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Immunology

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Overview

Katie J. Ewer is affiliated with the University of Oxford in the United Kingdom. Their research activity is concentrated primarily within the field of Medicine, with a strong specialization in Infectious Diseases, Public Health, Environmental and Occupational Health, Immunology, Epidemiology, and Molecular Biology.

The main topics of Katie J. Ewer's research include SARS-CoV-2 and COVID-19 research, malaria research and control, vaccines and immunoinformatics approaches, COVID-19 clinical research studies, mosquito-borne diseases and control, viral infections and outbreaks research, and immunotherapy and immune responses.

Their recent published papers feature significant contributions to understanding vaccine safety, efficacy, and immunogenicity, mostly related to the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2. Notable papers include:

  • Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK, 2020, The Lancet
  • Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial, 2020, The Lancet
  • Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection, 2021, Nature Medicine
  • Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials, 2021, The Lancet
  • Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial, 2021, The Lancet

Frequent co-authors collaborating with Katie J. Ewer include Adrian V. S. Hill, Duncan Bellamy, Sarah C. Gilbert, Pedro M. Folegatti, and Daniel Jenkin.

Their work is published regularly in the following venues:

  • SSRN Electronic Journal
  • The Lancet
  • Nature Medicine
  • Frontiers in Immunology
  • The Lancet Infectious Diseases

Best Publications

  • Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.

    M Voysey;Clemens Sac.;S A Madhi;L Y Weckx

  • Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

    P M Folegatti;K J Ewer;P K Aley;B Angus

  • Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

    M Voysey;S A Costa Clemens;S A Madhi;L Y Weckx

  • Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.

    M N Ramasamy;A M Minassian;K J Ewer;A L Flaxman

  • Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak

    Katie Ewer;Jonathan Deeks;Lydia Alvarez;Gerry Bryant

  • Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

    Pedro M Folegatti;Katie J Ewer;Parvinder K Aley;Brian Angus

  • Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial.

    Katherine R W Emary;Tanya Golubchik;Parvinder K Aley;Cristina V Ariani

  • T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial.

    K J Ewer;Barrett;S Belij-Rammerstorfer;H Sharpe

  • Diagnosis of tuberculosis in South African children with a T-cell-based assay: a prospective cohort study.

    Susan Liebeschuetz;Sheila Bamber;Katie Ewer;Jonathan Deeks

  • Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells.

    Ann L. N. Chapman;Mwansa Munkanta;Katalin A. Wilkinson;Ansar A. Pathan

  • Enumeration of T Cells Specific for RD1-Encoded Antigens Suggests a High Prevalence of Latent Mycobacterium tuberculosis Infection in Healthy Urban Indians

    Ajit Lalvani;Punam Nagvenkar;Zarir Udwadia;Ansar A. Pathan

  • Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial

    Mehreen S Datoo;Magloire H Natama;Athanase Somé;Ousmane Traoré

  • Potent CD8+ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA−NP+M1

    Tamara K. Berthoud;Matthew Hamill;Patrick J. Lillie;Lenias Hwenda

  • Safety and Immunogenicity of Novel Adenovirus Type 26– and Modified Vaccinia Ankara–Vectored Ebola Vaccines: A Randomized Clinical Trial

    Iain D. Milligan;Malick M. Gibani;Richard Sewell;Elizabeth A. Clutterbuck

  • Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study

    Ahmet Soysal;Kerry A Millington;Mustafa Bakir;Davinder Dosanjh

  • Protective CD8 + T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

    Katie J Ewer;Geraldine A O'Hara;Christopher J A Duncan;Katharine A Collins

  • Vaccine Vectors Derived from a Large Collection of Simian Adenoviruses Induce Potent Cellular Immunity Across Multiple Species

    Stefano Colloca;Eleanor Barnes;Antonella Folgori;Virginia Ammendola

  • A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

    Katie Ewer;Tommy Rampling;Navin Venkatraman;Georgina Bowyer

  • Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses.

    Barrett;S Belij-Rammerstorfer;C Dold;K J Ewer

  • Dynamic antigen-specific T-cell responses after point-source exposure to Mycobacterium tuberculosis.

    Katie Ewer;Kerry A. Millington;Jonathan J. Deeks;Lydia Alvarez

  • Single Dose Administration, And The Influence Of The Timing Of The Booster Dose On Immunogenicity and Efficacy Of ChAdOx1 nCoV-19 (AZD1222) Vaccine (preprint)

    Voysey, Merryn, Costa Clemens, Sue Ann, Madhi, Shabir A.;Weckx, Lily Yin, Folegatti, Pedro M.;Parvinder K. Aley;Angus, Brian John, Baillie, Vicky, Barnabas, Shaun L.

Frequent Co-Authors

Adrian V. S. Hill
Adrian V. S. Hill University of Oxford
Sarah C. Gilbert
Sarah C. Gilbert University of Oxford
Ajit Lalvani
Ajit Lalvani Imperial College London
Teresa Lambe
Teresa Lambe University of Oxford
Alfredo Nicosia
Alfredo Nicosia University of Naples Federico II
Ian D. Poulton
Ian D. Poulton University of Oxford
Saul N. Faust
Saul N. Faust University Hospital Southampton NHS Foundation Trust
Andrew J. Pollard
Andrew J. Pollard University of Oxford
Riccardo Cortese
Riccardo Cortese Schering-Plough
Simon J. Draper
Simon J. Draper University of Oxford

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