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • "STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer," 2021, Nature Communications

Their frequent co-authors demonstrate ongoing collaborations with researchers in related fields. These co-authors include:

  • Neil M. Iyengar
  • Elizabeth A. Platz
  • Lewis C. Cantley
  • Urvi A. Shah
  • Andriy Derkach

Michael Pollak's work is often published in venues that focus on cancer and biomedical research. Some of the primary publication venues are:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Prevention Research
  • Cancer Epidemiology Biomarkers & Prevention
  • JNCI Cancer Spectrum

Among distinctions, Michael Pollak was named a Fellow of the Royal Society of Canada in 2019 by the Academy of Science. Their body of work contributes across multiple disciplines related to medicine and molecular biology with a focus on the mechanisms underlying cancer and metabolic diseases.

Best Publications

  • Diabetes and Cancer: A consensus report

    Edward L. Giovannucci;David M. Harlan;Michael C. Archer;Richard M. Bergenstal

  • Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study

    J.M. Chan;M.J. Stampfer;E. Giovannucci;P.H. Gann

  • Insulin and insulin-like growth factor signalling in neoplasia

    Michael Pollak

  • Circulating concentrations of insulin-like growth factor I and risk of breast cancer

    Susan E Hankinson;Walter C Willett;Walter C Willett;Graham A Colditz;Graham A Colditz;David J Hunter;David J Hunter

  • Insulin-like growth factors and neoplasia.

    Michael N. Pollak;Eva S. Schernhammer;Susan E. Hankinson

  • Metformin improves healthspan and lifespan in mice

    Alejandro Martin-Montalvo;Evi M. Mercken;Sarah J. Mitchell;Sarah J. Mitchell;Sarah J. Mitchell;Hector H. Palacios

  • Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF-Binding Protein-3

    Jing Ma;Michael N. Pollak;Edward Giovannucci;June M. Chan

  • Metformin: From Mechanisms of Action to Therapies

    Marc Foretz;Bruno Guigas;Luc Bertrand;Michael Pollak

  • Anastrozole Is Superior to Tamoxifen as First-Line Therapy for Advanced Breast Cancer in Postmenopausal Women: Results of a North American Multicenter Randomized Trial

    J. M. Nabholtz;A. Buzdar;M. Pollak;W. Harwin

  • Metformin is an AMP Kinase-Dependent Growth Inhibitor for Breast Cancer Cells

    Mahvash Zakikhani;Ryan Dowling;I George Fantus;Nahum Sonenberg

  • The insulin and insulin-like growth factor receptor family in neoplasia: an update

    Michael Pollak

  • Metformin Inhibits Mammalian Target of Rapamycin–Dependent Translation Initiation in Breast Cancer Cells

    Ryan J.O. Dowling;Mahvash Zakikhani;I. George Fantus;Michael Pollak

  • Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)

    Yuhong Lu;Xiaolin Zi;Yunhua Zhao;Desmond Mascarenhas

  • mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

    Masahiro Morita;Simon Pierre Gravel;Valérie Chénard;Kristina Sikström

  • Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.

    Hannah R. Bridges;Andrew J. Y. Jones;Michael N. Pollak;Judy Hirst

  • Lifestyle Correlates of Plasma Insulin-like Growth Factor I and Insulin-like Growth Factor Binding Protein 3 Concentrations

    Michelle D. Holmes;Michael N. Pollak;Susan E. Hankinson

  • Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy

    Omer Kucuk;Fazlul H. Sarkar;Wael Sakr;Zora Djuric

  • A percolation treatment of dc hopping conduction

    M. Pollak

  • Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

    Jared R Mayers;Chen Wu;Chen Wu;Clary B Clish;Peter Kraft

  • eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

    Luc Furic;Liwei Rong;Ola Larsson;Ismaël Hervé Koumakpayi

Frequent Co-Authors

Susan E. Hankinson
Susan E. Hankinson University of Massachusetts Amherst
Meir J. Stampfer
Meir J. Stampfer Harvard University
Walter C. Willett
Walter C. Willett Harvard University
Kathleen I. Pritchard
Kathleen I. Pritchard University of Toronto
Martin E. Gleave
Martin E. Gleave University of British Columbia
Demetrius Albanes
Demetrius Albanes National Institutes of Health
Graham A. Colditz
Graham A. Colditz Washington University in St. Louis
Robert C. Kaplan
Robert C. Kaplan Albert Einstein College of Medicine
Frank B. Hu
Frank B. Hu Harvard University

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